Jochen René Thyrian
Interventional Health Care Research (IHCR)
Priv.-Doz. Dr. Jochen René Thyrian, Dipl.-Psych.
Group Leader
Ellernholzstr. 1-2
17489  Greifswald
 +49 3834 86-7592

Areas of investigation/research focus

The group was established on the 26th of November 2012 and, as result of a positive evaluation in a competitive tenure track program, is permanently funded since September 2019. Its research agenda is focused on the development and evaluation of interventions with population impact and their implementation into routine care.

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With such a focus it is complimentary to already existing research groups at the DZNE site Rostock/ Greifswald and at the DZNE site Witten. A close cooperation within these research groups is necessary and was established. Methods used in the research group are interventional studies, analyses and monitoring of implementation processes. IHCR has developed a distinct research agenda covering pressing issues in dementia care, which are:

  1. Timely diagnosis of dementia
  2. Optimizing treatment and care in primary care on the individual level
  3. Access, availability and quality of health care
  4. Vulnerable patient groups
  5. Caregiver burden and support

The five research lines focus on interventions tackling the most relevant targets in primary care. First of all procedures/ interventions need to be found to identify (vulnerable) patients. Then there need to be effective interventions those patients can benefit from. Moreover, interventions are needed that target caregivers as well. Last not least, the health care system providing effective interventions needs to be developed and analyzed to be most effective. We have found effective interventions, but for translation into routine care adaptions and implementation studies are needed.

Key Publications

Michalowsky B, Xie F, Eichler T, Hertel J, Kaczynski A, Kilimann I, Teipel S, Wucherer D, Zwingmann I, Thyrian JR, Hoffmann W. Cost-Effectiveness of a Collaborative Dementia Care Management – Results of a Cluster-Randomized Controlled Trial. Alzheimers Dement. 2019 Aug 01; 15:1296-1308. doi: 10.1016/j.jalz.2019.05.008
Nikelski A, Keller A, Schumacher-Schönert F, Dehl T, Laufer J, Sauerbrey U, Wucherer D, Dreier-Wolfgramm A, Michalowsky B, Zwingmann I, Vollmar HC, Hoffmann W, Kreisel SH, Thyrian JR. Supporting elderly people with cognitive impairment during and after hospital stays with Intersectoral Care Management [intersec-CM]: study protocol for a randomised controlled trial. Trials. 2019 Aug 30; 20:543. doi: 10.1186/s13063-019-3636-5
Jochen René Thyrian, Johannes Hertel, Diana Wucherer, Tilly Eichler, Bernhard Michalowsky, Adina Dreier-Wolfgramm, Ina Zwingmann, Ingo Kilimann, Stefan Teipel, Wolfgang Hoffmann. Effectiveness and safety of dementia care management in primary care: A randomized clinical trial. JAMA Psychiatry. 2017 Sep 30; 74:996-1004. doi: 10.1001/jamapsychiatry.2017.2124
Leonore Köhler, Claudia Meinke-Franze, Jürgen Hein, Konstanze Fendrich, Romy Heymann, Jochen René Thyrian, Wolfgang Hoffmann. Does an interdisciplinary network improve dementia care? Results from the IDemUck-Study. Current Alzheimer Research. 2013 Dec 31; 11:538-548. doi: 10.2174/1567205011666140618100727
Thyrian JR, John U. Population impact - definition, calculation and its use in prevention science in the example of tobacco smoking reduction. Health Policy. 2007 Nov 28; 82:348-56. doi: 10.1016/j.healthpol.2006.10.001


Thursdays 1:30-4:30 pm

Patients +49 800-7799001

(free of charge)

Professionals +49 180-779900

(9 Cent/Min. German landline, mobile and out of Germany possibly more expensive)

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