Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage

Zafar S, Schmitz M, Younus N, Tahir W, Shafiq M, Llorens F, Ferrer I, Andéoletti O, Zerr I.

J Mol Neurosci. 2015 Jun;56(2):329-48. doi: 10.1007/s12031-015-0544-3. Epub 2015 Apr 21.

PMID: 25896910


open Pubmed Abstract

Lost in translocation: The functions of the 18-kD translocator protein

Gut P, Zweckstetter M, Banati RB.

Trends Endocrinol Metab. 2015 May 28. pii: S1043-2760(15)00080-6. doi: 10.1016/j.tem.2015.04.001. [Epub ahead of print] Review.

PMID: 26026242


open Pubmed Abstract

Copper Binding to the N-Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding

Miotto MC, Valiente-Gabioud AA, Rossetti G, Zweckstetter M, Carloni P, Selenko P, Griesinger C, Binolfi A, Fernández CO.

J Am Chem Soc. 2015 May 27;137(20):6444-7. doi: 10.1021/jacs.5b01911. Epub 2015 May 15.

PMID: 25939020


open Pubmed Abstract

Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions

Ramljak S, Schmitz M, Zafar S, Wrede A, Schenkel S, Asif AR, Carimalo J, Doeppner TR, Schulz-Schaeffer WJ, Weise J, Zerr I.

Exp Neurol. 2015 Sep;271:155-67. doi: 10.1016/j.expneurol.2015.04.025. Epub 2015 May 27.


open Pubmed Abstract

Structural Integrity of the A147T Polymorph of Mammalian TSPO

Jaremko M, Jaremko Ł, Giller K, Becker S, Zweckstetter M.

Chembiochem. 2015 May 12. doi: 10.1002/cbic.201500217. [Epub ahead of print]

PMID: 25974690


open Pubmed Abstract

Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic

Schmitz M, Ebert E, Stoeck K, Karch A, Collins S, Calero M, Sklaviadis T, Laplanche JL, Golanska E, Baldeiras I, Satoh K, Sanchez-Valle R, Ladogana A, Skinningsrud A, Hammarin AL, Mitrova E, Llorens F, Kim YS, Green A, Zerr I.

Mol Neurobiol. 2015 May 7. [Epub ahead of print]

PMID: 25947081


open Pubmed Abstract

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH, Schneider A.

Acta Neuropathol. 2015 May


open Pubmed abstract

A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk

Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, Hofman A, Haïk S, Combarros O, Berciano J, Uitterlinden AG, Collins SJ, Budka H, Brandel JP, Laplanche JL, Pocchiari M, Zerr I, Knight RS, Will RG, van Duijn CM.

PLoS One. 2015 Apr 28;10(4):e0123654. doi: 10.1371/journal.pone.0123654. eCollection 2014.

PMID: 25918841


open Pubmed Abstract

Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage

Zafar S, Schmitz M, Younus N, Tahir W, Shafiq M, Llorens F, Ferrer I, Andéoletti O, Zerr I.

J Mol Neurosci. 2015 Apr 21. [Epub ahead of print]

PMID: 25896910


open Pubmed Abstract

Super-Resolution Microscopy of Cerebrospinal Fluid Biomarkers as a Tool for Alzheimer's Disease Diagnostics

Zhang WI, Antonios G, Rabano A, Bayer TA, Schneider A, Rizzoli SO.

J Alzheimers Dis. 2015 Apr 16. [Epub ahead of print]

PMID: 25881910


open Pubmed Abstract

HYCUD: A computational tool for prediction of effective rotational correlation time in flexible proteins

Rezaei-Ghaleh N, Klama F, Munari F, Zweckstetter M.

Bioinformatics. 2015 Apr 15;31(8):1319-21. doi: 10.1093/bioinformatics/btu824. Epub 2014 Dec 12.

PMID: 25505088


open Pubmed Abstract

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH, Schneider A.

Acta Neuropathol. 2015 Mar 17. [Epub ahead of print]

PMID: 25778619


open Pubmed Abstract

N6-Adenosine Methylation in MiRNAs

Berulava T, Rahmann S, Rademacher K, Klein-Hitpass L, Horsthemke B.

PLoS One. 2015 Feb 27;10(2):e0118438. doi: 10.1371/journal.pone.0118438. eCollection 2015.

