Jonas Neher
Experimentelle Neuroimmunologie
Dr. Jonas Neher
Gruppenleiter
Otfried-Müller-Str. 23
72076 Tübingen

jonas.neher@dzne.de
 +49 7071 925-4351

Publikationen

Die vollständige Publikationsliste findet man hier.

Neher JJ, Cunningham C. Priming Microglia for Innate Immune Memory in the Brain. Trends in Immunology. 2019 Apr 01; 40:358-74. doi: 10.1016/j.it.2019.02.001
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Carola Focke, Brigitte Nuscher, Monica Xiong, Alireza Ghasemigharagoz, Natalie Katzmarski, Susanne Krasemann, Stefan F. Lichtenthaler, Stephan A. Müller, Alessio Colombo, Laura Sebastian Monasor, Sabina Tahirovic, Jochen Herms, Michael Willem, Nadine Pettkus, Oleg Butovsky, Peter Bartenstein, Dieter Edbauer, Axel Rominger, Ali Ertürk, Stefan A. Grathwohl, Jonas J. Neher, David M. Holtzman, Melanie Meyer-Luehmann, Christian Haass. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. 2019 Jan 31; 22:191-204. doi: 10.1038/s41593-018-0296-9
Skodras AA, Hefendehl J, Neher JJ. Long-term in vivo imaging of individual microglia cells. Methods in Molecular Biology. 2019 Jan 01; 2034:177-189. doi: 10.1007/978-1-4939-9658-2_13
Varvel NH, Ransohoff RM, Neher JJ. Functional Analysis of Brain-engrafted Monocytes after Microglial Ablation in Mouse Models. Methods in Molecular Biology. 2019 Jan 01; 2034:293-301. doi: 10.1007/978-1-4939-9658-2_22
Nichols MR, St-Pierre M-K, Wendeln A-C, Makoni NJ, Gouwens LK, Garrad EC, Sohrabi M, Neher JJ, Tremblay M-È, Combs CK. Inflammatory mechanisms in neurodegeneration. Journal of Neurochemistry. 2019 Jun 01; 149:562-81. doi: 10.1111/jnc.14674
Ann-Christin Wendeln, Karoline Degenhardt, Lalit Kaurani, Michael Gertig, Thomas Ulas, Gaurav Jain, Jessica Wagner, Lisa M. Häsler, Katleen Wild, Angelos Skodras, Thomas Blank, Ori Staszewski, Moumita Datta, Tonatiuh Pena Centeno, Vincenzo Capece, Md. Rezaul Islam, Cemil Kerimoglu, Matthias Staufenbiel, Joachim L. Schultze, Marc Beyer, Marco Prinz, Mathias Jucker, André Fischer & Jonas J. Neher. Innate immune memory in the brain shapes neurological disease hallmarks. Nature, advanced online publication. 2018 Apr 11; 556:332-338. doi: 10.1038/s41586-018-0023-4
Petra Füger, Jasmin K. Hefendehl, Karthik Veeraraghavalu, Ann-Christin Wendeln, Christine Schlosser, Ulrike Obermüller, Bettina M. Wegenast-Braun, Jonas J. Neher, Peter Martus, Shinichi Kohsaka, Martin Thunemann, Robert Feil, Sangram S. Sisodia, Angelos Skodras, Mathias Jucker. Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging. Nature Neuroscience. 2017 Sep 30; 20:1371-1376. doi: 10.1038/nn.4631
Harach, Marungruang, Duthilleul, Cheatham, Mc Coy, Frisoni, Neher, Fåk, Jucker, Lasser, Bolmont. Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota. Scientific Reports. 2017 Feb 07; 7 doi: 10.1038/srep41802
Julius V. Emmrich, Jonas J. Neher, Philipp Boehm-Sturm, Matthias Endres, Ulrich Dirnagl, Christoph Harms. Stage 1 Registered Report: Effect of deficient phagocytosis on neuronal survival and neurological outcome after temporary middle cerebral artery occlusion (tMCAo). F1000Research. 2016 Dec 31; 6 doi: 10.12688/f1000research.12537.1
Varvel NH, Neher JJ, Bosch A, Wang W, Ransohoff RM, Miller RJ, Dingledine R. Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus. Proc Natl Acad Sci U S A. 2016 Sep 20; 113:E5665-74. doi: 10.1073/pnas.1604263113
Nicholas H. Varvel, Stefan A. Grathwohl, Karoline Degenhardt, Claudia Resch, Andrea Bosch, Mathias Jucker, Jonas J. Neher. Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease. Journal of Experimental Medicine. 2014 Dec 31; 212:1803-1809. doi: 10.1084/jem.20150478
Emmrich JV, Ejaz S, Neher JJ, Williamson DJ, Baron J-C. Regional distribution of selective neuronal loss and microglial activation across the MCA territory after transient focal ischemia: quantitative versus semiquantitative systematic immunohistochemical assessment. Journal of Cerebral Blood Flow & Metabolism. 2015 Jan 01; 35:20-7. doi: 10.1038/jcbfm.2014.181
Brelstaff J, Ossola B, Neher JJ, Klingstedt T, Nilsson KPR, Goedert M, Spillantini MG, Tolkovsky AM. The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice. Frontiers in Neuroscience. 2015 Jan 01; 9 doi: 10.3389/fnins.2015.00184
Guy C. Brown, Jonas J. Neher. Microglial phagocytosis of live neurons. Nature Reviews Neuroscience. 2014 Mar 31; 15:209-216. doi: 10.1038/nrn3710
Neher JJ, Emmrich JV, Fricker M, Mander PK, Théry C, Brown GC. Phagocytosis executes delayed neuronal death after focal brain ischemia. Proc Natl Acad Sci U S A. 2013 Oct 22; 110:E4098-107. doi: 10.1073/pnas.1308679110

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