Weekly treatment of 2-hydroxypropyl-β-cyclodextrin improves intracellular cholesterol levels in LDL receptor knockout mice

Walenbergh SM, Houben T, Hendrikx T, Jeurissen ML, van Gorp PJ, Vaes N, Olde Damink SW, Verheyen F, Koek GH, Lütjohann D, Grebe A, Latz E, Shiri-Sverdlov R.

Int J Mol Sci. 2015 Sep 2;16(9):21056-69


open Pubmed Abstract 

Neuronal Network Oscillations in Neurodegenerative Diseases

Nimmrich V, Draguhn A, Axmacher N.

Neuromolecular Med. 2015 Sep;17(3):270-84. doi: 10.1007/s12017-015-8355-9. Epub 2015 Apr 29.


open Pubmed Abstract

Is the Short Form of the Mini-Mental State Examination (MMSE) a better screening instrument for dementia in older primary care patients than the original MMSE? Results of the German study on ageing, cognition, and dementia in primary care patients (AgeCoDe

Stein J, Luppa M, Kaduszkiewicz H, Eisele M, Weyerer S, Werle J, Bickel H, Mösch E, Wiese B, Prokein J, Pentzek M, Fuchs A, König HH, Brettschneider C, Heser K, Wagner M, Riedel-Heller SG, Scherer M, Maier W.

Psychol Assess. 2015 Sep;27(3):895-904. doi: 10.1037/pas0000076. Epub 2015 Mar 30.


open Pubmed abstract 

Stimulation of the Dopaminergic Midbrain as a Behavioral Reward in Instrumentally Conditioned Monkeys

Lovell JM, Mylius J, Scheich H, Brosch M.

Brain Stimul. 2015 Sep-Oct;8(5):868-74. doi: 10.1016/j.brs.2015.04.007. Epub 2015 May 16.


open Pubmed Abstract

Functional disability and quality of life decrements in mental disorders: Results from the Mental Health Module of the German Health Interview and Examination Survey for Adults (DEGS1-MH)

Mack S, Jacobi F, Beesdo-Baum K, Gerschler A, Strehle J, Höfler M, Busch MA, Maske U, Hapke U, Gaebel W, Zielasek J, Maier W, Wittchen HU.

Eur Psychiatry. 2015 Sep;30(6):793-800. doi: 10.1016/j.eurpsy.2015.06.003. Epub 2015 Jul 10.


open Pubmed Abstract

Computational dissection of human episodic memory reveals mental process-specific genetic profiles.

Luksys G, Fastenrath M, Coynel D, Freytag V, Gschwind L, Heck A, Jessen F, Maier W, Milnik A, Riedel-Heller SG, Scherer M, Spalek K, Vogler C, Wagner M, Wolfsgruber S, Papassotiropoulos A, de Quervain DJ.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4939-48. doi: 10.1073/pnas.1500860112. Epub 2015 Aug 10.


open PubMed abstract

Age-related changes in the endocannabinoid system in the mouse hippocampus

Piyanova A, Lomazzo E, Bindila L, Lerner R, Albayram O, Ruhl T, Lutz B, Zimmer A, Bilkei-Gorzo A.

Mech Ageing Dev. 2015 Sep


open Pubmed abstract

Human Hippocampal Dynamics during Response Conflict

Oehrn CR, Baumann C, Fell J, Lee H, Kessler H, Habel U, Hanslmayr S, Axmacher N.

Curr Biol. 2015 Aug 31;25(17):2307-13. doi: 10.1016/j.cub.2015.07.032. Epub 2015 Aug 20.


open Pubmed abstract

Folding of the Tau Protein on Microtubules

Kadavath H, Jaremko M, Jaremko Ł, Biernat J, Mandelkow E, Zweckstetter M.

Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10347-51. doi: 10.1002/anie.201501714. Epub 2015 Jun 19.


open Pubmed Abstract

Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families

Park S, Lee S, Lee Y, Herold C, Hooli B, Mullin K, Park T, Park C, Bertram L, Lange C, Tanzi R, Won S.

BMC Med Genet. 2015 Aug 19;16:62. doi: 10.1186/s12881-015-0198-6.


open Pubmed abstract

Age-related changes in the endocannabinoid system in the mouse hippocampus

Piyanova A, Lomazzo E, Bindila L, Lerner R, Albayram O, Ruhl T, Lutz B, Zimmer A, Bilkei-Gorzo A.

Mech Ageing Dev. 2015 Aug 13;150:55-64. doi: 10.1016/j.mad.2015.08.005. [Epub ahead of print]

 


open Pubmed Abstract

Structural Impact of Tau Phosphorylation at Threonine 231

Schwalbe M, Kadavath H, Biernat J, Ozenne V, Blackledge M, Mandelkow E, Zweckstetter M.

Structure. 2015 Aug 4;23(8):1448-58. doi: 10.1016/j.str.2015.06.002. Epub 2015 Jul 9.


open Pubmed Abstract

Smaller than expected cognitive deficits in schizophrenia patients from the population-representative ABC catchment cohort

Lennertz L, An der Heiden W, Kronacher R, Schulze-Rauschenbach S, Maier W, Häfner H, Wagner M.

