Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

Ferentinos P, Koukounari A, Power R, Rivera M, Uher R, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Ising M, Maier W, Mors O, Rietschel M, Preisig M, Binder EB, Aitchison KJ, Mendlewicz J, Souery D, Hauser J, Henigsberg N, Breen G, Craig IW, Farmer AE, Müller-Myhsok B, McGuffin P, Lewis CM.

Psychol Med. 2015 Feb 20:1-11. [Epub ahead of print]


open Pubmed Abstract

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

Ferentinos P, Koukounari A, Power R, Rivera M, Uher R, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Ising M, Maier W, Mors O, Rietschel M, Preisig M, Binder EB, Aitchison KJ, Mendlewicz J, Souery D, Hauser J, Henigsberg N, Breen G, Craig IW, Farmer AE, Müller-Myhsok B, McGuffin P, Lewis CM.

Psychol Med. 2015 Feb 20:1-11. [Epub ahead of print]

PMID: 25698070


open Pubmed Abstract

Prevalence of cerebral small-vessel disease in long-term breast cancer survivors exposed to both adjuvant radiotherapy and chemotherapy

Koppelmans V, Vernooij MW, Boogerd W, Seynaeve C, Ikram MA, Breteler MM, Schagen SB.

J Clin Oncol. 2015 Feb 20;33(6):588-93. doi: 10.1200/JCO.2014.56.8345. Epub 2015 Jan 5.


open Pubmed Abstract

Innate immunity in Alzheimer's disease

Heneka MT, Golenbock DT, Latz E.

Nat Immunol. 2015 Feb 17;16(3):229-236


open Pubmed Abstract

Gamma Power Reductions Accompany Stimulus-Specific Representations of Dynamic Events

Zhang H, Fell J, Staresina BP, Weber B, Elger CE, Axmacher N.

Curr Biol. 2015 Feb 12. pii: S0960-9822(15)00013-5. doi: 10.1016/j.cub.2015.01.011. [Epub ahead of print]

 


open Pubmed Abstract

Requirements for mutant and wild-type prion protein misfolding in vitro

Noble GP, Walsh DJ, Miller MB, Jackson WS, Supattapone S.

Biochemistry. 2015 Feb 10;54(5):1180-7. doi: 10.1021/bi501495j. Epub 2015 Jan 22.

 


open Pubmed Abstract

A transcriptional perspective on human macrophage biology

Schultze JL, Freeman T, Hume DA, Latz E.

Semin Immunol. 2015 Feb;27(1):44-50. doi: 10.1016/j.smim.2015.02.001. Epub 2015 Apr 3. Review.

PMID: 25843246


open Pubmed Abstract

Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug

Doeser A, Dickhof G, Reitze M, Uebachs M, Schaub C, Pires NM, Bonifácio MJ, Soares-da-Silva P, Beck H.

Brain. 2015 Feb;138(Pt 2):371-87.


open Pubmed Abstract

Synergistic activation of Toll-like receptor 8 by two RNA degradation products

Geyer M, Pelka K, Latz E.

Nat Struct Mol Biol. 2015 Feb;22(2):99-101. doi: 10.1038/nsmb.2967. No abstract available.

PMID: 25650902


open Pubmed Abstract

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type

Popp J, Wolfsgruber S, Heuser I, Peters O, Hüll M, Schröder J, Möller HJ, Lewczuk P, Schneider A, Jahn H, Luckhaus C, Perneczky R, Frölich L, Wagner M, Maier W, Wiltfang J, Kornhuber J, Jessen F.

Neurobiol Aging. 2015 Feb;36(2):601-7. doi: 10.1016/j.neurobiolaging.2014.10.031. Epub 2014 Oct 31.

 


open Pubmed Abstract

Selective processing of buildings and faces during working memory: The role of the ventral striatum

Haeger A, Lee H, Fell J, Axmacher N.

Eur J Neurosci. 2015 Feb;41(4):505-13. doi: 10.1111/ejn.12808. Epub 2014 Dec 22.

 


open Pubmed Abstract

Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model.

Schmöle AC, Lundt R, Ternes S, Albayram Ö, Ulas T, Schultze JL, Bano D, Nicotera P, Alferink J, Zimmer A.

Neurobiol Aging. 2015 Feb;36(2):710-9. doi: 10.1016/j.neurobiolaging.2014.09.019. Epub 2014 Sep 28.

 


open Pubmed Abstract

Predictors of hippocampal atrophy in critically ill patients

Lindlau A, Widmann CN, Putensen C, Jessen F, Semmler A, Heneka MT.

Eur J Neurol. 2015 Feb;22(2):410-5. doi: 10.1111/ene.12443. Epub 2014 Apr 12.

