Mike O. Karl
Retina Regeneration and Degeneration
Prof. Dr. Mike O. Karl
Group Leader
Tatzberg 41
01307  Dresden

 +49 351 210 463-604


The complete list of publications is found here.

Sheik Pran Babu Sardar Pasha, Robert Münch, Patrick Schäfer, Peter Oertel, Alex M. Sykes, Yiqing Zhu, Mike O. Karl. Retinal cell death dependent reactive proliferative gliosis in the mouse retina. Scientific Reports. 2017 Nov 30; 7 doi: 10.1038/s41598-017-09743-8
Patrick Schäfer, Mike O. Karl. Prospective purification and characterization of Müller glia in the mouse retina regeneration assay. GLIA. 2017 Apr 30; 65:828-847. doi: 10.1002/glia.23130
Manuela Völkner, Marlen Zschätzsch, Maria Rostovskaya, Rupert W. Overall, Volker Busskamp, Konstantinos Anastassiadis, Mike O. Karl. Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis. Stem Cell Reports. 2016 Apr 11; 6:525-538. doi: 10.1016/j.stemcr.2016.03.001
Santos-Ferreira T, Völkner M, ...., *Karl MO & *Ader M (shared first & *corresponding authors). Differential integration of stem cell-derived photoreceptor transplants into mouse models of cone-rod dystrophy. Invest Ophthalmol Vis Sci. 2016 Jan 01; 57:3509-3520. doi: 10.1167/iovs.16-19087
Kati Löffler, Patrick Schäfer, Manuela Völkner, Tina Holdt, Mike O. Karl. Age-dependent Müller glia neurogenic competence in the mouse retina. GLIA. 2015 Sep 30; 63:1809-1824. doi: 10.1002/glia.22846
Zhu Y, Carido M, Meinhardt A, Kurth T, Karl MO, Ader M, Tanaka EM. Three-Dimensional Neuroepithelial Culture from Human Embryonic Stem Cells and Its Use for Quantitative Conversion to Retinal Pigment Epithelium. PlosONE. 2013 Jan 01; 8:e54552.
Nelson BR, Ueki Y, Reardon S, Georgi S, Karl MO, Hartman BH, Reh TA. Genome-wide analysis of Müller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate. PlosONE. 2011 Jan 01; 6:e22817.
Karl MO & Reh TA. Regenerative Medicine for Retinal Diseases: Activating the Endogenous Repair Mechanisms. Trends Mol Med. 2010 Jan 01; 16:193-202.
Karl MO, Hayes S, Nelson BR, Tan K, Buckingham B and Reh TA. Stimulation of neural regeneration in the mouse. Proc Natl Acad Sci U S A. 2008 Jan 01; 105:19508-13.
Lamba D., Karl M.O. and Reh TA. Neuronal Regeneration and Replacement: A view from the Eye. Cell Stem Cell. 2008 Jan 01; 2:538-549.
Karl, M.O., W. Kroeger, S. Wimmers, V. Milenkovic, M. Valtink, K. Engelmann, O. Strauss. Endogenous Gas6 and Ca2+-Channel Activation Modulate Phagocytosis by RPE. Cell Signal. 2008 Jan 01; 20:1159-1168.
Lamba D, Karl MO, Reh TA. Efficient Generation of Retinal Progenitor Cells from Human Embryonic Stem Cells. Proc Natl Acad Sci U S A. 2006 Jan 01; 103:12769-74.


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