Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space

Bajaj R, Jaremko Ł, Jaremko M, Becker S, Zweckstetter M.

Structure. 2014 Oct 7;22(10):1501-11. doi: 10.1016/j.str.2014.07.015. Epub 2014 Sep 25.

 


open Pubmed Abstract

Ascertainment bias causes false signal of anticipation in genetic prion disease

Minikel EV, Zerr I, Collins SJ, Ponto C, Boyd A, Klug G, Karch A, Kenny J, Collinge J, Takada LT, Forner S, Fong JC, Mead S, Geschwind MD.

Am J Hum Genet. 2014 Oct 2;95(4):371-82. doi: 10.1016/j.ajhg.2014.09.003.

 


open Pubmed Abstract

CR1 is potentially associated with rate of decline in sporadic Alzheimer's disease

Schmidt C, Wolff M, von Ahsen N, Lange K, Friede T, Zerr I.

J Clin Neurosci. 2014 Oct;21(10):1705-8. doi: 10.1016/j.jocn.2014.03.015. Epub 2014 Jul 4.

 


open Pubmed Abstract

First symptom and initial diagnosis in sporadic CJD patients in Germany

Krasnianski A, Kaune J, Jung K, Kretzschmar HA, Zerr I.

J Neurol. 2014 Sep;261(9):1811-7. doi: 10.1007/s00415-014-7410-z. Epub 2014 Jul 15.

 


open Pubmed Abstract

Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases

Feneberg E, Steinacker P, Lehnert S, Schneider A, Walther P, Thal DR, Linsenmeier M, Ludolph AC, Otto M.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep;15(5-6):351-6. doi: 10.3109/21678421.2014.905606. Epub 2014 May 16.

 


open Pubmed Abstract

Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease

Llorens F, Zafar S, Ansoleaga B, Shafiq M, Blanco R, Carmona M, Grau-Rivera O, Nos C, Gelpí E, Del Río JA, Zerr I, Ferrer I.

Neuropathol Appl Neurobiol. 2014 Aug 18. doi: 10.1111/nan.12175. [Epub ahead of print]

PMID: 25134744


open Pubmed Abstract

Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease

Llorens F, López-González I, Thüne K, Carmona M, Zafar S, Andréoletti O, Zerr I, Ferrer I.

Front Aging Neurosci. 2014 Aug 4;6:198. doi: 10.3389/fnagi.2014.00198. eCollection 2014.

 


open Pubmed Abstract

Toward the functional oligomerization state of tryptophan-rich sensory proteins

Jaremko L, Jaremko M, Becker S, Zweckstetter M.

Protein Sci. 2014 Aug;23(8):1154-60. doi: 10.1002/pro.2487. Epub 2014 May 22.

 


open Pubmed Abstract

MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease

Banzhaf-Strathmann J, Benito E, May S, Arzberger T, Tahirovic S, Kretzschmar H, Fischer A, Edbauer D.

EMBO J. 2014 Aug 1;33(15):1667-80. doi: 10.15252/embj.201387576. Epub 2014 Jul 7.

 


open Pubmed Abstract

Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy

Jensen MR, Zweckstetter M, Huang JR, Blackledge M.

Chem Rev. 2014 Jul 9;114(13):6632-60. doi: 10.1021/cr400688u. Epub 2014 Apr 11. No abstract available


open Pubmed Abstract

CR1 is potentially associated with rate of decline in sporadic Alzheimer's disease

Schmidt C, Wolff M, von Ahsen N, Lange K, Friede T, Zerr I.

J Clin Neurosci. 2014 Oct;21(10):1705-8. doi: 10.1016/j.jocn.2014.03.015. Epub 2014 Jul 4.

 


open Pubmed Abstract

α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner

Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, Szegő ÉM, Guerreiro P, Lázaro DF, Braus GH, Fernandez CO, Griesinger C, Becker S, Goody RS, Itzen A, Giorgini F, Outeiro TF, Zweckstetter M.

Neurobiol Dis. 2014 Oct;70:149-61. doi: 10.1016/j.nbd.2014.06.018. Epub 2014 Jun 28.

