ApoE Sleep

Influence of the Apolipoprotein-E Genotype on Brain Activity during Sleep and Wakefulness

Background and aims

In this study, simultaneous EEG/fMRI measurements are carried out on test persons while they are in a calm waking state and while they are asleep. The measurements are carried out on healthy test persons whose genotype has been determined to include the apolipoprotein-E (ApoE) gene. The aim is to study neurovascular (EEG-fMRI) coupling during various sleep phases, in its dependence on the ApoE genotype. In addition, potential relevance for memory consolidation is being explored.

Principle Investigator: Prof. Dr. Nikolai Axmacher
Start of the study: 2014
Status: Data acquisition completed, data analysis in progress

Study Coordination / Project Management

Prof. Dr. Nikolai Axmacher
nikolai.axmacher@rub.de
 +49 234 32-22674

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