 


open Pubmed Abstract

Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors

Sarvestani ST, Stunden HJ, Behlke MA, Forster SC, McCoy CE, Tate MD, Ferrand J, Lennox KA, Latz E, Williams BR, Gantier MP.

Nucleic Acids Res. 2015 Jan 30;43(2):1177-88. doi: 10.1093/nar/gku1343. Epub 2014 Dec 24.

 


open Pubmed Abstract

PART is part of Alzheimer disease

Duyckaerts C, Braak H, Brion JP, Buée L, Del Tredici K, Goedert M, Halliday G, Neumann M, Spillantini MG, Tolnay M, Uchihara T.

Acta Neuropathol. 2015 May;129(5):749-56. doi: 10.1007/s00401-015-1390-7. Epub 2015 Jan 28


open Pubmed Abstract

Erratum: Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells

Bartesaghi S, Graziano V, Galavotti S, Henriquez NV, Betts J, Saxena J, A D, Karlsson A, Martins LM, Capasso M, Nicotera P, Brandner S, De Laurenzi V, Salomoni P.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1059-64. doi: 10.1073/pnas.1413165112. Epub 2015 Jan 12.

PMID: 25583481


open Pubmed Abstract

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells

Bartesaghi S, Graziano V, Galavotti S, Henriquez NV, Betts J, Saxena J, A D, Karlsson A, Martins LM, Capasso M, Nicotera P, Brandner S, De Laurenzi V, Salomoni P.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1059-64. doi: 10.1073/pnas.1413165112. Epub 2015 Jan 12.

 


open Pubmed Abstract

The inflammasomes and autoinflammatory syndromes

Broderick L, De Nardo D, Franklin BS, Hoffman HM, Latz E.

Annu Rev Pathol. 2015 Jan 24;10:395-424. doi: 10.1146/annurev-pathol-012414-040431. Epub 2014 Nov 19.

 


open Pubmed Abstract

Danger signaling in atherosclerosis

Zimmer S, Grebe A, Latz E.

Circ Res. 2015 Jan 16;116(2):323-340. Review.

 


open Pubmed Abstract

METAINTER: Meta-Analysis of multiple regression models in genome-wide association studies

Vaitsiakhovich T, Drichel D, Herold C, Lacour A, Becker T.

Bioinformatics. 2015 Jan 15;31(2):151-7. doi: 10.1093/bioinformatics/btu629. Epub 2014 Sep 23.

PMID: 25252781


open Pubmed Abstract

The immunoregulator soluble TACI Is released by ADAM10 and reflects B cell activation in autoimmunity

Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E.

J Immunol. 2015 Jan 15;194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10.

 


open Pubmed Abstract

Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8

Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T.

J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10.

 


open Pubmed Abstract

Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: A cross-sectional analysis of baseline data

Reetz K, Dogan I, Costa AS, Dafotakis M, Fedosov K, Giunti P, Parkinson MH, Sweeney MG, Mariotti C, Panzeri M, Nanetti L, Arpa J, Sanz-Gallego I, Durr A, Charles P, Boesch S, Nachbauer W, Klopstock T, Karin I, Depondt C, Vom Hagen JM, Schöls L, Giordano IA, Klockgether T, Bürk K, Pandolfo M, Schulz JB.

Lancet Neurol. 2015 Jan 2. pii: S1474-4422(14)70321-7. doi: 10.1016/S1474-4422(14)70321-7. [Epub ahead of print]

 


open Pubmed Abstract

Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: A cross-sectional analysis of baseline data

Reetz K, Dogan I, Costa AS, Dafotakis M, Fedosov K, Giunti P, Parkinson MH, Sweeney MG, Mariotti C, Panzeri M, Nanetti L, Arpa J, Sanz-Gallego I, Durr A, Charles P, Boesch S, Nachbauer W, Klopstock T, Karin I, Depondt C, Vom Hagen JM, Schöls L, Giordano IA, Klockgether T, Bürk K, Pandolfo M, Schulz JB.

Lancet Neurol. 2015 Jan 2. pii: S1474-4422(14)70321-7. doi: 10.1016/S1474-4422(14)70321-7. [Epub ahead of print]

 


open Pubmed Abstract

Elevated HbA1c is associated with increased risk of incident dementia in primary care patients

Ramirez A, Wolfsgruber S, Lange C, Kaduszkiewicz H, Weyerer S, Werle J, Pentzek M, Fuchs A, Riedel-Heller SG, Luck T, Mösch E, Bickel H, Wiese B, Prokein J, König HH, Brettschneider C, Breteler MM, Maier W, Jessen F, Scherer M.

J Alzheimers Dis. 2015 Jan 1;44(4):1203-12.


open Pubmed Abstract