Neuroproteomics

Prof. Dr. Stefan Lichtenthaler

Featured publications

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The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130
Molecular neurodegeneration18(1),13()[10.1186/s13024-023-00596-6]DBCoverageBibTeX | EndNote: XML, Text | RIS

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Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity.
EMBO molecular medicine14(10),e16084()[10.15252/emmm.202216084]OpenAccess  Download fulltext FilesBibTeX | EndNote: XML, Text | RIS

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ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.
EMBO reports23(6),e54305()[10.15252/embr.202154305]OpenAccess  Download fulltext FilesBibTeX | EndNote: XML, Text | RIS

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The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.
Nature reviews / Neurology17(11),703 - 714()[10.1038/s41582-021-00545-1]BibTeX | EndNote: XML, Text | RIS

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An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
The EMBO journal39(20),e105693()[10.15252/embj.2020105693]pmc Download fulltextFulltext by Pubmed CentralBibTeX | EndNote: XML, Text | RIS

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Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3
The EMBO journal39(15),e103457()[10.15252/embj.2019103457] Download fulltextFulltextBibTeX | EndNote: XML, Text | RIS

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Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Nature reviews / Neuroscience22(10),1731-1742()[10.1038/s41593-019-0479-z]BibTeX | EndNote: XML, Text | RIS

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NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease.
EMBO molecular medicine11(4),e9695()[10.15252/emmm.201809695]OpenAccess Download fulltextFulltext by Pubmed CentralBibTeX | EndNote: XML, Text | RIS

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Pathology-linked protease caught in action.
Science / Science now363(6428),690-691()[10.1126/science.aaw5547]BibTeX | EndNote: XML, Text | RIS

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Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments.
The EMBO journal37(15),e99456()[10.15252/embj.201899456]pmc Download fulltextFulltext by Pubmed CentralBibTeX | EndNote: XML, Text | RIS

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Non-cell-autonomous function of DR6 in Schwann cell proliferation.
The EMBO journal37(7),e97390 ()[10.15252/embj.201797390]pmc Download fulltextFulltext by Pubmed CentralBibTeX | EndNote: XML, Text | RIS

Publications

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