DANCER / DANCER-FTD / DANCER-PSP

Degeneration Controls and Relatives

Establishment of a Recruitment Pool of Potential Study Participants, of Realtives and a Control Group for DZNE Studies

Background and aims

Clinical studies are conducted at the DZNE's German sites in cooperation with university hospitals. One focus of these studies is the identification of early, specific changes, e. g. in the blood, so that the diagnosis of a neurodegenerative disease such as dementia or Parkinson's disease can be made at a very early stage. This enables a better understanding of the diseases and supports the development of new therapies.

In order to evaluate the study results of neurologically affected patients, comparative studies with the following groups of people are necessary:

  • Relatives of neurologically affected patients with e.g. Alzheimer's, Parkinson's, Frontotemporal Dementia (FTD), Progressive Supranuclear Paresis (PSP)
  • Interested persons without diagnosis of a neurodegenerative disease
  • Persons undergoing medical treatment with other complaints in one of the cooperating clinics

Course of the study

Prior to the study, the study physician will inform you about the examinations and coordinate the course of the study with you. In the course of the interview you will of course have the opportunity to ask questions.

After agreeing to participate in the study, proceed:

  • a query about medical history and medications
  • a 30-minute study on memory, concentration and mood
  • an indicative neurological examination
  • blood samples for the determination of bio-chemical and genetic markers

In addition, further examinations give us insights into the development of neurodegenerative diseases. For each of these examinations the consent can be given individually.

The examinations include:

  • further examinations of cognitive performance (e. g. memory performance, action planning, word fluency)
  • investigations on motor skills (e. g. gait analysis, physical activity, eye movements)
  • magnetic resonance imaging of the brain (3T-MRI)
  • consent to interview a person around you about your everyday behaviour

The examinations are usually carried out once a year and last 2-4 hours.

A full set of information about the study can be downloaded here (in German only): Flyer DANCER

Principle Investigator: Prof. Dr. Thomas Klockgether
Start of the study: 2015
Status: multi centric, ongoing, recruiting active

Study Coordination / Project Management

Dr. Daniel Hoffmann
 daniel.hoffmann@dzne.de
 +49 228 43302-837
 +49 228 43302-812

Participating sites

Berlin

DZNE
Charité – Campus Benjamin Franklin, Clinic for Psychiatry and Psychotherapy
Local principle investigator:
Priv.-Doz. Dr. Oliver Peters
Local contact:
+49 30 450-540077

DZNE
Charité - Campus Charité Mitte, Dept. Neuropsychiaty & Lab for Moleculare Psychiatry
Local principle investigator:
Prof. Dr. Josef Priller
Local contact:
+49 30 450-617239

DZNE
Charité - Campus Virchow-Klinikum, Centrum Neurology, Neurosurgery and Psychiatry
Local principle investigator:
Dr. Andrea A. Kühn
Prof. Matthias Endres
Local contact:
+49 30 450-660203

Bonn

DZNE
Universitätsklinikum Bonn
- Klinik und Poliklinik für Neurologie
Local principle investigator:
Prof. Dr. Thomas Klockgether
Prof. Dr. Ullrich Wüllner
Local contact:
+49 228 287-14431

DZNE
Zentrum für Klinische Forschung
Local principle investigator:
Dr. Annika Spottke
Local contact:
+49 228 43302-810

DZNE
Universitätsklinikum Bonn - Klinik für Neurodegenerative Erkrankungen und Gerontopsychiatrie
Local principle investigator:
Prof. Dr. Anja Schneider
Prof. Dr. Michael Heneka
Prof. Dr. Michael Wagner
Local contact:
+49 228 287-16367

Dresden

DZNE
Universitätsklinikum TU Dresden 
- Klinik und Poliklinik für Psychiatrie und Psychotherapie
Local principle investigator: 
Prof. Dr. Markus Donix​​​​​​​
Local contact:
+49 351 458-7136

DZNE
Universitätsklinikum TU Dresden 
- Klinik und Poliklinik für Neurologie
Local principle investigator:
Prof. Dr. Alexander Storch
Local contact:
+49 351 458-2524

