Coexpressed Auxiliary Subunits Exhibit Distinct Modulatory Profiles on AMPA Receptor Function

Khodosevich K, Jacobi E, Farrow P, Schulmann A, Rusu A, Zhang L, Sprengel R, Monyer H, von Engelhardt J.

Neuron. 2014 Aug 6;83(3):601-15. doi: 10.1016/j.neuron.2014.07.004. Epub 2014 Jul 24.

 


open Pubmed Abstract

Peptidoglycan recognition protein genes and risk of Parkinson's disease

Goldman SM, Kamel F, Ross GW, Jewell SA, Marras C, Hoppin JA, Umbach DM, Bhudhikanok GS, Meng C, Korell M, Comyns K, Hauser RA, Jankovic J, Factor SA, Bressman S, Lyons KE, Sandler DP, Langston JW, Tanner CM.

Mov Disord. 2014 Aug;29(9):1171-80. doi: 10.1002/mds.25895. Epub 2014 May 17.

 


open Pubmed Abstract

Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study

McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM.

J Am Acad Child Adolesc Psychiatry. 2014 Aug;53(8):910-9. doi: 10.1016/j.jaac.2014.04.022. Epub 2014 Jun 24.

 


open Pubmed Abstract

Transport and diffusion of Tau protein in neurons

Scholz T, Mandelkow E.

Cell Mol Life Sci. 2014 Aug;71(16):3139-50. doi: 10.1007/s00018-014-1610-7. Epub 2014 Apr 1. Review.

 


open Pubmed Abstract

Neural communication patterns underlying conflict detection, resolution, and adaptation

Oehrn CR, Hanslmayr S, Fell J, Deuker L, Kremers NA, Do Lam AT, Elger CE, Axmacher N.

J Neurosci. 2014 Jul 30;34(31):10438-52. doi: 10.1523/JNEUROSCI.3099-13.2014.

 


open Pubmed Abstract

Stages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicity

Kumar S, Tepper K, Kaniyappan S, Biernat J, Wegmann S, Mandelkow EM, Müller DJ, Mandelkow E.

J Biol Chem. 2014 Jul 18;289(29):20318-32. doi: 10.1074/jbc.M114.554725. Epub 2014 May 13.

 


open Pubmed Abstract

Microtubule self-organization via protein-RNA network crosstalk

Coles CH, Bradke F.

Cell. 2014 Jul 17;158(2):245-7. doi: 10.1016/j.cell.2014.06.044.

 


open Pubmed Abstract

Function of inhibitory micronetworks is spared by Na+ channel-acting anticonvulsant drugs

Pothmann L, Müller C, Averkin RG, Bellistri E, Miklitz C, Uebachs M, Remy S, Menendez de la Prida L, Beck H.

J Neurosci. 2014 Jul 16;34(29):9720-35. doi: 10.1523/JNEUROSCI.2395-13.2014.

 


open Pubmed Abstract

Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment

Hettich MM, Matthes F, Ryan DP, Griesche N, Schröder S, Dorn S, Krauβ S, Ehninger D.

PLoS One. 2014 Jul 15;9(7):e102420. doi: 10.1371/journal.pone.0102420. eCollection 2014.

 


open Pubmed Abstract

The anti-diabetic drug metformin reduces BACE1 protein level by interfering with the MID1 complex

Hettich MM, Matthes F, Ryan DP, Griesche N, Schröder S, Dorn S, Krauβ S, Ehninger D.

PLos One. 2014 Jul 15;9(7):e102420. doi: 10.1371/journal.pone.0102420. eCollection 2014.

 


open Pubmed Abstract

Direct action of endocrine disrupting chemicals on human sperm

Schiffer C, Müller A, Egeberg DL, Alvarez L, Brenker C, Rehfeld A, Frederiksen H, Wäschle B, Kaupp UB, Balbach M, Wachten D, Skakkebaek NE, Almstrup K, Strünker T.

EMBO Rep. 2014 Jul;15(7):758-65. doi: 10.15252/embr.201438869. Epub 2014 May 12.

 


open Pubmed Abstract

Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment

Wolfsgruber S, Wagner M, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Pantel J, Rienhoff O, Rüther E, Henn F, Wiltfang J, Maier W, Kornhuber J, Jessen F.

PLoS One. 2014 Jul 14;9(7):e100812. doi: 10.1371/journal.pone.0100812. eCollection 2014.

