Vascular cognitive impairment & Post-stroke dementia
Prof. Dr. Martin Dichgans
Cooperation Unit Leader
Director of the Institute for Stroke and Dementia Research
Feodor-Lynen-Str. 17
81377 München

martin.dichgans@dzne.de
 +49 89 4400-46019

Areas of investigation/research focus

Reasearch lab:
Institute for Stroke and Dementia Research (ISD)

Currently, there is a focus on the following project areas:

  • Vascular cognitive impairment | Post-stroke dementia
  • Microvessels
  • Genetics
  • Imaging
  • Surrogate markers for clinical trials
  • Investigator-initiated trials
  • Animal models
  • Vascular mechanisms

The cooperation partner's homepage can be found here.

Key Publications

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S and Dichgans M, et al. Multi-ancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nat Genet. 2018 Apr 01; 50:524-537. doi: 10.1038/s41588-018-0058-3
Georgakis MK, Gill D, Rannikmäe K, Traylor M, Anderson CD, MEGASTROKE consortium of the International Stroke Genetics Consortium, Lee JM, Kamatani Y, Hopewell JC, Worrall BB, Bernhagen J, Sudlow CLM, Malik R, Dichgans M. Genetically Determined Levels of Circulating Cytokines and Risk of Stroke: Role of Monocyte Chemoattractant Protein-1. Circulation. 2019 Jan 18; 139:256-268. doi: 10.1161/CIRCULATIONAHA.118.035905
Malik R, Rannikmäe K, Traylor M, Georgakis MK, Sargurupremraj M, Markus HS, Hopewell JC, Debette S, Sudlow CLM, Dichgans M. Genome-wide meta-analysis identifies 3 novel loci associated with stroke. Ann Neurol. 2018 Dec 06; 84:934-939. doi: 10.1002/ana.25369
Steffen Tiedt, Marco Duering, Christian Barro, Asli Gizem Kaya, Julia Boeck, Felix J. Bode, Matthias Klein, Franziska Dorn, Benno Gesierich, Lars Kellert, Birgit Ertl-Wagner, Michael W. Goertler, Gabor C. Petzold, Jens Kuhle, Frank A. Wollenweber, Nils Peters, Martin Dichgans. Serum neurofilament light: A biomarker of neuroaxonal injury after ischemic stroke. Neurology. 2018 Oct 01; 91:e1338-e1347. doi: 10.1212/WNL.0000000000006282
Malik R, Dau T, Gonik M, Sivakumar A, Deredge D, Edeleva EV, Götzfried J, van der Laan SW, Dichgans M, et al.. A common coding variant in SERPINA1 increases the risk for large artery stroke. Proc Natl Acad Sci U S A. 2017 Apr 04; 114:3613-3618. doi: 10.1073/pnas.1616301114
Tiedt S, Prestel P, Kautzky V, Düring M,…, Malik R,…, Dichgans M. RNA -seq identifies circulating miR-125a-5p, miR-125b-5p and miR-143-3p as potential biomarkers for acute ischemic stroke. Circ Res. 2017 Jan 01; 121:970-80. doi: 10.1161/CIRCRESAHA.117.311572

Info-Hotline

Thursdays 1:30-4:30 pm

Patients +49 800-7799001

(free of charge)

Professionals +49 180-779900

(9 Cent/Min. German landline, mobile and out of Germany possibly more expensive)

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