Site Munich

Brain diseases such as Alzheimer’s, Parkinson’s, and frontotemporal dementia have one thing in common despite different symptoms: The nerve cells atrophy and die. With this in mind, the DZNE site in Munich is researching the mechanisms of nerve-damaging processes in order to pave the way for new approaches in prevention, diagnosis, and treatment. To this end, the scientists are investigating a variety of phenomena such as inflammatory processes in the brain, circulatory disorders, and disease processes that are fatally triggered by the body’s own proteins.

Through human clinical studies, the Munich-based experts are conducting research to improve the early detection of dementia and movement disorders and to develop new therapeutic measures. This includes the search for “biomarkers,” which are biological parameters (such as specific measured values in the blood or cerebrospinal fluid) that help to detect a disease and assess its future progression. Clinical research in Munich also has a special focus in addition to these efforts; namely, the rare, hereditary form of Alzheimer’s disease.

Working Groups

Translational Disease Modeling
Prof. Dr. Lena Burbulla

Cell Biology of Neurodegeneration
Prof. Dr. Dieter Edbauer 

Molecular Neurodegeneration
Prof. Dr. Dr. h.c. Christian Haass

Translational Brain Research (Focus Animal Models)
Prof. Dr. Jochen Herms

Prof. Dr. Stefan Lichtenthaler

Neuroimmunology and Neurodegenerative Disease
Prof. Dr. Jonas Neher

Zebrafish Models
Dr. Bettina Schmid

Molecular Neurobiology
Prof. Dr. Mikael Simons

Biochemistry of γ-Secretase
Prof. Dr. Harald Steiner

Juvenile Neurodegeneration
Dr. Sabina Tahirovic

Adaptive immunity in neurodegeneration
Dr. Qihui Zhou

Core Facility

Monoclonal Antibodies
Dr. Regina Feederle

Genome Engineering
Prof. Dr. Wolfgang Wurst

Cooperation Units

Neuronal Cell Biology
Prof. Dr. Thomas Misgeld

Associated Investigators

Clinical Neurodegeneration
Prof. Dr. Johannes Levin

Translational Neurodegeneration
Prof. Dr. Günter Höglinger

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