Ex vivo Modelle
Dr. Sabina Tahirovic
Gruppenleiterin
Feodor-Lynen-Str. 17
81377 München

sabina.tahirovic@dzne.de
 +49 89 4400-46438

Publikationen

Die vollständige Publikationsliste findet man hier.

Fargol Mazaheri, Nicolas Snaidero, Gernot Kleinberger, Charlotte Madore, Anna Daria, Georg Werner, Susanne Krasemann, Anja Capell, Dietrich Trümbach, Wolfgang Wurst, Bettina Brunner, Sebastian Bultmann, Sabina Tahirovic, Martin Kerschensteiner, Thomas Misgeld, Oleg Butovsky, Christian Haass. TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury. EMBO Reports. 2017 Jun 30; 18:1186-1198. doi: 10.15252/embr.201743922
Anna Daria, Alessio Colombo, Gemma Llovera, Heike Hampel, Michael Willem, Arthur Liesz, Christian Haass, Sabina Tahirovic. Young microglia restore amyloid plaque clearance of aged microglia. EMBO Journal. 2017 Feb 28; 36:583-603. doi: 10.15252/embj.201694591
Michael Willem, Sabina Tahirovic, Marc Aurel Busche, Saak V. Ovsepian, Magda Chafai, Scherazad Kootar, Daniel Hornburg, Lewis D.B. Evans, Steven Moore, Anna Daria, Heike Hampel, Veronika Müller, Camilla Giudici, Brigitte Nuscher, Andrea Wenninger-Weinzierl, Elisabeth Kremmer, Michael T. Heneka, Dietmar R. Thal, Vilmantas Giedraitis, Lars Lannfelt, Ulrike Müller, Frederick J. Livesey, Felix Meissner, Jochen Herms, Arthur Konnerth, Hélène Marie, Christian Haass. σ-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015 Oct 14; 526:443-447. doi: 10.1038/nature14864
Bachhuber T, Katzmarski N, McCarter JF, Loreth D, Tahirovic S, Kamp F, Abou-Ajram C, Nuscher B, Serrano-Pozo A, Müller A, Prinz M, Steiner H, Hyman BT, Haass C, Meyer-Luehmann M. Inhibition of Amyloid-beta Plaque Formation by alpha-Synuclein. Nat Med. 2015 Jul 01; 21:802-7. doi: 10.1038/nm.3885
Gernot Kleinberger, Yoshinori Yamanishi, Marc Suárez-Calvet, Eva Czirr, Ebba Lohmann, Elise Cuyvers, Hanne Struyfs, Nadine Pettkus, Andrea Wenninger-Weinzierl, Fargol Mazaheri, Sabina Tahirovic, Alberto Lleó, Daniel Alcolea, Juan Fortea, Michael Willem, Sven Lammich, José L. Molinuevo, Raquel Sánchez-Valle, Anna Antonell, Alfredo Ramirez, Michael T. Heneka, Kristel Sleegers, Julie Van Der Zee, Jean-Jacques Martin, Sebastiaan Engelborghs, Asli Demirtas-Tatlidede, Henrik Zetterberg, Christine Van Broeckhoven, Hakan Gurvit, Tony Wyss-Coray, John Hardy, Marco Colonna, Christian Haass. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science Translational Medicine. 2014 Jul 01; 6 doi: 10.1126/scitranslmed.3009093
Julia K. Götzl, Kohji Mori, Markus Damme, Katrin Fellerer, Sabina Tahirovic, Gernot Kleinberger, Jonathan Janssens, Julie Van Der Zee, Christina M. Lang, Elisabeth Kremmer, Jean-Jacques Martin, Sebastiaan Engelborghs, Hans A. Kretzschmar, Thomas Arzberger, Christine Van Broeckhoven, Christian Haass, Anja Capell. Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis. Acta Neuropathologica. 2013 Dec 31; 127:845-860. doi: 10.1007/s00401-014-1262-6
Benjamin M. Schwenk, Christina M. Lang, Sebastian Hogl, Sabina Tahirovic, Denise Orozco, Kristin Rentzsch, Stefan F. Lichtenthaler, Casper C. Hoogenraad, Anja Capell, Christian Haass, Dieter Edbauer. The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes. EMBO Journal. 2014 Mar 02; 33:450-467. doi: 10.1002/embj.201385857
Kevin C. Flynn, Farida Hellal, Dorothee Neukirchen, Sonja Jacob, Sabina Tahirovic, Sebastian Dupraz, Sina Stern, Boyan K. Garvalov, Christine Gurniak, Alisa E. Shaw, Liane Meyn, Roland Wedlich-Söldner, James R. Bamburg, J. Victor Small, Walter Witke, Frank Bradke. ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain. Neuron. 2012 Dec 19; 76:1091-1107. doi: 10.1016/j.neuron.2012.09.038
Denise Orozco, Sabina Tahirovic, Kristin Rentzsch, Benjamin M. Schwenk, Christian Haass, Dieter Edbauer. Loss of fused in sarcoma (FUS) promotes pathological Tau splicing. EMBO Reports. 2012 Jul 31; 13:759-764. doi: 10.1038/embor.2012.90
Martina Malnar, Marko Kosicek, Ana Lisica, Melanija Posavec, Ana Krolo, Jasenka Njavro, Damir Omerbasic, Sabina Tahirovic, Silva Hecimovic. Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2012 Jul 31; 1822:1270-1283. doi: 10.1016/j.bbadis.2012.04.002

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