Neural Circuit Computations

Prof. Dr. Jan Gründemann


The complete list of publications is found here.

Taylor JA, Hasegawa M, Benoit CM, Freire JA, Theodore M, Ganea DA, Lu T, Gründemann J. Single cell plasticity and population coding stability in auditory thalamus upon associative learning. bioRxiv. 2020 Apr 06; doi: 10.1101/2020.04.06.026401
Krabbe S, Paradiso E, d'Aquin S, Bitterman Y, Courtin J, Xu C, Yonehara K, Markovic M, Müller C, Eichlisberger T, Gründemann J, Ferraguti F, Lüthi A. Adaptive disinhibitory gating by VIP interneurons permits associative learning. Nat Neurosci. 2019 Nov 01; 22:1834-1843. doi: 10.1038/s41593-019-0508-y
Gründemann* J, Bitterman* Y, Lu T, Krabbe S, Grewe BF, Schnitzer MJ, Lüthi A. Amygdala ensembles encode behavioral states. Science. 2019 Apr 19; 364:eaav8736. doi: 10.1126/science.aav8736
Douglass AM, Kucukdereli H, Ponserre M, Markovic M, Gründemann J, Strobel C, Alcala Morales PL, Conzelmann KK, Lüthi A, Klein R. Central amygdala circuits modulate food consumption through a positive-valence mechanism. Nat Neurosci. 2017 Oct 01; 20:1384-1394. doi: 10.1038/nn.4623
Grewe BF, Gründemann J, Kitch LJ, Lecoq JA, Parker JG, Marshall JD, Larkin MC, Jercog PE, Grenier F, Li JZ, Lüthi A, Schnitzer MJ. Neural ensemble dynamics underlying a long-term associative memory. Nature. 2017 Mar 30; 543:670-675. doi: 10.1038/nature21682
Xu C, Krabbe S, Gründemann J, Botta P, Fadok JP, Osakada F, Saur D, Grewe BF, Schnitzer MJ, Callaway EM, Lüthi A. Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval. Cell. 2016 Nov 03; 167:961-972.e16. doi: 10.1016/j.cell.2016.09.051
Gründemann J, Lüthi A. Ensemble coding in amygdala circuits for associative learning. Curr Opin Neurobiol. 2015 Dec 01; 35:200-6. doi: 10.1016/j.conb.2015.10.005
Gründemann J, Clark BA. Calcium-Activated Potassium Channels at Nodes of Ranvier Secure Axonal Spike Propagation. Cell Rep. 2015 Sep 22; 12:1715-22. doi: 10.1016/j.celrep.2015.08.022
Wolff SBE*, Gründemann J*, Tovote P, Krabbe S, Jacobson GA, Müller C, Herry C, Ehrlich I, Friedrich RW, Letzkus JJ, Lüthi A (*co-first authors). Amygdala interneuron subtypes control fear learning through disinhibition. Nature. 2014 Jan 01; 509:453-458. doi: 10.1038/nature13258
Schlaudraff F, Gründemann J, Fauler M, Dragicevic E, Hardy J, Liss B. Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease. Neurobiol Aging. 2014 Oct 01; 35:2302-15. doi: 10.1016/j.neurobiolaging.2014.03.016
Gründemann J, Schlaudraff F, Haeckel O, Liss B. Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease. Nucleic Acids Res. 2008 Jan 01; 36:e38. doi: 10.1093/nar/gkn084.
Ramirez A, Heimbach A, Gründemann J, Stiller B, Hampshire D, Cid LP, Goebel I, Mubaidin AF, Wriekat AL, Roeper J, Al-Din A, Hillmer AM, Karsak M, Liss B, Woods CG, Behrens MI, Kubisch C. Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. Nat Genet. 0006 Oct 01; 38:1184-91. doi: 10.1038/ng1884

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