Publikationen


Janine Diehl-Schmid, Abigail Licata, Oliver Goldhardt, Hans Förstl, Igor Yakushew, Markus Otto, Sarah Anderl-Straub, Ambros Beer, Albert Christian Ludolph, Georg Bernhard Landwehrmeyer, Johannes Levin, Adrian Danek, Klaus Fliessbach, Annika Spottke, Klaus Fassbender, Epameinondas Lyros, Johannes Prudlo, Bernd Joachim Krause, Alexander Volk, Dieter Edbauer, Matthias Leopold Schroeter, Alexander Drzezga, Johannes Kornhuber, Martin Lauer, Nibal Ackl, Christine v. Arnim, Joachim Brumberg, Florian Gärtner, Holger Jahn, Elisabeth Kasper, Jan Kassubek, Catharina Prix, Lina Riedl, Carola Roßmeier, Sonja Schönecker, Elisa Semler, Stefan Teipel, Christine Westerteicher, Elisabeth Wlasich, Timo Grimmer. FDG-PET underscores the key role of the thalamus in frontotemporal lobar degeneration caused by C9ORF72 mutations. Translational Psychiatry. 2019 Nov 30; 9 doi: 10.1038/s41398-019-0381-1
Maria Carolina Dalmasso, Luis Ignacio Brusco, Natividad Olivar, Carolina Muchnik, Claudia Hanses, Esther Milz, Julian Becker, Stefanie Heilmann-Heimbach, Per Hoffmann, Federico A. Prestia, Pablo Galeano, Mariana Soledad Sanchez Avalos, Luis Eduardo Martinez, Mariana Estela Carulla, Pablo Javier Azurmendi, Cynthia Liberczuk, Cristina Fezza, Marcelo Sampaño, Maria Fierens, Guillermo Jemar, Patricia Solis, Nancy Medel, Julieta Lisso, Zulma Sevillano, Paolo Bosco, Paola Bossù, Gianfranco Spalletta, Daniela Galimberti, Michelangelo Mancuso, Benedetta Nacmias, Sandro Sorbi, Patrizia Mecocci, Alberto Pilotto, Paolo Caffarra, Francesco Panza, Maria Bullido, Jordi Clarimon, Pascual Sánchez-Juan, Eliecer Coto, Florentino Sanchez-Garcia, Caroline Graff, Martin Ingelsson, Céline Bellenguez, Eduardo Miguel Castaño, Claudia Kairiyama, Daniel Gustavo Politis, Silvia Kochen, Horacio Scaro, Wolfgang Maier, Frank Jessen, Carlos Alberto Mangone, Jean-Charles Lambert, Laura Morelli, Alfredo Ramirez. Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease. Translational Psychiatry. 2019 Nov 30; 9 doi: 10.1038/s41398-019-0394-9
Claudia Schob, Fabio Morellini, Ora Ohana, Lidia Bakota, Mariya V. Hrynchak, Roland Brandt, Marco D. Brockmann, Nicole Cichon, Henrike Hartung, Ileana L. Hanganu-Opatz, Vanessa Kraus, Sarah Scharf, Irm Herrmans-Borgmeyer, Michaela Schweizer, Dietmar Kuhl, Markus Wöhr, Karl J. Vörckel, Julia Calzada-Wack, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Craig C. Garner, Hans-Jürgen Kreienkamp, Stefan Kindler. Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice. Translational Psychiatry. 2019 Nov 30; 9 doi: 10.1038/s41398-018-0327-z
Sarah C. Starossom, Juliana Campo Garcia, Tim Woelfle, Silvina Romero-Suarez, Marta Olah, Fumihiro Watanabe, Li Cao, Ada Yeste, John J. Tukker, Francisco J. Quintana, Jaime Imitola, Franziska Witzel, Dietmar Schmitz, Markus Morkel, Friedemann Paul, Carmen Infante-Duarte, Samia J. Khoury. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nature Communications. 2019 Nov 30; 10 doi: 10.1038/s41467-018-08140-7
Eric E. Smith, Geert Jan Biessels, François De Guio, Frank Erik de Leeuw, Simon Duchesne, Marco Düring, Richard Frayne, M. Arfan Ikram, Eric Jouvent, Bradley J. MacIntosh, Michael J. Thrippleton, Meike W. Vernooij, Hieab Adams, Walter H. Backes, Lucia Ballerini, Sandra E. Black, Christopher Chen, Rod Corriveau, Charles DeCarli, Steven M. Greenberg, M. Edip Gurol, Michael Ingrisch, Dominic Job, Bonnie Y.K. Lam, Lenore J. Launer, Jennifer Linn, Cheryl R. McCreary, Vincent C.T. Mok, Leonardo Pantoni, G. Bruce Pike, Joel Ramirez, Yael D. Reijmer, Jose Rafael Romero, Stefan Ropele, Natalia S. Rost, Perminder S. Sachdev, Christopher J.M. Scott, Sudha Seshadri, Mukul Sharma, Steven Sourbron, Rebecca M.E. Steketee, Richard H. Swartz, Robert van Oostenbrugge, Matthias van Osch, Sanneke van Rooden, Anand Viswanathan, David Werring, Martin Dichgans, Joanna M. Wardlaw. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 2019 Nov 30; 11:191-204. doi: 10.1016/j.dadm.2019.01.002
