Identification of common variants associated with human hippocampal and intracranial volumes.

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann O, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; the Alzheimer's Disease Neuroimaging Initiative (ADNI); EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group (SYS), Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, Decarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM. Nat Genet. 2012 Apr 15;44(5):552-561. doi: 10.1038/ng.2250.


open PubMed Abstract

Cognitive impairment in primary ambulatory health care: pharmacotherapy and the use of potentially inappropriate medicine.

Fiss T, Thyrian JR, Fendrich K, van den Berg N, Hoffmann W. Int J Geriatr Psychiatry. 2012 Apr 16. doi: 10.1002/gps.3806. [Epub ahead of print]


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Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success.

Balbach ST, Esteves TC, Houghton FD, Siatkowski M, Pfeiffer MJ, Tsurumi C, Kanzler B, Fuellen G, Boiani M. PLoS One. 2012;7(4):e35322. Epub 2012 Apr 18.


open PubMed Abstract

Life years gained. Long-term trends in mortality by causes of death in Germany and in an international perspective.[Gewonnene Lebensjahre: Langfristige Trends der Sterblichkeit nach Todesursachen in Deutschland und im Internationalen Vergleich.]

Doblhammer G, Kreft D, Dethloff A. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Apr;55(4):448-58.


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Medication review for dementia patients.[Medikationsreview in der psychiatrischen institutsambulanz.]

Jahns KP, Kilimann I, Ritter CA, Hoffmann W, Teipel SJ, Fiss T. Med Monatsschr Pharm. 2012 Mar;35(3):95-103.


open PubMed Abstract

Isolated motor neglect following infarction of the posterior limb of the right internal capsule: a case study with diffusion tensor imaging-based tractography.

Y Likitjaroen, NC Suwanwela, AJ Mitchell, S Lerdlum, K Phanthumchinda, SJ Teipel; J Neurol. 2012 Jan;259(1):100-5. Epub 2011 Jun 22.


open PubMed Abstract

Anatomical MRI and DTI in the Diagnosis of Alzheimer's Disease: A European Multicenter Study.

Teipel SJ, Wegrzyn M, Meindl T, Frisoni G, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Ewers M. J Alzheimers Dis. 2012 Jan 1;31(0):S33-47.


open PubMed Abstract

Multicenter stability of diffusion tensor imaging measures: A European clinical and physical phantom study.

SJ Teipel, S Reuter, B Stieltjes, J Acosta-Cabronero, U Ernemann, A Fellgiebel, M Filippi, G Frisoni, F Hentschel, F Jessen, S Klöppel, T Meindl, PJ Pouwels, KH Hauenstein, H Hampel; Psychiatry Res. 2011 Dec 30;194(3):363-71. Epub 2011 Nov 9.


open PubMed Abstract

The future of Alzheimer's disease: the next 10 years.

H Hampel, D Prvulovic, S Teipel, F Jessen, C Luckhaus, L Frölich, MW Riepe, R Dodel, T Leyhe, L Bertram, W Hoffmann, F Faltraco; German Task Force on Alzheimer's Disease (GTF-AD); Prog Neurobiol. 2011 Dec;95(4):718-28. Epub 2011 Nov 22.


open PubMed Abstract

Detection of Alzheimer's Disease with Diffusion Tensor Imaging and Deformation-Based Morphometry.

Friese U, Meindl T, Herpertz SC, Reiser MF, Hampel H, Teipel SJ. Advances in Alzheimer's Disease Volume 02, 2011 Handbook of Imaging the Alzheimer Brain. DOI: 10.3233/978-1-60750-793-2-473.


open Abstract

A genome-wide association study of aging

S Walter, G Atzmon, EW Demerath, ME Garcia, RC Kaplan, M Kumari, KL Lunetta, Y Milaneschi, T Tanaka, GJ Tranah, U Völker, L Yu, A Arnold, EJ Benjamin, R Biffar, AS Buchman, E Boerwinkle, D Couper, PL De Jager, DA Evans, TB Harris, W Hoffmann, A Hofman, D Karasik, DP Kiel, T Kocher, M Kuningas, LJ Launer, KK Lohman, PL Lutsey, J Mackenbach, K Marciante, BM Psaty, EM Reiman, JI Rotter, S Seshadri, MD Shardell, AV Smith, C van Duijn, J Walston, MC Zillikens, S Bandinelli, SE Baumeister, DA Bennett, L Ferrucci, V Gudnason, M Kivimaki, Y Liu, JM Murabito, AB Newman, H Tiemeier, N Franceschini; Neurobiol Aging. 2011 Nov;32(11):2109.e15-28. Epub 2011 Jul 22.


