Tobias Boeckers
Translational Protein Biochemistry
Prof. Dr. Tobias M. Böckers
Group Leader
Albert Einstein Alle 11
89081  Ulm
 +49 731 500 232 20


The complete list of publications is found here.

Picchiarelli G, Demestre M, Zuko A, Been M, Higelin J, Dieterlé S, Goy MA, Mallik M, Sellier C, Scekic-Zahirovic J, Zhang L, Rosenbohm A, Sijlmans C, Aly A, Mersmann S, Sanjuan-Ruiz I, Hübers A, Messaddeq N, Wagner M, van Bakel N, Boutillier AL, Ludolph A, Lagier-Tourenne C, Boeckers TM, Dupuis L, Storkebaum E. FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis. Nat Neurosci. 2019 Oct 07; doi: 10.1038/s41593-019-0498-9
Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, Marroquin N, Nordin F, Hübers A, Weydt P, Pinto S, Press R, Millecamps S, Molko N, Bernard E, Desnuelle C, Soriani MH, Dorst J, Graf E, Nordström U, Feiler MS, Putz S, Boeckers TM, Meyer T, Winkler AS, Winkelman J, de Carvalho M, Thal DR, Otto M, Brännström T, Volk AE, Kursula P, Danzer KM, Lichtner P, Dikic I, Meitinger T, Ludolph AC, Strom TM, Andersen PM, Weishaupt JH.. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nature Neuroscience. 2015 May 01; 18:631-6. doi: 10.1038/nn.4000
Demestre M, Orth M, Foehr KJ, Achberger K, Ludolph AC, Liebau St, Boeckers TM. Formation and characterisation of neuromuscular junctions between hiPSc derived motoneurones and myotubes. Stem Cell Research. 2015 Sep 01; 15:328-336. doi: 10.1016/j.scr.2015.07.005
Schoen M, Reichel J, Demestre M, Putz St, Deshpande D, Proepper Ch, Liebau St, Schmeisser MJ, Ludolph AC, Michaelis J, Boeckers TM. Super-resolution microscopy reveals presynaptic localization of the ALS / FTD related protein FUS in hippocampal neurons. Front Cell Neurosci. 2016 Jan 12; 9:496. doi: 10.3389/fncel.2015.00496
Higelin J, Demestre M, Putz St, Lutz AK, Bausinger J, Hübers AK, Klingenstein M, Barbi G, Liebau St, Speit G, Hermann A, Ludolph AC, Boeckers TM. FUS mislocalisation and vulnerability to DNA damage in ALS patients derived hiPSCs and aging motoneurons. Front Cell Neuroscience. 2016 Dec 26; 10:290. doi: 10.3389/fncel.2016.00290
Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt J, Holzmann KH, Troost D, Ludolph A, Boeckers TM, Liebau St, Petri S, Cordes N, Hyman A, Wegner F, Stephan G, Weis J, Storch A, and Hermann A. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and aggregation formation. Nature Communication. 2018 Jan 23; 9:335. doi: 10.1038/s41467-017-02299-1


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