Pascale Baden, Cong Yu, Michela Deleidi. Insights into GBA Parkinson's disease pathology and therapy with induced pluripotent stem cell model systems. Neurobiology of Disease. 2019 Jun 30; 127:1-12. doi: 10.1016/j.nbd.2019.01.023
Matthias Höllerhage, Natascha Fussi, Thomas W. Rösler, Wolfgang Wurst, Christian Behrends, Günter U. Höglinger. Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons. Neuropharmacology. 2019 Apr 30; 149:13-26. doi: 10.1016/j.neuropharm.2019.01.023
Hilton BJ, Blanquie O, Tedeschi A, Bradke F. High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing. Nat Protoc. 2019 Apr 19; 14:1235-1260. doi: 10.1038/s41596-019-0140-z
Steurner T, Tatarnikova A, Mueller J, Schaffran B, Cuntz H, Zhang Y, Nemethova M, Bogdan S, Small V and Tavosanis G.. Transient localization of the Arp2/3 complex initiates neuronal dendrite branching in vivo. Development 2019. 2019 Apr 04; 146: dev171397 doi: 10.1242/dev.171397
Cordula Rakers, Melvin Schleif, Nelli Blank, Hana Matušková, Thomas Ulas, Kristian Händler, Santiago Valle Torres, Toni Schumacher, Khalid Tai, Joachim L. Schultze, Walker S. Jackson, Gabor C. Petzold. Stroke target identification guided by astrocyte transcriptome analysis. GLIA. 2019 Mar 31; 67:619-633. doi: 10.1002/glia.23544
Jonathan Vöglein, Soheyl Noachtar, Eric McDade, Kimberly A. Quaid, Stephen Salloway, Bernardino Ghetti, James Noble, Sarah Berman, Jasmeer Chhatwal, Hiroshi Mori, Nick Fox, Ricardo Allegri, Colin L. Masters, Virginia Buckles, John M. Ringman, Martin Rossor, Peter R. Schofield, Reisa Sperling, Mathias Jucker, Christoph Laske, Katrina Paumier, John C. Morris, Randall J. Bateman, Johannes Levin, Adrian Danek. Seizures as an early symptom of autosomal dominant Alzheimer's disease. Neurobiology of Aging. 2019 Mar 31; 76:18-23. doi: 10.1016/j.neurobiolaging.2018.11.022
Marcus Pickhardt, Michele Tassoni, Philip Denner, Birgit Kurkowsky, Ana Kitanovic, Christoph Möhl, Eugenio Fava, Eckhard Mandelkow. Screening of a neuronal cell model of tau pathology for therapeutic compounds. Neurobiology of Aging. 2019 Mar 31; 76:24-34. doi: 10.1016/j.neurobiolaging.2018.11.026
Enrico Premi, Vince D. Calhoun, Matteo Diano, Stefano Gazzina, Maura Cosseddu, Antonella Alberici, Silvana Archetti, Donata Paternicò, Roberto Gasparotti, John van Swieten, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris Butler, Simon Ducharme, Alex Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Giovanni Frisoni, Stefano Cappa, Sandro Sorbi, Alessandro Padovani, Jonathan D. Rohrer, Barbara Borroni. The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint. NeuroImage. 2019 Mar 31; 189:645-654. doi: 10.1016/j.neuroimage.2019.01.080
Sgobio C, Sun L, Ding J, Herms J, Lovinger DM, Cai H. In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model. Sci Rep. 2019 Mar 19; 9:4857. doi: 10.1038/s41598-019-41091-7
Cavaliere, F., Fornarelli, A., Bertan, F., Russo, R., Marsal-Cots, A., Morrone, L.A., Adornetto, A., Corasaniti, M.T., Bano, D., Bagetta, G., et al. The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux. Sci Rep. 2019 Mar 09; 9:4881. doi: 10.1038/s41598-019-40887-x