Eur Arch Psychiatry Clin Neurosci. 2015 Aug 2. [Epub ahead of print]


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Regional Pattern of Dementia and Prevalence of Hearing Impairment in Germany

Teipel S, Fritze T, Ovari A, Buhr A, Kilimann I, Witt G, Pau HW, Doblhammer G.

J Am Geriatr Soc. 2015 Aug;63(8):1527-33. doi: 10.1111/jgs.13561. Epub 2015 Jul 22.


open Pubmed abstract

Risk of dementia in elderly patients with the use of proton pump inhibitors

Haenisch B, von Holt K, Wiese B, Prokein J, Lange C, Ernst A, Brettschneider C, König HH, Werle J, Weyerer S, Luppa M, Riedel-Heller SG, Fuchs A, Pentzek M, Weeg D, Bickel H, Broich K, Jessen F, Maier W, Scherer M.

Eur Arch Psychiatry Clin Neurosci. 2015 Aug;265(5):419-28. doi: 10.1007/s00406-014-0554-0. Epub 2014 Oct 24.

PMID: 25341874


open Pubmed Abstract

Oxytocin facilitates the extinction of conditioned fear in humans

Eckstein M, Becker B, Scheele D, Scholz C, Preckel K, Schlaepfer TE, Grinevich V, Kendrick KM, Maier W, Hurlemann R.

Biol Psychiatry. 2015 Aug 1;78(3):194-202. doi: 10.1016/j.biopsych.2014.10.015. Epub 2014 Oct 30.

PMID: 25542304


open Pubmed Abstract

Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency

Doss S, Rinnenthal JL, Schmitz-Hübsch T, Brandt AU, Papazoglou S, Lux S, Maul S, Würfel J, Endres M, Klockgether T, Minnerop M, Paul F.

J Neurol. 2015 Aug;262(8):1927-35. doi: 10.1007/s00415-015-7788-2. Epub 2015 Jun 5.


open Pubmed Abstract

Modulation of glycosaminoglycans affects PrPSc metabolism but does not block PrPSc uptake

Wolf H, Graßmann A, Bester R, Hossinger A, Möhl C, Paulsen L, Groschup MH, Schätzl H, Vorberg I.

J Virol. 2015 Oct;89(19):9853-64. doi: 10.1128/JVI.01276-15. Epub 2015 Jul 22.


open PubMed abstract

Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

Korkola JE, Collisson EA, Heiser L, Oates C, Bayani N, Itani S, Esch A, Thompson W, Griffith OL, Wang NJ, Kuo WL, Cooper B, Billig J, Ziyad S, Hung JL, Jakkula L, Feiler H, Lu Y, Mills GB, Spellman PT, Tomlin C, Mukherjee S, Gray JW.

PLoS One. 2015 Jul 16;10(7):e0133219. doi: 10.1371/journal.pone.0133219. eCollection 2015.


open PubMed abstract

Prevalence and determinants of overweight and obesity in old age in Germany

Hajek A, Lehnert T, Ernst A, Lange C, Wiese B, Prokein J, Weyerer S, Werle J, Pentzek M, Fuchs A, Luck T, Bickel H, Mösch E, Heser K, Wagner M, Maier W, Scherer M, Riedel-Heller SG, König HH; AgeCoDe Study Group.

BMC Geriatr. 2015 Jul 14;15:83. doi: 10.1186/s12877-015-0081-5.

PMID: 26170016


open Pubmed Abstract

Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease

Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR.

PLoS One. 2015 Jul 13


open Pubmed abstract

Mast cell activation disease: An underappreciated cause of neurologic and psychiatric symptoms and diseases

Afrin LB, Pöhlau D, Raithel M, Haenisch B, Dumoulin FL, Homann J, Mauer UM, Harzer S, Molderings GJ.

Brain Behav Immun. 2015 Jul 8. pii: S0889-1591(15)00236-6. doi: 10.1016/j.bbi.2015.07.002. [Epub ahead of print] Review.

PMID: 26162709


open Pubmed Abstract

The preclinical stage of spinocerebellar ataxias

Maas RP, van Gaalen J, Klockgether T, van de Warrenburg BP.

Neurology. 2015 Jul 7;85(1):96-103. doi: 10.1212/WNL.0000000000001711. Epub 2015 Jun 10. Review.

PMID: 26062625


open Pubmed Abstract

Investigation of the role of TCF4 rare sequence variants in schizophrenia

Basmanav FB, Forstner AJ, Fier H, Herms S, Meier S, Degenhardt F, Hoffmann P, Barth S, Fricker N, Strohmaier J, Witt SH, Ludwig M, Schmael C, Moebus S, Maier W, Mössner R, Rujescu D, Rietschel M, Lange C, Nöthen MM, Cichon S.

Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168(5):354-62. doi: 10.1002/ajmg.b.32318. Epub 2015 May 22.

PMID: 26010163


open Pubmed Abstract

Investigation of the role of TCF4 rare sequence variants in schizophrenia

Basmanav FB, Forstner AJ, Fier H, Herms S, Meier S, Degenhardt F, Hoffmann P, Barth S, Fricker N, Strohmaier J, Witt SH, Ludwig M, Schmael C, Moebus S, Maier W, Mössner R, Rujescu D, Rietschel M, Lange C, Nöthen MM, Cichon S.

Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168(5):354-62. doi: 10.1002/ajmg.b.32318. Epub 2015 May 22.

PMID: 26010163


open Pubmed Abstract