Prof. Dr. Stefan Lichtenthaler

Group Leader

Feodor-Lynen-Str. 17
81377 München

stefan.lichtenthaler(at)dzne.de +49 89 4400-46425

Featured publications

Müller, S. A. (First author) ; Shmueli, M. D. ; Feng, X. ; Tüshaus, J. ; Schumacher, N. ; Clark, R. ; Smith, B. E. ; Chi, A. ; Rose-John, S. ; Kennedy, M. E. ; Lichtenthaler, S. F. (Last author)
The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130
Molecular neurodegeneration 18(1), 13 (2023) [10.1186/s13024-023-00596-6]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Güner, G. (First author) ; Assfalg, M. ; Zhao, K. ; Dreyer, T. ; Lahiri, S. ; Lo, Y. ; Slivinschi, B. ; Imhof, A. ; Jocher, G. ; Strohm, L. ; Behrends, C. ; Langosch, D. ; Bronger, H. ; Nimsky, C. ; Bartsch, J. W. ; Riddell, S. R. ; Steiner, H. ; Lichtenthaler, S. (Last author)
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity.
EMBO molecular medicine 14(10), e16084 (2022) [10.15252/emmm.202216084]2022 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Jocher, G. (First author) ; Grass, V. ; Tschirner, S. K. ; Riepler, L. ; Breimann, S. ; Kaya, T. ; Oelsner, M. ; Hamad, M. S. ; Hofmann, L. I. ; Blobel, C. P. ; Schmidt-Weber, C. B. ; Gokce, O. ; Jakwerth, C. A. ; Trimpert, J. ; Kimpel, J. ; Pichlmair, A. ; Lichtenthaler, S. (Last author)
ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.
EMBO reports 23(6), e54305 (2022) [10.15252/embr.202154305]2022 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

McDade, E. ; Voytyuk, I. ; Aisen, P. ; Bateman, R. J. ; Carrillo, M. C. ; De Strooper, B. ; Haass, C. ; Reiman, E. M. ; Sperling, R. ; Tariot, P. N. ; Yan, R. ; Masters, C. L. ; Vassar, R. ; Lichtenthaler, S. F. (Last author)
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.
Nature reviews / Neurology 17(11), 703 - 714 (2021) [10.1038/s41582-021-00545-1]2021 BibTeX | EndNote: XML, Text | RIS

Tüshaus, J. (First author) ; Müller, S. A. ; Kataka, E. S. ; Zaucha, J. ; Sebastian Monasor, L. ; Su, M. ; Güner, G. ; Jocher, G. ; Tahirovic, S. ; Frishman, D. ; Simons, M. ; Lichtenthaler, S. (Last author)
An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
The EMBO journal 39(20), e105693 (2020) [10.15252/embj.2020105693]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Pigoni, M. (First author) ; Hsia, H.-E. ; Hartmann, J. ; Njavro, J. ; Shmueli, M. ; Müller, S. A. ; Güner, G. ; Tüshaus, J. ; Kuhn, P.-H. ; Kumar, R. ; Gao, P. ; Tran, M. L. ; Ramazanov, B. ; Blank, B. ; Hipgrave Ederveen, A. L. ; Von Blume, J. ; Mulle, C. ; Gunnersen, J. M. ; Wuhrer, M. ; Rammes, G. ; Busche, M. A. ; Köglsperger, T. ; Lichtenthaler, S. (Last author)
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3
The EMBO journal 39(15), e103457 (2020) [10.15252/embj.2019103457]2020 Fulltext BibTeX | EndNote: XML, Text | RIS

Fecher, C. (First author) ; Trovò, L. ; Müller, S. ; Snaidero, N. ; Wettmarshausen, J. ; Heink, S. ; Ortiz, O. ; Wagner, I. ; Kühn, R. ; Hartmann, J. ; Karl, R. M. ; Konnerth, A. ; Korn, T. ; Wurst, W. ; Merkler, D. ; Lichtenthaler, S. F. ; Perocchi, F. ; Misgeld, T. (Last author)
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Nature reviews / Neuroscience 22(10), 1731-1742 (2019) [10.1038/s41593-019-0479-z]2019 BibTeX | EndNote: XML, Text | RIS

Brummer, T. (First author) ; Müller, S. A. ; Pan-Montojo, F. ; Yoshida, F. ; Fellgiebel, A. ; Tomita, T. ; Endres, K. ; Lichtenthaler, S. F. (Last author)
NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease.
EMBO molecular medicine 11(4), e9695 (2019) [10.15252/emmm.201809695]2019 OpenAccess Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Lichtenthaler, S. F. (First author) ; Güner, G. (Last author)
Pathology-linked protease caught in action.
Science / Science now 363(6428), 690-691 (2019) [10.1126/science.aaw5547]2019 BibTeX | EndNote: XML, Text | RIS

Lichtenthaler, S. (First author) ; Lemberg, M. K. ; Fluhrer, R.
Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments.
The EMBO journal 37(15), e99456 (2018) [10.15252/embj.201899456]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Colombo, A. (First author) ; Hsia, H.-E. ; Wang, M. ; Kuhn, P.-H. ; Brill, M. S. ; Canevazzi, P. ; Feederle, R. ; Taveggia, C. ; Misgeld, T. ; Lichtenthaler, S. F. (Last author)
Non-cell-autonomous function of DR6 in Schwann cell proliferation.
The EMBO journal 37(7), e97390 (2018) [10.15252/embj.201797390]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Publications

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