PMID: 25723394 [PubMed - in process]


open Pubmed Abstract

Cerebrospinal fluid tau levels are a marker for molecular subtype in sporadic Creutzfeldt-Jakob disease

Karch A, Hermann P, Ponto C, Schmitz M, Arora A, Zafar S, Llorens F, Müller-Heine A, Zerr I.

Neurobiol Aging. 2015 Feb 7. pii: S0197-4580(15)00070-6. doi: 10.1016/j.neurobiolaging.2015.01.021. [Epub ahead of print]

PMID: 25749129


open Pubmed Abstract

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type

Popp J, Wolfsgruber S, Heuser I, Peters O, Hüll M, Schröder J, Möller HJ, Lewczuk P, Schneider A, Jahn H, Luckhaus C, Perneczky R, Frölich L, Wagner M, Maier W, Wiltfang J, Kornhuber J, Jessen F.

Neurobiol Aging. 2015 Feb;36(2):601-7. doi: 10.1016/j.neurobiolaging.2014.10.031. Epub 2014 Oct 31.

 


open Pubmed Abstract

Rare structural genetic variation in human prion diseases

Lukic A, Uphill J, Brown CA, Beck J, Poulter M, Campbell T, Adamson G, Hummerich H, Whitfield J, Ponto C, Zerr I, Lloyd SE, Collinge J, Mead S.

Neurobiol Aging. 2015 Jan 22. pii: S0197-4580(15)00044-5.


open Pubmed Abstract

Multiple paramagnetic effects through a tagged reporter protein

Camacho-Zarco AR, Munari F, Wegstroth M, Liu WM, Ubbink M, Becker S, Zweckstetter M.

Angew Chem Int Ed Engl. 2015 Jan 2;54(1):336-9. doi: 10.1002/anie.201408615. Epub 2014 Oct 7.

 


open Pubmed Abstract

Characterization of the MeCP2R168X knockin mouse model for Rett syndrome

Guadalupe T, Zwiers MP, Wittfeld K, Teumer A, Vasquez AA, Hoogman M, Hagoort P, Fernandez G, Buitelaar J, van Bokhoven H, Hegenscheid K, Völzke H, Franke B, Fisher SE, Grabe HJ, Francks C.

Cortex. 2015 Jan;62:41-55. doi: 10.1016/j.cortex.2014.07.015. Epub 2014 Aug 7.

 


open Pubmed Abstract

Interaction of the intermembrane space domain of Tim23 protein with mitochondrial membranes

Bajaj R, Munari F, Becker S, Zweckstetter M.

J Biol Chem. 2014 Dec 12;289(50):34620-6. doi: 10.1074/jbc.M114.595702. Epub 2014 Oct 27.

 


open Pubmed Abstract

A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins

Yao X, Becker S, Zweckstetter M.

J Biomol NMR. 2014 Dec;60(4):231-40. doi: 10.1007/s10858-014-9872-9. Epub 2014 Nov 4.

 


open Pubmed Abstract

Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions

Miotto MC, Binolfi A, Zweckstetter M, Griesinger C, Fernández CO.

J Inorg Biochem. 2014 Dec;141:208-11. doi: 10.1016/j.jinorgbio.2014.08.012. Epub 2014 Sep 3.

 


open Pubmed Abstract

A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins

Yao X, Becker S, Zweckstetter M.

J Biomol NMR. 2014 Dec;60(4):231-40. doi: 10.1007/s10858-014-9872-9. Epub 2014 Nov 4.

 


open Pubmed Abstract

Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2

Gattin Z, Schneider R, Laukat Y, Giller K, Maier E, Zweckstetter M, Griesinger C, Benz R, Becker S, Lange A.

J Biomol NMR. 2015 Apr;61(3-4):311-20. doi: 10.1007/s10858-014-9876-5. Epub 2014 Nov 16.

 


open Pubmed Abstract

De-regulation of gene expression and alternative splicing affects distinct cellular pathways in the aging hippocampus

Stilling RM, Benito E, Gertig M, Barth J, Capece V, Burkhardt S, Bonn S, Fischer A.

Front Cell Neurosci. 2014 Nov 13;8:373. doi: 10.3389/fncel.2014.00373. eCollection 2014.

PMID: 25431548


open Pubmed Abstract

Long-range correlated dynamics in intrinsically disordered proteins

Parigi G, Rezaei-Ghaleh N, Giachetti A, Becker S, Fernandez C, Blackledge M, Griesinger C, Zweckstetter M, Luchinat C.

J Am Chem Soc. 2014 Nov 4. [Epub ahead of print]

 


open Pubmed Abstract