Clinical Research at DZNE
The path to new therapies
Clinical research forms the hinge between the laboratories and the bedside: Newly developed active substances are tested on patients, innovative treatment strategies are developed and diagnostic procedures are tried out. At the DZNE, clinical research focuses on a broad spectrum of diseases - from dementias such as Alzheimer's to movement disorders such as Parkinson's and ALS.
To this end, the scientists at the DZNE cooperate very closely with numerous university hospitals throughout Germany; they also participate in international projects. Through this networking, they bundle know-how from many areas.
Improving diagnostic procedures plays an important role in clinical research: Because the brain in neurodegenerative diseases has often already changed over many years before the first symptoms of the disease appear, early diagnosis is crucial for the chances of treatment. Researchers are therefore looking for ways to detect the hidden beginnings of such diseases in time. Observational studies, on the other hand, are used to investigate the course of diseases and their signs. And in treatment studies, the scientists are investigating new drugs, among other things.
Clinical research is based at the DZNE sites in Berlin, Bonn, Dresden, Göttingen, Magdeburg, Munich, Rostock/Greifswald, Tübingen and Ulm.
Clinical Research Platform - CRP
The multi-site studies of the DZNE are supported and coordinated by the
Clinical Research Platform ...
Databases of Clinical Research
Here you'll find the Databases of DZNE's Clinical Research.
Further information regarding the access requirements can be found here.
Support: In case of questions or issues, please contact the data management of the clinical research platform: data-management-kf(at)dzne.de.
Requirements: The request form for database access, the declaration of commitment and the regulations for use of Clinical Research databases, data and biomaterial samples of the DZNE can be downloaded here:
- Request for access to the databases of the clinical research (German only)
- Declaration of commitment by users of the clinical databases (German only)
- Regulations for use of Clinical Research databases, data and biomaterials of the DZNE
The request form can be sent either by mail or e-mail, the declaration of commitment by mail only to the rights management of the clinical research:
Deutsches Zentrum für Neurodegenerativer Erkrankungen e.V.
Klinische Forschungsplattform - Rechtemanagement
Venusberg-Campus 1/99
D-53127 Bonn
zentrales-rechtemanagement-DB(at)dzne.de
Important note: In case PDF forms are not displayed properly using Firefox, e.g. without editable form fields, follow these instructions and choose "Open with Adobe Acrobat Reader": Disable the built in pdf-viewer and use another viewer
Clinical Data Search Tool - CDST
The Clinical Data Search Tool - CDST offers the opportunity to retrieve information on available data/materials from clinical research studies.
The CDST provides purely qualitative information (no number of available datasets) such as
- Forms (= examinations such as tests, scales, imaging, biomaterial, etc.) and
- Parameters (= Variables/Items),
for which results are available in the clinical research databases for a particular study.
For each study
- individual forms completely (> Formular drucken) as well as
- parameters from several forms (> ausgewählte Items: … > Auswahl drucken)
can be saved as a PDF file and, if necessary, attached to the Request for Data and Biomaterial.
Please note that this does not replace the request, it can serve only as a supplement.
Request for Data and Biomaterial / Biobank Report
The data/biomaterial request form and the regulations for use of Clinical Research databases, data and biomaterial can be downloaded here:
- Data/Biomaterial Request Form
- Regulations for use of Clinical Research databases, data and biomaterials of the DZNE
Please, send the request form to klinische-studien(at)dzne.de.
Please also use the Clinical Data Search Tool - CDST to specify your request or to clarify in advance which parameters/biomaterial samples/MRT sequences/QA information/analysis results are available for the individual studies.
- Report of DZNE's Clinical Research Biobank (German only)
Important note: In case PDF forms are not displayed properly using Firefox, e.g. without editable form fields, follow these instructions and choose "Open with Adobe Acrobat Reader": Disable the built in pdf-viewer and use another viewer
Central Contact Management / Content Responsibility
Central Contact Management
The central contact management is the point of contact for study participants (probands).
zentrale-kontaktstelle-kf(at)dzne.de
Content responsibility
The Clinical Research Platform is responsible for the contents of DZNE's Clinical Research website.
DECLARE - DZNE Clinical Research E-Learning Platform
Here you'll find DECLARE, the DZNE Clinical Research E-Learning Platform.
Requirements: The request form for access to the DZNE Clinical Research E-Learning Platform as well as the Terms of Use can be downloaded here:
Please send the request via e-mail to the Clinical Research Platform of the DZNE.
Important note: In case PDF forms are not displayed properly using Firefox, e.g. without editable form fields, follow these instructions and choose "Open with Adobe Acrobat Reader": Disable the built in pdf-viewer and use another viewer