Prionen Zellbiologie
Prof. Dr. Ina Maja Vorberg
Gruppenleiterin
Sigmund-Freud-Str. 27
53127 Bonn

ina.vorberg@dzne.de
 +49 228 43302-560

Publikationen

Die vollständige Publikationsliste findet man hier.

Fehlinger A, Wolf H, Hossinger A, Duernberger Y, Pleschka C, Riemschoss K, Liu S, Bester R, Paulsen L, Priola SA, Groschup MH, Schatzl HM, Vorberg IM. Prion strains depend on different endocytic routes for productive infection. Sci Rep. 2017 Jan 01; 7:6923. doi: 10.1038/s41598-017-07260-2
Shu Liu, André Hossinger, Julia P. Hofmann, Philip Denner, Ina M. Vorberg. Horizontal transmission of cytosolic sup35 prions by extracellular vesicles. mBio. 2016 Jun 30; 7 doi: 10.1128/mBio.00915-16
Wolf H, Hossinger A, Fehlinger A, Buttner S, Sim V, McKenzie D, Vorberg IM. Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie. Front Neurosci. 2015 Jan 01; 9:410. doi: 10.3389/fnins.2015.00410
Wolf H, Grassmann A, Bester R, Hossinger A, Mohl C, Paulsen L, Groschup MH, Schatzl H, Vorberg I. Modulation of Glycosaminoglycans Affects PrPSc Metabolism but Does Not Block PrPSc Uptake. J Virol. 2015 Jan 01; 89:9853-64. doi: 10.1128/JVI.01276-15
Julia P. Hofmann, Philip Denner, Carmen Nussbaum-Krammer, Peer-Hendrik Kuhn, Michael H. Suhre, Thomas Scheibel, Stefan F. Lichtenthaler, Hermann M. Schätzl, Daniele Bano, Ina M. Vorberg. Cell-to-cell propagation of infectious cytosolic protein aggregates. Proceedings of the National Academy of Sciences of the United States of America. 2013 Apr 08; 110:5951-5956. doi: 10.1073/pnas.1217321110
Iva Hafner-Bratkovič, Romina Bester, Primož Pristovšek, Lars Gaedtke, Peter Veranič, Jernej Gašperšič, Mateja Manček-Keber, Matevž Avbelj, Magdalini Polymenidou, Christian Julius, Adriano Aguzzi, Ina Vorberg, Roman Jerala. Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion. Journal of Biological Chemistry. 2011 Apr 07; 286:12149-12156. doi: 10.1074/jbc.M110.213926
Bach C, Gilch S, Rost R, Greenwood AD, Horsch M, Hajj GN, Brodesser S, Facius A, Schadler S, Sandhoff K, Beckers J, Leib-Mosch C, Schatzl HM, Vorberg I. Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells. J Biol Chem. 2009 Jan 01; 284:31260-9. doi: 10.1074/jbc.M109.004382
Krammer C, Kryndushkin D, Suhre MH, Kremmer E, Hofmann A, Pfeifer A, Scheibel T, Wickner RB, Schatzl HM, Vorberg I. The yeast Sup35NM domain propagates as a prion in mammalian cells. Proc Natl Acad Sci U S A. 2009 Jan 01; 106:462-7. doi: 10.1073/pnas.0811571106
Maas E, Geissen M, Groschup MH, Rost R, Onodera T, Schatzl H, Vorberg IM. Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins. J Biol Chem. 2007 Jan 01; 282:18702-10. doi: 10.1074/jbc.M701309200
Priola SA, Vorberg I. Identification of possible animal origins of prion disease in human beings. Lancet. 2004 Jan 01; 363:2013-4. doi: 10.1016/S0140-6736(04)16487-8
Vorberg I, Raines A, Priola SA. Acute formation of protease-resistant prion protein does not always lead to persistent scrapie infection in vitro. J Biol Chem. 2004 Jan 01; 279:29218-25. doi: 10.1074/jbc.M402576200
Vorberg I, Raines A, Story B, Priola SA. Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents. J Infect Dis. 2004 Jan 01; 189:431-9. doi: 10.1086/381166
Vorberg I, Groschup MH, Pfaff E, Priola SA. Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform. J Virol. 2003 Jan 01; 77:2003-9.
Vorberg I, Priola SA. Molecular basis of scrapie strain glycoform variation. J Biol Chem. 2002 Jan 01; 277:36775-81. doi: 10.1074/jbc.M206865200
Vorberg I, Chan K, Priola SA. Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform. J Virol. 2001 Jan 01; 75:10024-32. doi: 10.1128/JVI.75.21.10024-10032.2001

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