Neuroprotektive Mechanismen
Prof. Dr. Donato Di Monte
Gruppenleiter
Sigmund-Freud-Str. 27
53127 Bonn

donato.dimonte@dzne.de
 +49 228 43302-650

Publikationen

Die vollständige Publikationsliste findet man hier.

Ayse Ulusoy, Robert J. Phillips, Michael Helwig, Michael Klinkenberg, Terry L. Powley, Donato A. Di Monte. Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections. Acta Neuropathologica. 2017 Feb 28; 133:381-393. doi: 10.1007/s00401-016-1661-y
Anna Migdalska-Richards, Michal Wegrzynowicz, Raffaella Rusconi, Giulio Deangeli, Donato A. Di Monte, Maria G. Spillantini, Anthony H. V. Schapira. The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice. Brain. 2016 Dec 31; 140:2706-2721. doi: 10.1093/brain/awx221
Tate CC, Chou VP, Campos C, Moalem AS, Di Monte DA, McGrogan M, Case CC, Manning-Bog AB. Mesenchymal stromal SB623 cell implantation mitigates nigrostriatal dopaminergic damage in a mouse model of Parkinson's disease. J Tissue Eng Regen Med. 2017 Jul 01; 11:1835-1843. doi: 10.1002/term.2081
Michael Helwig, Michael Klinkenberg, Raffaella Rusconi, Ruth E. Musgrove, Nour K. Majbour, Omar M. A. El-Agnaf, Ayse Ulusoy, Donato A. Di Monte. Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice. Brain. 2016 Feb 29; 139:856-870. doi: 10.1093/brain/awv376
Anna Kabanova, Milan Pabst, Markus Lorkowski, Oliver Braganza, Anne Boehlen, Negar Nikbakht, Leonie Pothmann, Ankita R. Vaswani, Ruth Musgrove, Donato A. Di Monte, Magdalena Sauvage, Heinz Beck, Sandra Blaess. Function and developmental origin of a mesocortical inhibitory circuit. Nature Neuroscience. 2014 Dec 31; 18:872-882. doi: 10.1038/nn.4020
Ulusoy A, Musgrove RE, Rusconi R, Klinkenberg M, Helwig M, Schneider A, Di Monte DA. Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury. Acta Neuropathol Commun. 2015 Mar 24; 3:13. doi: 10.1186/s40478-015-0198-y
Bodea LG, Wang Y, Linnartz-Gerlach B, Kopatz J, Sinkkonen L, Musgrove R, Kaoma T, Muller A, Vallar L, Di Monte DA, Balling R, Neumann H. Neurodegeneration by activation of the microglial complement-phagosome pathway. J Neurosci. 2014 Jun 18; 34:8546-56. doi: 10.1523/JNEUROSCI.5002-13.2014
Pérez-Revuelta, Hettich, Ciociaro, Rotermund, Kahle, Krauss, Di Monte. Metformin lowers Ser-129 phosphorylated α-synuclein levels via mTOR-dependent protein phosphatase 2A activation. Cell Death and Disease. 2013 Dec 31; 5 doi: 10.1038/cddis.2014.175
Ayse Ulusoy, Raffaella Rusconi, Blanca I. Pérez-Revuelta, Ruth E. Musgrove, Michael Helwig, Bettina Winzen-Reichert, Donato A. Di Monte. Caudo-rostral brain spreading of α-synuclein through vagal connections. EMBO Molecular Medicine. 2013 Jun 30; 5:1051-1059. doi: 10.1002/emmm.201302475
McCormack, Mak, Di Monte. Increased a-synuclein phosphorylation and nitration in the aging primate substantia nigra. Cell Death and Disease. 2012 May 23; 3 doi: 10.1038/cddis.2012.50
Alison L. McCormack, Sally K. Mak, Jaimie M. Henderson, David Bumcrot, Matthew J. Farrer, Donato A. Di Monte. α-synuclein suppression by targeted small interfering rna in the primate substantia nigra. PLoS ONE. 2010 Oct 18; 5 doi: 10.1371/journal.pone.0012122
Mak SK, McCormack AL, Manning-Bog AB, Cuervo AM, Di Monte DA. Lysosomal degradation of alpha-synuclein in vivo. J Biol Chem. 2010 Apr 30; 285:13621-9. doi: 10.1074/jbc.M109.074617

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