Site Munich
Brain diseases such as Alzheimer’s, Parkinson’s, and frontotemporal dementia have one thing in common despite different symptoms: The nerve cells atrophy and die. With this in mind, the DZNE site in Munich is researching the mechanisms of nerve-damaging processes in order to pave the way for new approaches in prevention, diagnosis, and treatment. To this end, the scientists are investigating a variety of phenomena such as inflammatory processes in the brain, circulatory disorders, and disease processes that are fatally triggered by the body’s own proteins.
Through human clinical studies, the Munich-based experts are conducting research to improve the early detection of dementia and movement disorders and to develop new therapeutic measures. This includes the search for “biomarkers,” which are biological parameters (such as specific measured values in the blood or cerebrospinal fluid) that help to detect a disease and assess its future progression. Clinical research in Munich also has a special focus in addition to these efforts; namely, the rare, hereditary form of Alzheimer’s disease.
Address
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)
Feodor-Lynen-Strasse 17
81377 Munich
Working Groups
Cell Biology of Neurodegeneration
Prof. Dr. Dieter Edbauer
Molecular Neurodegeneration
Prof. Dr. Dr. h.c. Christian Haass
Translational Brain Research (Focus Animal Models)
Prof. Dr. Jochen Herms
Neuroproteomics
Prof. Dr. Stefan Lichtenthaler
Ex vivo models
Dr. Sabina Tahirovic
Core Facility
Monoclonal Antibodies
Dr. Regina Feederle
Zebrafish Models
Dr. Bettina Schmid
Genome Engineering
Prof. Dr. Wolfgang Wurst
Cooperation Units
Neuronal Cell Biology
Prof. Dr. Thomas Misgeld
Molecular Neurobiology
Prof. Dr. Mikael Simons
Biochemistry of γ-Secretase
Prof. Dr. Harald Steiner
