Ryanodine receptor-2 upregulation and nicotine-mediated plasticity.

E Ziviani, G Lippi, D Bano, E Munarriz, S Guiducci, M Zoli, KW Young, P Nicotera; EMBO Journal. 2010 Nov 26; doi: EMBOJ.2010.279

open EMBO Journal Abstract

Different pathways lead to mitochondrial fragmentation during apoptotic and excitotoxic cell death in primary neurons.

KW Young, LGP Pinon, ETW Bampton, P Nicotera; J Biochem Mol Toxicol. 2010 Sep.

open PubMed Abstract

Abeta oligomers cause localized Ca2+ elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines.

H Zempel, E Thies, E mandelkow, E-M Mandelkow; J Neurosci. 2010 Sep 8.

open PubMed Abstract

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.

T Fiskerstrand, D H'Mida-Ben Brahim, S Johansson, A M'Zahem, BI Haukanes, N Drouot, J Zimmermann, AJ Cole, C Vedeler, C Bredrup, M Assoum, M Tazir, T Klockgether, A Hamri, VM Steen, H Boman, LA Bindoff, M Koenig, PM Knappskog; Am J Hum Genet. 2010 Sep 10.

open PubMed Abstract

Plasticity of voltage-gated ion channels in pyramidal cell dendrites

S Remy, H Beck, Y Yaari; Curr Opin Neurobiol. 2010 Aug 4. [Epub ahead of print]

open PubMed Abstract

Fyn-tau-amyloid: a toxic triad.

C Haass, E Mandelkow; Cell. 2010 Aug 6;142(3):356-8.

open PubMed Abstract

Human tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability.

S Wegmann, JJ Yu, S Chinnathambi, E-M Mandelkow, E Mandelkow, DJ Muller; J Biol Chem. 2010 Aug 27, Epub 2010 Jun 21.

open PubMed Abstract

Paraquat and Parkinson's disease.

C Berry, C La Vecchia, P Nicotera; Cell Death Differ. 2010 Jul; 17(7): 1115-25. Epub 2010 Jan 22.open PubMed Abstract

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.

H Hampel, R Frank, K Broich, SJ Teipel, RG Katz, J Hardy, K Herholz, AL Bokde, F Jessen, YC Hoessler, WR Sanhai, H Zetterberg, J Woodcock, K Blennow; Nat Rev Drug Discov. 2010 July; 9(7): 560-74

 open PubMed Abstract

[Course modifying therapy of Alzheimer's dementia].

MT Heneka; Nervenarzt. 2010 Jul;81(7):807-8, 810-4.

open PubMed Abstract

The relation of regional cerebral perfusion and atrophy in mild cognitive imperment (MCI) and early Alzheimer's dementia.

 C Luckhaus, M Cohnen, MO Fluss, M Janner, B Grass-Kapanke, SJ Teipel, M Grothe, H Hampel, O Peters, J Kornhuber, W Maier, T Supprian, W Gaebel, U Modder, HJ Wittsack; Psychiatry Res. 2010 Jul 30; 183(1): 44-51.

 open PubMed Abstract

Mitochondrial fragmentation and neuronal cell death in response to the Bcl-2/Bcl-x(L)/Bcl-w antagonist ABT-737.

KW Young, LG Piñón, D Dhiraj, D Twiddy, M Macfarlane, J Hickman, P Nicotera; Neuropharmacology. 2010 Jun.

open PubMed Abstract

MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening.

H Farhan, MW Wendeler, S Mitrovic, E Fava, Y Silberberg, R Sharan, M Zerial, HP Hauri; J CellBiol. 2010 Jun 14.

open PubMed Abstract

Loss of thymidine kinase 2 alters neuronal bioenergetics and leads to neurodegeneration.

S Bartesaghi, J Betts-Henderson, K Cain, D Dinsdale, X Zhou, A Karlsson, P Salomoni, P Nicotera; Hum Mol Genet. 2010 May 1;19(9):1669-77. Epub 2010 Feb 1.

open PubMed Abstract

Nuclear pore complex during neuronal degeneration: Cracking the last barrier!

D Bano, MO Hengartner, P Nicotera; Nucleus; 2010 March/April.

open Nucleus Abstract

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

MT Heneka, F Nadrigny, T Regen, A Martinez-Hernandez, L Dumitrescu-Ozimek, D Terwel, D Jardanhazi-Kurutz, J Walter, F Kirchhoff, UK Hanisch, MP Kummer; Proc Natl Acad Sci USA. 2010 Mar 15.

open PubMed Abstract

miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro.

H Chen, R Shalom-Feuerstein, J Riley, SD Zhang, P Tucci, M Agostini, D Aberdam, RA Knight, G Genchi, P Nicotera, G Melino, M Vasa-Nicotera; Biochem Biophys Res Commun. 2010 Mar 15. [Epub ahead of print]

open PubMed Abstract

Feasible and Successful: Genome-Wide Interaction Analysis Involving All 1.9 x 1011 Pair-Wise Interaction Tests

M Steffens, T Becker, T Sander, R Fimmers, C Herold, DA Holler, C Leu, S Herms, S Cichon, B Bohn, T Gerstner, M Griebel, MM Nöthen, TF Wienker, MP Baur; Hum Hered. 2010 Mar 31; 69(4): 268-284. [Epub ahead of print]

open PubMed Abstract

Cell Death and Disease: a new journal for a central area of pathophysiology.

G. Kroemer, P. Nicotera, G. Melino, Cell Death Dis. 2010 Jan;1(1):e11.

open PubMed Abstract

The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development

J Betts-Henderson, S Bartesaghi, M Crosier, S Lindsay, HL Chen, P Salomoni, I Gottlob and P Nicotera; Hum. Mol. Genet. 2010 Jan 15; 19(2): 342-351.

open PubMed Abstract 

Sporadic ataxia with adult onset: classification and diagnostic criteria.

T Klockgether; Lancet Neurol. 2010 Jan; 9(1): 94-104.

open PubMed Abstract

Alteration of the nuclear pore complex in Ca(2+)-mediated cell death.

D Bano, D Dinsdale, A Cabrera-Socorro, S Maida, N Lambacher, B McColl, E Ferrando-May, MO Hengartner, P Nicotera; Cell Death Differ. 2010 Jan;17(1):119-33.

open PubMed Abstract

Paraquat and Parkinson's disease

C Berry, C La Vecchia, P Nicotera; Cell Death Differ. 2010 Jan 22.

open PubMed Abstract

INTERSNP: genome-wide interaction analysis guided by a priori information.

C Herold, M Steffens, FF Brockschmidt, MP Baur, T Becker; Bioinformatics. 2009 Dec 15.

open PubMed Abstract

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