Translational Brain Research
Prof. Dr. Jochen Herms
Group Leader
Feodor-Lynen-Str. 17
81377  München
 +49 89 4400-46427


The complete list of publications is found here.

Herms J, Dorostkar MM. Dendritic Spine Pathology in Neurodegenerative Diseases. Annu Rev Pathol. 2016 Jan 01; 11:221-50.
Chengyu Zou, Yuan Shi, Jasmin Ohli, Ulrich Schüller, Mario M. Dorostkar, Jochen Herms. Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease. Acta Neuropathologica. 2016 Jan 31; 131:235-246. doi: 10.1007/s00401-015-1527-8
Chengyu Zou, Sophie Crux, Stephane Marinesco, Elena Montagna, Carmelo Sgobio, Yuan Shi, Song Shi, Kaichuan Zhu, Mario M Dorostkar, Ulrike C Müller, Jochen Herms. Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis. EMBO Journal. 2016 Oct 16; 35:2213-2222. doi: 10.15252/embj.201694085
Chengyu Zou, Elena Montagna, Yuan Shi, Finn Peters, Lidia Blazquez-Llorca, Song Shi, Severin Filser, Mario M. Dorostkar, Jochen Herms. Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer’s disease. Acta Neuropathologica. 2015 Jun 25; 129:909-920. doi: 10.1007/s00401-015-1421-4
Filser S, Ovsepian SV,Masana M, Blazquez-Llorca L, Brandt Elvang A, Volbracht C, Müller MB, Jung CK, Herms J. Pharmacological Inhibition of BACE1 Impairs Synaptic Plasticity and Cognitive Functions. Biol Psychiatry. 2015 Jan 01; 77:729-39.
Ochs, Dorostkar, Aramuni, Schön, Filser, Pöschl, Kremer, Van Leuven, Ovsepian, Herms. Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin. Molecular Psychiatry. 2015 Apr 01; 20:482-489. doi: 10.1038/mp.2014.55
Johanna Neuner, Saak V. Ovsepian, Mario Dorostkar, Severin Filser, Aayush Gupta, Stylianos Michalakis, Martin Biel, Jochen Herms. Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb. Nature Communications. 2014 May 27; 5 doi: 10.1038/ncomms4915
Fuhrmann M, Bittner T, Jung CKE, Burgold S, Page RM, Mitteregger G, Haass C, LaFerla FM, Kretzschmar HA, Herms J. Microglia CX3CR1 knockout prevents neuron loss in an Alzheimer`s disease mouse model. Nature Neurosci. 2010 Jan 01; 13:411-413.
Finn Peters, Hazal Salihoglu, Eva Rodrigues, Etienne Herzog, Tanja Blume, Severin Filser, Mario Dorostkar, Derya R. Shimshek, Nils Brose, Ulf Neumann, Jochen Herms. BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology. Acta Neuropathologica. 2018 Apr 30; 135:695-710. doi: 10.1007/s00401-017-1804-9
Marinkovic P, Blumenstock S, Goltstein PM, Korzhova V, Peters F, Knebl A, Herms J. In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model. Brain. 2019 Apr 01; 142:1051-1062. doi: 10.1093/brain/awz035


Thursdays 1:30-4:30 pm

Patients +49 800-7799001

(free of charge)

Professionals +49 180-779900

(9 Cent/Min. German landline, mobile and out of Germany possibly more expensive)

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