Altersbedingte Veränderungen der Synapsenstruktur und -funktion
Prof. Dr. Stephan Sigrist
Gruppenleiter
Takustr. 6
14195 Berlin

stephan.sigrist@dzne.de
 +49 30 838-56940

Publikationen

Die vollständige Publikationsliste findet man hier.

Bhukel A, Madeo F, Sigrist SJ. Spermidine boosts autophagy to protect from synapse aging. Autophagy. 2017 Feb 01; 13:444-445. doi: 10.1080/15548627.2016.1265193
Grauel MK, Maglione M, Reddy-Alla S, Willmes CG, Brockmann MM, Trimbuch T, Rosenmund T, Pangalos M, Vardar G, Stumpf A, Walter AM, Rost BR, Eickholt BJ, Haucke V, Schmitz D, Sigrist SJ, Rosenmund C. RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses. Proc Natl Acad Sci U S A. 2016 Oct 11; 113:11615-11620. doi: 10.1073/pnas.1605256113
Gupta VK, Pech U, Bhukel A, Fulterer A, Ender A, Mauermann SF, Andlauer TF, Antwi-Adjei E, Beuschel C, Thriene K, Maglione M, Quentin C, Bushow R, Schwärzel M, Mielke T, Madeo F, Dengjel J, Fiala A, Sigrist SJ. Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release. PLoS Biol. 2016 Sep 29; 14:e1002563. doi: 10.1371/journal.pbio.1002563
4. Sigrist SJ, Carmona-Gutierrez D, Gupta VK, Bhukel A, Mertel S, Eisenberg T, Madeo F. Spermidine-triggered autophagy ameliorates memory during aging. Autophagy. 2014 Jan 01; 10:178-9. doi: 10.4161/auto.26918
Gupta VK, Scheunemann L, Eisenberg T, Mertel S, Bhukel A, Koemans TS, Kramer JM, Liu KS, Schroeder S, Stunnenberg HG, Sinner F, Magnes C, Pieber TR, Dipt S, Fiala A, Schenck A, Schwaerzel M, Madeo F, Sigrist SJ. Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner. Nat Neurosci. 2013 Oct 01; 16:1453-60. doi: 10.1038/nn.3512

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