… diseases in the DZNE. Included are probands with e.g. Alzheimer's disease, frontotemporal dementia, Parkinson's disease, amyotrophic lateral sclerosis, ataxia and amyloid angiopathy.
The time interval of…
… morphometry, volumetry, phenotyping and lesion detection Parametric evaluation (e.g., iron load in Parkinson’s disease model, neuroinflammation) Diffusion weighted Imaging and fiber tractography for white…
… Further, speech may also be affected, becoming indistinct and slurred.
Ataxias differ from Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) in that ataxias are mostly disturbances in…
… to the brain and nervous system, such as Alzheimer's disease (AD), Frontotemporal dementia (FTD) and Parkinson's disease (PD).
We are also interested in exploring a role of non-coding part of the genome.…
… Diseases (DZNE)
The DZNE investigates all aspects of neurodegenerative diseases (such as Alzheimer’s, Parkinson’s and Amyotrophic lateral sclerosis) in order to develop novel approaches of prevention, treatment,…
… As of today, 1.8 million Germans, mostly elderly, are affected by dementia and about 250,000 by Parkinson's disease. Unfortunately, since effective therapies to slow or reverse the progression of either…
… synaptic dysfunction in neurodegenerative diseases like Alzheimer’s disease, frontotemporal Dementia and Parkinson’s disease. Synaptic failure is believed to be one of the initial events in Alzheimer`s disease and…
… pathogenicity in neurodegenerative disorders including frontotemporal lobar degeneration (FTLD) and Parkinson’s disease (PD).
In this context we have pursued genetic studies toward finding of genes…
…ine. We want to pave the way for such precisely tailored medical interventions for diseases like Alzheimer’s, Parkinson’s or ALS.”
The new research area will also benefit from the DZNE’s experience in artificial…
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