The aim of our work is studying mechanisms of perinatal brain injury and establishing neuroprotective strategies. We use different methods as long-term neurofunctional outcome tests and cell-specific profiling.
The main focus is on:
- mechanisms of inflammation-sensitized experimental hypoxic-ischemic brain injury with and without hypothermia
- defining the role of microglia in our models of perinatal brain injury (hypoxia-ischemia, inflammation, prematurity)
- establishing early biomarkers of adverse outcome in our models
- establishing neuroprotective strategies