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Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

M Krohn, C Lange, J Hofrichter, K Scheffler, J Stenzel, J Steffen, T Schumacher, T Brüning, A-S Plath, F Alfen, A Schmidt, F Winter, K Rateitschak, A Wree, J Gsponer, LC Walker, J Pahnke; J Clin Invest. 2011 Oct 3;121(10):3924-31. doi: 10.1172/JCI57867. Epub 2011 Sep 1.


open PubMed Abstract

Incidence of restless legs syndrome in two population-based cohort studies in Germany.

A Szentkiralyi, K Fendrich, W Hoffmann, S Happe, K Berger; Sleep Med. 2011 Oct;12(9):815-20.


open PubMed Abstract

Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: Effect of different processing and analysis approaches on sample sizes.

Teipel SJ, Peters O, Heuser I, Jessen F, Maier W, Froelich L, Arlt S, Hüll M, Gertz HJ, Kornhuber J, Wiltfang J, Thome J, Rienhoff O, Meindl T, Hampel H, Grothe M. World J Biol Psychiatry. 2011 Sep;12 Suppl 1:109-13. doi: 10.3109/15622975.2011.603222.


open PubMed Abstract

Frequency and determinants of potential drug-drug interactions in an elderly population receiving regular home visits by GPs - results of the home medication review in the AGnES-studies

W Hoffmann, N Van Den Berg, JR Thyrian, T Fiss; Pharmacoepidemiol Drug Saf. 2011 Sep 15. doi: 10.1002/pds.2224. [Epub ahead of print]


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Live longer, suffer more? Trends in life expectancy and health

G Doblhammer, D Kreft; Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Aug;54(8):907-14.


open PubMed Abstract

Antihypertensive therapy is associated with reduced rate of conversion to Alzheimer's disease in midregional proatrial natriuretic Peptide stratified subjects with mild cognitive impairment.

P Schneider, K Buerger, S Teipel, O Uspenskaya, O Hartmann, O Hansson, L Minthon, D Rujescu, HJ Moeller, H Zetterberg, K Blennow, A Ernst, A Bergmann, H Hampel; Biol Psychiatry. 2011 Jul 15;70(2):145-51. Epub 2011 Mar 31.


open PubMed Abstract

Staging Alzheimer’s disease progression with multimodality neuroimaging.

M Ewers, GB Frisoni, SJ Teipel, LT Grinberg, E Jr. Amaro, H Heinsen, PM Thompson, H Hampel, Prog. Neurobiol, 2011 June 22, Epub ahead of print.


open PubMed Abstract

Proteomic analysis of mouse oocytes reveals 28 candidate factors of the "reprogrammome".

MJ Pfeiffer, M Siatkowski, Y Paudel, ST Balbach, N Baeumer, N Crosetto, HC Drexler, G Fuellen, M Boiani; J Proteome Res. 2011 May 6;10(5):2140-53. Epub 2011 Mar 29.


open PubMed Abstract

Zeitbedarf und Kosten für die Umsetzung eines Medikamentenreviews und assoziierter pharmazeutischer und medizinischer Evaluation im ambulanten Versorgungssektor.

T Fiß, M Schaefer, N van den Berg, W Hoffmann; Gesundheitswesen. 2011 May 11. [Epub ahead of print]


open PubMed Abstract

Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression.

SJ Teipel, R Buchert, J Thome, H Hampel, J Pahnke; Prog Neurobiol. 2011 May 12. [Epub ahead of print]


open PubMed Abstract

Left Anterior Temporal Lobe Sustains Naming in Alzheimer's Dementia and Mild Cognitive Impairment.

L Frings, S Klöppel, S Teipel, O Peters, L Frölich, J Pantel, J Schröder, HJ Gertz, S Arlt, I Heuser, J Kornhuber, J Wiltfang, W Maier, F Jessen, H Hampel, M Hüll; Curr Alzheimer Res. 2011 May 18. [Epub ahead of print]


open PubMed Abstract

Long-Term Stability of Alzheimer's Disease Biomarker Proteins in Cerebrospinal Fluid.

CG Schipke, F Jessen, S Teipel, C Luckhaus, J Wiltfang, H Esselmann, L Frölich, W Maier, E Rüther, FL Heppner, S Prokop, I Heuser, O Peters; J Alzheimers Dis. 2011 May 23. [Epub ahead of print]


open PubMed Abstract

Evaluation of systemic targeting of RET oncogene-based MTC with tumor-selective peptide-tagged Ad vectors in clinical mouse models.

A Schmidt, C Eipel, K Fürst, N Sommer, J Pahnke, BM Pützer; Gene Ther. 2011 Apr;18(4):418-23. Epub 2011 Jan 13.


open PubMed Abstract

Effects of a Newly Developed Cognitive Intervention in Amnestic Mild Cognitive Impairment and mild Alzheimer's disease: A Pilot Study.

VC Buschert, U Friese, SJ Teipel, P Schneider, W Merensky, D Rujescu, HJ Möller, H Hampel, K Buerger; J Alzheimers Dis. 2011 Apr 11. [Epub ahead of print]


open PubMed Abstract