SAMRI - Small Animal MRI Facility

We offer access to the platform for you to pursue non-invasive in vivo imaging projects after training and also provide consultancy services to level up your research project. SAMRI operates on a fee for service model. Booking of instruments and assistance is possible with MARIE Platform.

Animal Imaging Tools are offered at a cost. Booking is available in MARIE Platform.

• Bruker Biospec 11.7T small animal MRI
• IVIS Lumina II
• ParaVision 7.0 for MR image and data analysis
• Living Image software for IVIS data analysis

Consultancy

Our consultancy services include:

• MR study and protocol design
• Sequence development
• MR acquisitions
• Training for independent MR experiments
• Data analysis
• IVIS Lumina II imaging and image analysis

In vivo non-invasive imaging technologies in detail:

MRI

• Bruker Biospec 11.7T small animal MRI
• Cryoprobe
• 1H mouse brain resonator (72 mm)
• 1H rat brain array coil
• 1H volume coil
• 1H Planar surface coil
• Rat and mouse Beds
• Small animal monitoring system (SA instruments Inc.) to monitor respiration, temperature and ECG during experiments. This can also be used for triggering and gating during cardiac studies.
• Table-top gas anesthesia system (Isoflurane)

In vivo fluorescence

• IVIS Lumina II imaging system
• Integrated gas anesthesia system (Isoflurane)

MRI can be used for:

In-vivo

• Neuro imaging 
  • Anatomical imaging for morphometry, volumetry, phenotyping and lesion detection
  • Parametric evaluation (e.g., iron load in Parkinson’s disease model, neuroinflammation)
  • Diffusion weighted Imaging and fiber tractography for white matter integrity
  • MR spectroscopy for inflammation and brain metabolite concentration
• Whole body imaging
• Spinal cord imaging
• Cardiac imaging

Tissue imaging

Cellular imaging

• Cell migration tracking (with labelling)
• Cell culture imaging

IVIS Lumina:

Quantitative fluorescence imaging 

Bioluminescence imaging

1. Contact Cornelia Hesse
2. Discuss the project and requirements
3. Agree and sign user rules
4. Depending on the background, user might need an introduction.

Schedule an introduction at samri(at)dzne.de.

General terms of use for core facilities.

For pricing information, please contact Cornelia Hesse.