Parkinson Genetik
Prof. Dr. Thomas Gasser
Leiter der Klinischen Forschung
am Standort Tübingen,
Gruppenleiter
Vorstandsmitglied des Hertie-Instituts für klinische Hirnforschung
Hoppe-Seyler-Str. 3
72076 Tübingen

thomas.gasser@dzne.de
 +49 7071 29-86529

Publikationen

Die vollständige Publikationsliste findet man hier.

David C. Schöndorf, Dina Ivanyuk, Pascale Baden, Alvaro Sanchez-Martinez, Silvia De Cicco, Cong Yu, Ivana Giunta, Lukas K. Schwarz, Gabriele Di Napoli, Vasiliki Panagiotakopoulou, Sigrun Nestel, Marcus Keatinge, Jan Pruszak, Oliver Bandmann, Bernd Heimrich, Thomas Gasser, Alexander J. Whitworth, Michela Deleidi. The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease. Cell Reports. 2018 Jun 04; 23:2976-2988. doi: 10.1016/j.celrep.2018.05.009
Aree Witoelar, Iris E. Jansen, Yunpeng Wang, Rahul S. Desikan, J. Raphael Gibbs, Cornelis Blauwendraat, Wesley K. Thompson, Dena G. Hernandez, Srdjan Djurovic, Andrew J. Schork, Francesco Bettella, David Ellinghaus, Andre Franke, Benedicte A. Lie, Linda K. McEvoy, Tom H. Karlsen, Suzanne Lesage, Huw R. Morris, Alexis Brice, Nicholas W. Wood, Peter Heutink, John Hardy, Andrew B. Singleton, Anders M. Dale, Thomas Gasser, et al. Genome-wide pleiotropy between Parkinson disease and autoimmune diseases. JAMA Neurology. 2017 Jun 30; 74:780-792. doi: 10.1001/jamaneurol.2017.0469
Fitzgerald JC, Zimprich A, Berrio DAC, Schindler KM, Maurer B, Schulte C, Bus C, Hauser AK, Kubler M, Lewin R, Bobbili DR, Schwarz LM, Vartholomaiou E, Brockmann K, Wust R, Madlung J, Nordheim A, Riess O, Martins LM, Glaab E, May P, Schenke-Layland K, Picard D, Sharma M, Gasser T, Kruger R. Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease. Brain. 2017 Jan 01; 140 doi: 10.1093/brain/awx202
Postuma RB, Berg D, Adler CH, Bloem BR, Chan P, Deuschl G, Gasser T, Goetz CG, Halliday G, Joseph L, Lang AE, Liepelt-Scarfone I, Litvan I, Marek K, Oertel W, Olanow CW, Poewe W, Stern M. The new definition and diagnostic criteria of Parkinson's disease. Lancet Neurol. 2016 Jan 01; 15:546-8. doi: 10.1016/s1474-4422(16)00116-2
Gasser T. Personalized Medicine Approaches in Parkinson's Disease: The Genetic Perspective. J Parkinsons Dis. 2016 Jan 01; 6:699-701. doi: 10.3233/jpd-160876
Gasser T. Usefulness of Genetic Testing in PD and PD Trials: A Balanced Review. J Parkinsons Dis. 2015 Jan 01; 5:209-15. doi: 10.3233/jpd-140507
David C. Schöndorf, Massimo Aureli, Fiona E. McAllister, Christopher J. Hindley, Florian Mayer, Benjamin Schmid, S. Pablo Sardi, Manuela Valsecchi, Susanna Hoffmann, Lukas Kristoffer Schwarz, Ulrike Hedrich, Daniela Berg, Lamya S. Shihabuddin, Jing Hu, Jan Pruszak, Steven P. Gygi, Sandro Sonnino, Thomas Gasser, Michela Deleidi. IPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis. Nature Communications. 2014 Jun 05; 5 doi: 10.1038/ncomms5028
Katja Lohmann, Alexander Schmidt, Arne Schillert, Susen Winkler, Alberto Albanese, Frank Baas, Anna Rita Bentivoglio, Friederike Borngräber, Norbert Brüggemann, Giovanni Defazio, Francesca Del Sorbo, Günther Deuschl, Mark J. Edwards, Thomas Gasser, Pilar Gómez-Garre, Julia Graf, Justus L. Groen, Anne Grünewald, Johann Hagenah, Claudia Hemmelmann, Hans-Christian Jabusch, Ryuji Kaji, Meike Kasten, Hideshi Kawakami, Vladimir S. Kostic, Maria Liguori, Pablo Mir, Alexander Münchau, Felicia Ricchiuti, Stefan Schreiber, Katharina Siegesmund, Marina Svetel, Marina A.J. Tijssen, Enza Maria Valente, Ana Westenberger, Kirsten E. Zeuner, Simone Zittel, Eckart Altenmüller, Andreas Ziegler, Christine Klein. Genome-wide association study in musician's dystonia: A risk variant at the arylsulfatase G locus?. Movement Disorders. 2013 Dec 31; 29:921-927. doi: 10.1002/mds.25791
Sidransky E, Nalls MA, Aasly JO, Aharon-Peretz J, Annesi G, Barbosa ER, Bar-Shira A, Berg D, Bras J, Brice A, Chen CM, Clark LN, Condroyer C, De Marco EV, Durr A, Eblan MJ, Fahn S, Farrer MJ, Fung HC, Gan-Or Z, Gasser T, Gershoni-Baruch R, Giladi N, Griffith A, Gurevich T, Januario C, Kropp P, Lang AE, Lee-Chen GJ, Lesage S, Marder K, Mata IF, Mirelman A, Mitsui J, Mizuta I, Nicoletti G, Oliveira C, Ottman R, Orr-Urtreger A, Pereira LV, Quattrone A, Rogaeva E, Rolfs A, Rosenbaum H, Rozenberg R, Samii A, Samaddar T, Schulte C, Sharma M, Singleton A, et al. Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease. N Engl J Med. 2009 Jan 01; 361:1651-61. doi: 10.1056/NEJMoa0901281
Mueller JC, Fuchs J, Hofer A, Zimprich A, Lichtner P, Illig T, Berg D, Wullner U, Meitinger T, Gasser T. Multiple regions of alpha-synuclein are associated with Parkinson's disease. Ann Neurol. 2005 Jan 01; 57:535-41. doi: 10.1002/ana.20438
erg D, Schweitzer KJ, Leitner P, Zimprich A, Lichtner P, Belcredi P, Brussel T, Schulte C, Maass S, Nagele T, Wszolek ZK, Gasser T. Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease. Brain. 2005 Jan 01; 128:3000-11. doi: 10.1093/brain/awh666

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