 


open Pubmed Abstract

Current approaches and future role of high content imaging in safety sciences and drug discovery

van Vliet E, Daneshian M, Beilmann M, Davies A, Fava E, Fleck R, Julé Y, Kansy M, Kustermann S, Macko P, Mundy WR, Roth A, Shah I, Uteng M, van de Water B, Hartung T, Leist M.

ALTEX. 2014;31(4):479-93. doi: dx.doi.org/10.14573/altex.1405271. Epub 2014 Jul 14.

 


open Pubmed Abstract

Longevity, aging and rapamycin

Ehninger D, Neff F, Xie K.

Cell Mol Life Sci. 2014 Jul 12. [Epub ahead of print]

 


open Pubmed Abstract

An investigation of facial emotion recognition impairments in alexithymia and its neural correlates

Jongen S, Axmacher N, Kremers NA, Hoffmann H, Limbrecht-Ecklundt K, Traue HC, Kessler H.

Behav Brain Res. 2014 Sep 1;271:129-39. doi: 10.1016/j.bbr.2014.05.069. Epub 2014 Jun 10.

 


open Pubmed Abstract

Therapy for patients with dementia. Treatment strategies in the elderly

Jessen F.

 

Internist (Berl). 2014 Jul;55(7):769-74. doi: 10.1007/s00108-014-3465-2. German.

 


open Pubmed Abstract

N-acetyl-aspartate (NAA) as a correlate of pharmacological treatment in psychiatric disorders: A systematic review

Paslakis G, Träber F, Roberz J, Block W, Jessen F.

Eur Neuropsychopharmacol. 2014 Jul 4. pii: S0924-977X(14)00172-2. doi: 10.1016/j.euroneuro.2014.06.004. [Epub ahead of print]

 


open Pubmed Abstract

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, Sánchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C.

Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093.

 


open Pubmed Abstract

The significance of GBA for Parkinson's disease

Brockmann K, Berg D.

J Inherit Metab Dis. 2014 Jul;37(4):643-8. doi: 10.1007/s10545-014-9714-7. Epub 2014 Jun 4.

 


open Pubmed Abstract

An alternative hypothesis testing strategy for secondary phenotype data in case-control genetic association studies

Lutz SM, Hokanson JE, Lange C.

Front Genet. 2014 Jul 1;5:188. doi: 10.3389/fgene.2014.00188. eCollection 2014.

 


open Pubmed Abstract

Innate immune activation in neurodegenerative disease

Heneka MT, Kummer MP, Latz E.

Nat Rev Immunol. 2014 Jul;14(7):463-77. doi: 10.1038/nri3705.

 


open Pubmed Abstract

Encoding methods for B 1 + mapping in parallel transmit systems at ultra high field

Tse DH, Poole MS, Magill AW, Felder J, Brenner D, Jon Shah N.

J Magn Reson. 2014 Aug;245:125-32. doi: 10.1016/j.jmr.2014.06.006. Epub 2014 Jun 28.

 


open Pubmed Abstract

Ear2 deletion causes early memory and learning deficits in APP/PS1 mice

Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT.

J Neurosci. 2014 Jun 25;34(26):8845-54. doi: 10.1523/JNEUROSCI.4027-13.2014.

 


open Pubmed Abstract

Improved regeneration after femoral nerve injury in mice lacking functional T- and B-lymphocytes

Mehanna A, Szpotowicz E, Schachner M, Jakovcevski I.

Exp Neurol. 2014 Jun 23;261C:147-155. doi: 10.1016/j.expneurol.2014.06.012. [Epub ahead of print]

 


open Pubmed Abstract

Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes

Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, Rene R, Kornhuber J, Peters O, Luckhaus C, Jahn H, Hüll M, Rüther E, Wiltfang J, Lorenzo E, Gascon J, Lleó A, Lladó A, Campdelacreu J, Moreno F, Ahmadzadehfar H; Dementia Genetics Spanish Consortium (DEGESCO), Fortea J, Indakoetxea B, Heneka MT, Wetter A, Pastor MA, Riverol M, Becker T, Frölich L, Tárraga L, Boada M, Wagner M, Jessen F, Maier W, Clarimón J, López de Munain A, Ruiz A, Pastor P, Ramirez A.

Neurobiol Aging. 2014 Nov;35(11):2657.e13-9. doi: 10.1016/j.neurobiolaging.2014.06.018. Epub 2014 Jun 20.

 


open Pubmed Abstract