Kooperationseinheit Translationale Studien und Biomarker
Prof. Dr. Inga Zerr
Leiterin Kooperations-Einheit
Robert-Koch-Str. 40
37075 Göttingen

inga.zerr@dzne.de
 +49 551 39-66636

Publikationen

Die vollständige Publikatinslsite findet man hier.

Diana G Ferreira, Mariana Temido-Ferreira, Hugo Vicente Miranda, Vânia L Batalha, Joana E Coelho, Éva M Szegö, Inês Marques-Morgado, Sandra H Vaz, Jeong Seop Rhee, Matthias Schmitz, Inga Zerr, Luísa V Lopes, Tiago F. Outeiro. α-synuclein interacts with PrP C to induce cognitive impairment through mGluR5 and NMDAR2B. Nature Neuroscience. 2016 Dec 31; 20:1569-1579. doi: 10.1038/nn.4648
Paula Garcia-Esparcia, Irene López-González, Oriol Grau-Rivera, María Francisca García-Garrido, Anusha Konetti, Franc Llorens, Saima Zafar, Margarita Carmona, José Antonio del Rio, Inga Zerr, Ellen Gelpi, Isidro Ferrer. Dementia with lewy bodies: Molecular pathology in the frontal cortex in typical and rapidly progressive forms. Frontiers in Neurology. 2017 Mar 12; 8 doi: 10.3389/fneur.2017.00089
Franc Llorens, Niels Kruse, Matthias Schmitz, Nadine Gotzmann, Ewa Golanska, Katrin Thüne, Orgeta Zejneli, Eirini Kanata, Tobias Knipper, Maria Cramm, Peter Lange, Saima Zafar, Beata Sikorska, Pawel P. Liberski, Eva Mitrova, Daniela Varges, Christian Schmidt, Theodoros Sklaviadis, Brit Mollenhauer, Inga Zerr. Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases. Alzheimer's and Dementia. 2017 May 31; 13:710-719. doi: 10.1016/j.jalz.2016.09.013
Franc Llorens, Matthias Schmitz, André Karch, Maria Cramm, Peter Lange, Kerim Gherib, Daniela Varges, Christian Schmidt, Inga Zerr, Katharina Stoeck. Comparative analysis of cerebrospinal fluid biomarkers in the differential diagnosis of neurodegenerative dementia. Alzheimer's and Dementia. 2016 Apr 30; 12:577-589. doi: 10.1016/j.jalz.2015.10.009
Schmitz M, Cramm M, Llorens F, Müller-Cramm D, Collins S, Atarashi R, Satoh K, Orrù CD, Groveman BR, Zafar S, Schulz-Schaeffer WJ, Caughey B, Zerr I. The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases. Nat Protoc. 2016 Jan 01; 11:2233-42.
Franc Llorens, Matthias Schmitz, Daniela Varges, Niels Kruse, Nadine Gotzmann, Karin Gmitterová, Brit Mollenhauer, Inga Zerr. Cerebrospinal α-synuclein in α-synuclein aggregation disorders: tau/α-synuclein ratio as potential biomarker for dementia with Lewy bodies. Journal of Neurology. 2016 Oct 31; 263:2271-2277. doi: 10.1007/s00415-016-8259-0
Matthias Schmitz, Maria Cramm, Franc Llorens, Niccolò Candelise, Dominik Müller-Cramm, Daniela Varges, Walter J. Schulz-Schaeffer, Saima Zafar, Inga Zerr. Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie. Scientific Reports. 2016 Jul 06; 6 doi: 10.1038/srep28711
Zafar S, Schmitz M, Karch A, Mitrova E, Kuhn F, Schroeder B, Raeber A, Varges D, Kim YS, Satoh K, Collins S, Zerr I. Creutzfeldt-Jakob disease subtype-specific regional and temporal regulation of ADP ribosylation factor-1-dependent Rho/MLC pathway at pre-clinical stage. J Mol Neurosci. 2015 Jan 01; 53:329-48.
Maria Cramm, Matthias Schmitz, André Karch, Saima Zafar, Daniela Varges, Eva Mitrova, Bjoern Schroeder, Alex Raeber, Franziska Kuhn, Inga Zerr. Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases. Molecular Neurobiology. 2013 Dec 31; 51:396-405. doi: 10.1007/s12035-014-8709-6
Zafar S, Asif AR, Ramljak S, Tahir W, Schmitz M, Zerr I. Anchorless 23-230 PrPC interactomics for elucidation of PrPC protective role. Mol Neurobiol. 2014 Jan 01; 49:1385-99.
Zafar S, Younas N, Sheikh N, Tahir W, Shafiq M, Schmitz M, Ferre I, Andréoletti O, Zerr I. Cytoskeleton associated risk modifiers involved in early and rapid progression of sporadic Creutzfeldt-Jakob disease. Mol Neurobiol. 2017 Jul 01; doi: 10.1007/s12035-017-0589-0
Zafar S, Shafiq M, Younas N, Schmitz M, Ferre I, Zerr I. Prion protein interactome: identifying novel targets in slowly and rapidly progressive forms of Alzheimer’s disease. J Alzheimers Dis. 2017 Jan 01; 59:265-275. doi: 10.3233/JAD-170237
Zafar S, Behrens C, Dihazi H, Schmitz M, Zerr I, Schulz-Schaeffer WJ, Ramljak S, Asif AR. Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells. Nature- Cell Death Dis. 2017 Jan 19; 8:e2557. doi: 10.1038/cddis.2016.384

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