Translationale Demenzforschung
Prof. Dr. Anja Schneider
Gruppenleiterin
Direktorin der Klinik für Neurodegenerative Erkrankungen und Gerontopsychiatrie, Universitätsklinik Bonn
Venusberg-Campus 1, Gebäude 99
(ehemals Sigmund-Freud-Str. 27)
53127 Bonn

anja.schneider@dzne.de
 +49 228 43302-450

Publikationen

Die vollständige Publikationsliste findet manh hier.

Ana Martinez Hernandez, Hendrik Urbanke, Alan L Gillman, Joon Lee, Sergey Ryazanov, Hope Y Agbemenyah, Eva Benito, Gaurav Jain, Lalit Kaurani, Gayane Grigorian, Andrei Leonov, Nasrollah Rezaei-Ghaleh, Petra Wilken, Fernando Teran Arce, Jens Wagner, Martin Fuhrman, Mario Caruana, Angelique Camilleri, Neville Vassallo, Markus Zweckstetter, Roland Benz, Armin Giese, Anja Schneider, Martin Korte, Ratnesh Lal, Christian Griesinger, Gregor Eichele, Andre Fischer. The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine. 2017 Dec 31; 10:32-47. doi: 10.15252/emmm.201707825
Pellkofer H, Ihler F, Weiss BG, Trothe J, Kadavath H, Chongtham M, Kunadt M, Riedel D, Lornsen F, Wilken P, Bartels C, Hirschel S, Russo SG, Stransky E, Trojan L, Schmidt B, Mandelkow E, Zweckstetter M, Canis M, Schneider A. Evaluation of the methoxy-X04 derivative BSC4090 for diagnosis of prodromal and early Alzheimer's disease from bioptic olfactory mucosa. Eur Arch Psychiatry Clin Neurosci. 2018 Nov 12; doi: 10.1007/s00406-018-0955-6
Gong J, Szego ÉM, Leonov A, Benito E, Becker S, Fischer A, Zweckstetter M, Outeiro T, Schneider A. Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism. J Neurosci. 2019 May 08; 39:3752-3769. doi: 10.1523/JNEUROSCI.2070-18.2019
Tjasa Lepko, Melanie Pusch, Tamara Müller, Dorothea Schulte, Janina Ehses, Michael Kiebler, Julia Hasler, Hagen B. Huttner, Roosmarijn E. Vandenbroucke, Charysse Vandendriessche, Micha Modic, Ana Martin-Villalba, Sheng Zhao, Enric LLorens-Bobadilla, Anja Schneider, Andre Fischer, Christopher T. Breunig, Stefan H. Stricker, Magdalena Götz and Jovica Ninkovic. Choroid Plexus Releases miR-204 Regulating the Number of Neural Stem Cells in the Adult Brain. EMBO. ; in press
Bartels C, Wolfsgruber S, Wagner M, Ehrenreich H, Schneider A. Impact of selective serotonin reuptake inhibitor therapy on risk of conversion from mild cognitive impairment to Alzheimer’s dementia in individuals with previous depression. Am J Psychiatry. 2017 Nov 28; doi: 10.1176/appi.ajp.2017.17040404
Yipeng Wang, Varun Balaji, Senthilvelrajan Kaniyappan, Lars Krüger, Stephan Irsen, Katharina Tepper, Ramreddy Chandupatla, Walter Maetzler, Anja Schneider, Eckhard Mandelkow, Eva-Maria Mandelkow. The release and trans-synaptic transmission of Tau via exosomes. Molecular Neurodegeneration. 2017 Jan 12; 12 doi: 10.1186/s13024-016-0143-y
Anne Stuendl, Marcel Kunadt, Niels Kruse, Claudia Bartels, Wiebke Moebius, Karin M. Danzer, Brit Mollenhauer, Anja Schneider. Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain. 2016 Jan 31; 139:481-494. doi: 10.1093/brain/awv346
William I. Zhang, Gregory Antonios, Alberto Rabano, Thomas A. Bayer, Anja Schneider, Silvio O. Rizzoli. Super-Resolution Microscopy of Cerebrospinal Fluid Biomarkers as a Tool for Alzheimer's Disease Diagnostics. Journal of Alzheimer's Disease. 2015 Jun 25; 46:1007-1020. doi: 10.3233/JAD-150064
Kunadt M, Eckermann K, Strauss K, Rai S, Kügler S, Stündl A, Lockhart LF, Schwalbe M, Krumova P, Oliveira L, Bähr M, Möbius W, Ludolph AC, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Freischmidt A, Feiler M, Danzer KM, Zweckstetter M, Jovin T, Simons M, Weishaupt JH, Schneider A. Sumoylation regulates exosomal sorting of -Synuclein for extracellular release. Acta Neuropathologica. 2015 May 01; 129:695-713. doi: 10.1007/s00401-015-1408-1
Ulusoy A, Musgrove RE, Rusconi R, Klinkenberg M, Helwig M, Schneider A, Di Monte DA. Neuron-to-neuron alpha-synuclein propagation is dependent on neuronal integrity. Acta Neuropathologica Comm. 2015 Mar 24; 3:13. doi: 10.1186/s40478-015-0198-y
Nasrollah Rezaei-Ghaleh, Mehriar Amininasab, Karin Giller, Sathish Kumar, Anne Stündl, Anja Schneider, Stefan Becker, Jochen Walter, Markus Zweckstetter. Turn plasticity distinguishes different modes of amyloid-β aggregation. Journal of the American Chemical Society. 2014 Apr 01; 136:4913-4919. doi: 10.1021/ja411707y
Hammer, Stepniak, Schneider, Papiol, Tantra, Begemann, Sirén, Pardo, Sperling, Mohd Jofrry, Gurvich, Jensen, Ostmeier, Lühder, Probst, Martens, Gillis, Saher, Assogna, Spalletta, Stöcker, Schulz, Nave, Ehrenreich. Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity. Molecular Psychiatry. 2014 Sep 30; 19:1143-1149. doi: 10.1038/mp.2013.110
Carsten Frühbeis, Dominik Fröhlich, Wen Ping Kuo, Jesa Amphornrat, Sebastian Thilemann, Aiman S. Saab, Frank Kirchhoff, Wiebke Möbius, Sandra Goebbels, Klaus-Armin Nave, Anja Schneider, Mikael Simons, Matthias Klugmann, Jacqueline Trotter, Eva-Maria Krämer-Albers. Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte-Neuron Communication. PLoS Biology. 2013 Jun 30; 11 doi: 10.1371/journal.pbio.1001604
Strauss K., Goebels C., Moebius W., Weiss S., Runz H., Feussner I., Simons M., Schneider A. Exosome secretion bypasses lysosomal storage of cholesterol in Niemann-Pick type C disease. J Biol Chem. 2010 Aug 20; 285:26279-88.
Rajendran L., Schneider A., Schlechtingen G., Weidlich S., Ries J., Braxmeier T., Schwille P., Schulz J.B., Schroeder C., Simons M., Jennings G., Knoelker H.J., Simons K. Efficient inhibition of the Alzheimer’s disease β-secretase by membrane targeting. Science. 2008 Apr 25; 320:520-3.

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