 


open Pubmed Abstract

Histone-acetylation: A link between Alzheimer's disease and post-traumatic stress disorder?

Bahari-Javan S, Sananbenesi F, Fischer A.

Front Neurosci. 2014 Jun 24;8:160. doi: 10.3389/fnins.2014.00160. eCollection 2014. Review.

 


open Pubmed Abstract

The neuronal activity-driven transcriptome

Benito E, Barco A.

Mol Neurobiol. 2015;51(3):1071-88. doi: 10.1007/s12035-014-8772-z. Epub 2014 Jun 17


open Pubmed abstract

K-lysine acetyltransferase 2a regulates a hippocampal gene-expression network linked to memory formation.

Stilling, R.M., Rönicke, R. , Benito, E., Urbanke, H. Capece, V., Burkhardt, S. Bahari-Javan, S., Barth, J., Sananbenesi, F., Schütz, A.L., Dyczkowski, J., Martinez-hernandez, a., kerimoglu, c., dent, S.Y.R., Bonn, S., Reymann, K.G., Fischer. A. EMBO J. In press


MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease.

Banzhaf-Strathmann, J., Benito, E. May, S. Arzberger, T., Tahirovic, S., Kretzschmar, H. Fischer, A., Edbauer, D. EMBO J., in press


Histone-acetylation: A link between Alzheimer’s disease and post-traumatic stress disorder?

Bahari-Javan, S., Sananbenesi, F., Fischer, A. Frontiers in Neuroscience, in press


open Abstract

Detection of a transient intramolecular hydrogen bond using 1JNH scalar couplings

Xiang S, Zweckstetter M. J Magn Reson. 2014 Jun;243:93-7. doi: 10.1016/j.jmr.2014.04.004. Epub 2014 Apr 18.


open PubMed Abstract

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

Cramm M1, Schmitz M, Karch A, Zafar S, Varges D, Mitrova E, Schroeder B, Raeber A, Kuhn F, Zerr I. Mol Neurobiol. 2014 May 9. [Epub ahead of print]


open PubMed Abstract

Nucleotide interactions of the human voltage-dependent anion channel

Villinger S, Giller K, Bayrhuber M, Lange A, Griesinger C, Becker S, Zweckstetter M. J Biol Chem. 2014 May 9;289(19):13397-406. doi: 10.1074/jbc.M113.524173. Epub 2014 Mar 25.


open PubMed Abstract

Site-specific copper-catalyzed oxidation of α-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson's disease

Miotto MC, Rodriguez EE, Valiente-Gabioud AA, Torres-Monserrat V, Binolfi A, Quintanar L, Zweckstetter M, Griesinger C, Fernández CO. Inorg Chem. 2014 May 5;53(9):4350-8. doi: 10.1021/ic4031377. Epub 2014 Apr 11.


open PubMed Abstract

Targeting histone-modifications in Alzheimer's disease. What is the evidence that this is a promising therapeutic avenue?

Fischer A.

Neuropharmacology. 2014 May;80C:95-102. doi: 10.1016/j.neuropharm.2014.01.038. Epub 2014 Jan 31. Review.

 


open Pubmed Abstract

Epigenetic memory: the Lamarckian brain.

Fischer A. EMBO J. 2014 May 2;33(9):945-67. doi: 10.1002/embj.201387637. Epub 2014 Apr 9.


open PubMed Abstract

Turn plasticity distinguishes different modes of amyloid-β aggregation

Rezaei-Ghaleh N, Amininasab M, Giller K, Kumar S, Stündl A, Schneider A, Becker S, Walter J, Zweckstetter M. J Am Chem Soc. 2014 Apr 2;136(13):4913-9. doi: 10.1021/ja411707y. Epub 2014 Mar 21.


open PubMed Abstract

Characterization of the effects of phosphorylation by CK2 on the structure and binding properties of human HP1β

Munari F, Gajda MJ, Hiragami-Hamada K, Fischle W, Zweckstetter M. FEBS Lett. 2014 Apr 2;588(7):1094-9. doi: 10.1016/j.febslet.2014.02.019. Epub 2014 Feb 20.


open PubMed Abstract