The aim of our work is studying mechanisms of perinatal brain injury and establishing neuroprotective strategies. We use different methods as long-term neurofunctional outcome tests and cell-specific profiling.

The main focus is on:

• mechanisms of inflammation-sensitized experimental hypoxic-ischemic brain injury with and without hypothermia
• defining the role of microglia in our models of perinatal brain injury (hypoxia-ischemia, inflammation, prematurity)
• establishing early biomarkers of adverse outcome in our models
• establishing neuroprotective strategies