Molekulare und zelluläre Kognition
Priv.-Doz. Dr. Dan Ehninger
Gruppenleiter
Sigmund-Freud-Str. 27
53127 Bonn

dan.ehninger@dzne.de
 +49 228 43302-530

Publikationen

Die vollständige Publikationsliste findet man hier.

Kan Xie, Devon P. Ryan, Brandon L. Pearson, Kristin S. Henzel, Frauke Neff, Ramon O. Vidal, Magali Hennion, Isabelle Lehmann, Melvin Schleif, Susanne Schröder, Thure Adler, Birgit Rathkolb, Jan Rozman, Anna-Lena Schütz, Cornelia Prehn, Michel E. Mickael, Marco Weiergräber, Jerzy Adamski, Dirk H. Busch, Gerhard Ehninger, Anna Matynia, Walker S. Jackson, Eckhard Wolf, Helmut Fuchs, Valerie Gailus-Durner, Stefan Bonn, Martin Hrabě de Angelis, Dan Ehninger. Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice. Proc Natl Acad Sci USA. 2018 Feb 21; doi: 10.1073/pnas.1707337115
Ilaria Bellantuono, Rafael de Cabo, Dan Ehninger, Adelaide Fernandez, Susan E. Howlett, Ralph Müller, Paul K. Potter, Anne-Ulrike Trendelenburg, Jose L. Trejo, Roosmarijn E. Vandenbroucke, Ronald van Os, Natal A. W. van Riel. Find drugs that delay many diseases of old age. Nature. 2018 Feb 15; 554:293-295. doi: 10.1038/d41586-018-01668-0
Kan Xie, Frauke Neff, Astrid Markert, Jan Rozman, Juan Antonio Aguilar-Pimentel, Oana Veronica Amarie, Lore Becker, Robert Brommage, Lillian Garrett, Kristin S. Henzel, Sabine M. Hölter, Dirk Janik, Isabelle Lehmann, Kristin Moreth, Brandon L. Pearson, Ildiko Racz, Birgit Rathkolb, Devon P. Ryan, Susanne Schröder, Irina Treise, Raffi Bekeredjian, Dirk H. Busch, Jochen Graw, Gerhard Ehninger, Martin Klingenspor, Thomas Klopstock, Markus Ollert, Michael Sandholzer, Carsten Schmidt-Weber, Marco Weiergräber, Eckhard Wolf, Wolfgang Wurst, Andreas Zimmer, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabě De Angelis, Dan Ehninger. Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice. Nat Commun. 2017 Nov 30; 8 doi: 10.1038/s41467-017-00178-3
Kristin S. Henzel, Devon P. Ryan, Susanne Schröder, Marco Weiergräber, Dan Ehninger. High-dose maternal folic acid supplementation before conception impairs reversal learning in offspring mice. Sci Rep. 2017 Nov 30; 7 doi: 10.1038/s41598-017-03158-1
Ryan, Henzel, Pearson, Siwek, Papazoglou, Guo, Paesler, Yu, Müller, Xie, Schröder, Becker, Garrett, Hölter, Neff, Rácz, Rathkolb, Rozman, Ehninger, Klingenspor, Klopstock, Wolf, Wurst, Zimmer, Fuchs, Gailus-Durner, Hrabě De Angelis, Sidiropoulou, Weiergräber, Zhou, Ehninger. A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice. Mol Psychiatry. 2018 Apr 30; 23:1345-1355. doi: 10.1038/mp.2017.53
Yong-Seok Lee, Dan Ehninger, Miou Zhou, Jun-Young Oh, Minkyung Kang, Chuljung Kwak, Hyun-Hee Ryu, Delana Butz, Toshiyuki Araki, Ying Cai, Balaji, Yoshitake Sano, Christine I Nam, Hyong Kyu Kim, Bong-Kiun Kaang, Corinna Burger, Benjamin G. Neel, Alcino J. Silva. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci. 2013 Dec 31; 17:1736-1743. doi: 10.1038/nn.3863
Devon Patrick Ryan, Dan Ehninger. Bison: Bisulfite alignment on nodes of a cluster. BMC Bioinformatics. 2013 Dec 31; 15 doi: 10.1186/1471-2105-15-337
Dan Ehninger, Frauke Neff, Kan Xie. Longevity, aging and rapamycin. Cell Mol Life Sci. 2014 Oct 31; 71:4325-4346. doi: 10.1007/s00018-014-1677-1
Frauke Neff, Diana Flores-Dominguez, Devon P. Ryan, Marion Horsch, Susanne Schröder, Thure Adler, Luciana Caminha Afonso, Juan Antonio Aguilar-Pimentel, Lore Becker, Lillian Garrett, Wolfgang Hans, Moritz M. Hettich, Richard Holtmeier, Sabine M. Hölter, Kristin Moreth, Cornelia Prehn, Oliver Puk, Ildikó Rácz, Birgit Rathkolb, Jan Rozman, Beatrix Naton, Rainer Ordemann, Jerzy Adamski, Johannes Beckers, Raffi Bekeredjian, Dirk H. Busch, Gerhard Ehninger, Jochen Graw, Heinz Höfler, Martin Klingenspor, Thomas Klopstock, Markus Ollert, Jörg Stypmann, Eckhard Wolf, Wolfgang Wurst, Andreas Zimmer, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabe De Angelis, Dan Ehninger. Rapamycin extends murine lifespan but has limited effects on aging. J Clin Invest. 2013 Jul 31; 123:3272-3291. doi: 10.1172/JCI67674
Miou Zhou, Weidong Li, Shan Huang, Juan Song, Ju Young Kim, Xiaoli Tian, Eunchai Kang, Yoshitake Sano, Cindy Liu, Balaji, Shumin Wu, Yu Zhou, Ying Zhou, Sherveen N. Parivash, Dan Ehninger, Lin He, Hongjun Song, Guo-li Ming, Alcino J. Silva. MTOR Inhibition Ameliorates Cognitive and Affective Deficits Caused by Disc1 Knockdown in Adult-Born Dentate Granule Neurons. Neuron. 2013 Feb 19; 77:647-654. doi: 10.1016/j.neuron.2012.12.033
Ehninger, Sano, De Vries, Dies, Franz, Geschwind, Kaur, Lee, Li, Lowe, Nakagawa, Sahin, Smith, Whittemore, Silva. Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice. Mol Psychiatry. 2011 Dec 31; 17:62-70. doi: 10.1038/mp.2010.115
Carrie Shilyansky, Katherine H. Karlsgodt, Damian M. Cummings, Kyriaki Sidiropoulou, Molly Hardt, Alex S. James, Dan Ehninger, Carrie E. Bearden , Panayiota Poirazi, J. David Jentsch, Tyrone D. Cannon, Michael S. Levine, Alcino J. Silva. Neurofibromin regulates corticostriatal inhibitory networks during working memory performance. Proc Natl Acad Sci USA. 2010 Jul 20; 107:13141-6. doi: 10.1073/pnas.1004829107
Dan Ehninger, Alcino J. Silva. Genetics and neuropsychiatric disorders: treatment during adulthood. Nat Med. 2009 Aug 01; 15:849-50. doi: 10.1038/nm0809-849
Dan Ehninger, Weidong Li, Kevin Fox, Michael P. Stryker, Alcino J. Silva. Reversing neurodevelopmental disorders in adults. Neuron. 2008 Dec 26; 60:950-60. doi: 10.1016/j.neuron.2008.12.007
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J. Kwiatkowski, Vijaya Ramesh, Alcino J. Silva. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med. 2008 Aug 01; 14:843-8. doi: 10.1038/nm1788

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