Cooperation Unit Translational studies and biomarker
Prof. Dr. Inga Zerr
Leader Cooperation Unit
Robert-Koch-Str. 40
37075 Göttingen

inga.zerr@dzne.de
 +49 551 39-66636

Publications

The complete list of publications is found here.

Candelise N, Schmitz M, Llorens F, Villar-Piqué A, Cramm M, Thom T, da Silva Correia SM, da Cunha JEG, Möbius W, Outeiro TF, Álvarez VG, Banchelli M, D'Andrea C, de Angelis M, Zafar S, Rabano A, Matteini P, Zerr I. Seeding variability of different alpha synuclein strains in synucleinopathies. Ann Neurol. 2019 May 01; 85:691-703. doi: 10.1002/ana.25446
Schmitz M, Villar-Piqué A, Llorens F, Gmitterová K, Hermann P, Varges D, Zafar S, Lingor P, Vanderstichele H, Demeyer L, Stoops E, Trojanowski JQ, Lee VM, Zerr I. Cerebrospinal Fluid Total and Phosphorylated α-Synuclein in Patients with Creutzfeldt-Jakob Disease and Synucleinopathy. Mol Neurobiol. 2019 Nov 19; 56:3476-3483. doi: 10.1007/s12035-018-1313-4
Vallabh SM, Nobuhara CK, Llorens F, Zerr I, Parchi P, Capellari S, Kuhn E, Klickstein J, Safar JG, Nery FC, Swoboda KJ, Geschwind MD, Zetterberg H, Arnold SE, Minikel EV, Schreiber SL. Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development. Proc Natl Acad Sci U S A. 2019 Apr 16; 116:7793-7798. doi: 10.1073/pnas.1901947116
Inga Zerr, Matthias Schmitz, André Karch, Anna Villar-Piqué, Eirini Kanata, Ewa Golanska, Daniela Díaz-Lucena, Aikaterini Karsanidou, Peter Hermann, Tobias Knipper, Stefan Goebel, Daniela Varges, Theodoros Sklaviadis, Beata Sikorska, Pawel P. Liberski, Isabel Santana, Isidro Ferrer, Henrik Zetterberg, Kaj Blennow, Olga Calero, Miguel Calero, Anna Ladogana, Raquel Sánchez-Valle, Inês Baldeiras, Franc Llorens. Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases. Alzheimer's and Dementia. 2018 May 31; 14:751-763. doi: 10.1016/j.jalz.2017.12.008
Hermann P, Laux M, Glatzel M, Matschke J, Knipper T, Goebel S, Treig J, Schulz-Schaeffer W, Cramm M, Schmitz M, Zerr I. Validation and utilization of amended diagnostic criteria in Creutzfeldt-Jakob disease surveillance. Neurology. 2018 Jul 24; 91:e331-e338. doi: 10.1212/WNL.0000000000005860
Tahir W, Zafar S, Llorens F, Arora AS, Thüne K, Schmitz M, Gotzmann N, Kruse N, Mollenhauer B, Torres JM, Andréoletti O, Ferrer I, Zerr I. Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt-Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress. Mol Neurobiol. 2018 Jan 01; 55:517-537. doi: 10.1007/s12035-016-0294-4
Ferreira DG, Temido-Ferreira M, Vicente Miranda H, Batalha VL, Coelho JE, Szegö EM, Marques-Morgado I, Vaz SH, Rhee JS, Schmitz M, Zerr I, Lopes LV, Outeiro TF. α-Synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B. Nat Neurosci. 2017 Nov 01; 20:1569-1579. doi: 10.1038/nn.4648
Zafar S, Younas N, Correia S, Shafiq M, Tahir W, Schmitz M, Ferrer I, Andréoletti O, Zerr I. Strain-Specific Altered Regulatory Response of Rab7a and Tau in Creutzfeldt-Jakob Disease and Alzheimer's Disease. Mol Neurobiol. 2017 Jan 02; 54:697-709. doi: 10.1007/s12035-016-9694-8
Zafar S, Shafiq M, Younas N, Schmitz M, Ferrer I, Zerr I. Prion Protein Interactome: Identifying Novel Targets in Slowly and Rapidly Progressive Forms of Alzheimer's Disease. J Alzheimers Dis. ; 59:265-275. doi: 10.3233/JAD-170237
Schmitz M, Cramm M, Llorens F, Müller-Cramm D, Collins S, Atarashi R, Satoh K, Orrù CD, Groveman BR, Zafar S, Schulz-Schaeffer WJ, Caughey B, Zerr I. The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases. Nat Protoc. 2016 Nov 01; 11:2233-2242. doi: 10.1038/nprot.2016.120
Matthias Schmitz, Maria Cramm, Franc Llorens, Niccolò Candelise, Dominik Müller-Cramm, Daniela Varges, Walter J. Schulz-Schaeffer, Saima Zafar, Inga Zerr. Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie. Scientific Reports. 2016 Jul 06; 6 doi: 10.1038/srep28711
Maria Cramm, Matthias Schmitz, André Karch, Saima Zafar, Daniela Varges, Eva Mitrova, Bjoern Schroeder, Alex Raeber, Franziska Kuhn, Inga Zerr. Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases. Molecular Neurobiology. 2013 Dec 31; 51:396-405. doi: 10.1007/s12035-014-8709-6

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