Göttingen

DZNE
Universitätsmedizin Göttingen
 - Klinik für Psychiatrie und Psychotherapie
Local principle investigator:
Prof. Dr. Jens Wiltfang
Dr. Sarah Trost
Local contact:
+49 551 39- 66601
+49 551 39- 66610

DZNE
Universitätsmedizin Göttingen
- Abteilung Neurologie
Local principle investigator:
Prof. Dr. Inga Zerr
Prof. Dr. Mathias Bähr
Local contact:
+49 551 39-8401

Cologne

DZNE
Universitätsklinikum Köln
 – Klinik und Poliklinik für Psychiatrie und Psychotherapie
Local principle investigator: 
Prof. Dr. Frank Jessen
Local contact:
+49 221 478-32888

DZNE
Universitätsklinikum Köln
 – Klinik und Poliklinik für Neurologie
Local principle investigator: 
Prof. Dr. Thilo von Eimeren
Local contact:
+49 221 478-98842

Magdeburg

DZNE
Otto-von-Guericke-Universität Magdeburg
- Institut für Kognitive Neurologie und Demenzforschung
Local principle investigator:
Prof. Dr. Emrah Düzel
Prof. Dr. Notger Müller
Prof. Dr. Stefan Vielhaber
Prof. Dr. Thomas Wolbers
Local contact:
+ 49 391 6724-524
+ 49 391 6724-555

Munich

DZNE
Klinikum der Universität München
- Institut für Schlaganfall- und Demenzforschung (ISD)
Local principle investigator:
Prof. Dr. Martin Dichgans
PD Dr. Katharina Bürger
Local contact:
+49 89 4400-46051
+49 89 4400-46052

DZNE
Klinikum der Universität München
 - Klinik und Poliklinik für Psychiatrie und Psychotherapie
Local principle investigator: 
Prof. Dr. Robert Perneczky 
Local contact:
+49 89 4400-53439

DZNE
Klinikum rechts der Isar der Technischen Universität München
- Neurologische Klinik und Poliklinik im Neuro-Kopf-Zentrum
und
Klinische DZNE Studieneinheit am Zentrum für Schlaganfall- und Demenzforschung
Local principle investigator:
Prof. Dr. Günter Höglinger
Local contact: 
+49 89 4400-46452
+49 89 4400-46455

DZNE
Friedrich-Baur-Institut an der Neurologischen Klinik

Local principle investigator:
Prof. Dr. Thomas Klopstock
Local contact:
+49 89 / 4400-57400

DZNE
Klinikum der Universität München
- Neurologische Klinik und Poliklinik
Local principle investigator:
PD Dr. Johannes Levin
Local contact:
+49 89 4400-46458
+49 89 4400-46467

Rostock/Greifswald

DZNE
Universitätsklinikum Rostock
 - Klinik und Poliklinik für Psychosomatik und Psychotherapeutische Medizin, Zentrum für Nervenheilkunde
Local principle investigator:
Prof. Stefan Teipel
Local contact:
+49 381 4949-628

DZNE
Universitätsklinikum Rostock
- Klinik und Poliklinik für Neurologie
Local principle investigator:
PD Dr. Christoph Kamm
Prof. Dr. Johannes Prudlo
Prof. Dr. Alexander Storch
Local contact:
+49 381 4949-170

Tübingen

DZNE
Universitätsklinikum Tübingen 
- Klinik für Psychiatrie und Psychotherapie 
Local principle investigator: 
Prof. Dr. Christoph Laske
Local contact:
+49 7071 298-2344

DZNE
Universitätsklinikum Tübingen
- Zentrum für Neurologie, Abteilung Neurodegenerative Erkrankungen
Local principle investigator:
Prof. Dr. Thomas Gasser
Prof. Dr. Ludger Schoels
PD. Dr. Matthias Synofzik
Local contact:
+49 7071 298-5660

Info-Hotline

Thursdays 1:30-4:30 pm

Patients +49 800-7799001

(free of charge)

Professionals +49 180-779900

(9 Cent/Min. German landline, mobile and out of Germany possibly more expensive)

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