Andreas Traschütz, Markus P. Kummer, Stephanie Schwartz, Michael T. Heneka. Variability and temporal dynamics of novel object recognition in aging male C57BL/6 mice. Behavioural Processes. 2019 Mar 06; 157:711-716. doi: 10.1016/j.beproc.2017.11.009
Lydia Reinhardt, Susanne Kordes, Peter Reinhardt, Michael Glatza, Matthias Baumann, Hannes C.A. Drexler, Sascha Menninger, Gunther Zischinsky, Jan Eickhoff, Claudia Fröb, Prabesh Bhattarai, Guruchandar Arulmozhivarman, Lara Marrone, Antje Janosch, Kenjiro Adachi, Martin Stehling, Eric N. Anderson, Masin Abo-Rady, Marc Bickle, Udai Bhan Pandey, Michell M. Reimer, Caghan Kizil, Hans R. Schöler, Peter Nussbaumer, Bert Klebl, Jared L. Sterneckert. Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo. Stem Cell Reports. 2019 Mar 04; 12:502-517. doi: 10.1016/j.stemcr.2019.01.015
Laura Kuehlewein, Ludger Schöls, Pablo Llavona, Alexander Grimm, Saskia Biskup, Eberhart Zrenner, Susanne Kohl. Phenotypic spectrum of autosomal recessive retinitis pigmentosa without posterior column ataxia caused by mutations in the FLVCR1 gene. Graefe's Archive for Clinical and Experimental Ophthalmology. 2019 Mar 03; 257:629-638. doi: 10.1007/s00417-018-04233-7
Oliver Kaut, Klaus Kuchelmeister, Christoph Moehl, Ullrich Wüllner. 5-methylcytosine and 5-hydroxymethylcytosine in brains of patients with multiple system atrophy and patients with Parkinson's disease. Journal of Chemical Neuroanatomy. 2019 Feb 28; 96:41-48. doi: 10.1016/j.jchemneu.2018.12.005
Marija Rankovic, Markus Zweckstetter. Upregulated levels and pathological aggregation of abnormally phosphorylated Tau-protein in children with neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews. 2019 Feb 28; 98:1-9. doi: 10.1016/j.neubiorev.2018.12.014
Benjamin Roeben, Dominik Blum, Heinz Gabriel, Matthis Synofzik. Atypical parkinsonism with severely reduced striatal dopamine uptake associated with a 16p11.2 duplication syndrome. Journal of Neurology. 2019 Feb 28; 266:775-776. doi: 10.1007/s00415-019-09182-7
Johannes Weickenmeier, Mathias Jucker, Alain Goriely, Ellen Kuhl. A physics-based model explains the prion-like features of neurodegeneration in Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Journal of the Mechanics and Physics of Solids. 2019 Feb 28; 124:264-281. doi: 10.1016/j.jmps.2018.10.013
Marta Bovet-Carmona, Karla Krautwald, Aurélie Menigoz, Rudi Vennekens, Detlef Balschun, Frank Angenstein. Low frequency pulse stimulation of Schaffer collaterals in Trpm4−/− knockout rats differently affects baseline BOLD signals in target regions of the right hippocampus but not BOLD responses at the site of stimulation. NeuroImage. 2019 Feb 28; 188:347-356. doi: 10.1016/j.neuroimage.2018.12.020
Theurey, P., N. M. C. Connolly, I. Fortunati, E. Basso, S. Lauwen, C. Ferrante, C. Moreira Pinho, A. Joselin, A. Gioran, D. Bano, D. S. Park, M. Ankarcrona, P. Pizzo and J. H. M. Prehn. Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons. Aging Cell. 2019 Feb 21; doi: 10.1111/acel.12924
Matthis Synofzik, Hélène Puccio, Fanny Mochel, Ludger Schöls. Autosomal Recessive Cerebellar Ataxias: Paving the Way toward Targeted Molecular Therapies. Neuron. 2019 Feb 19; 101:560-583. doi: 10.1016/j.neuron.2019.01.049
Maarten E. Witte, Adrian-Minh Schumacher, Christoph F. Mahler, Jan P. Bewersdorf, Jonas Lehmitz, Alexander Scheiter, Paula Sánchez, Philip R. Williams, Oliver Griesbeck, Ronald Naumann, Thomas Misgeld, Martin Kerschensteiner. Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis. Neuron. 2019 Feb 19; 101:615-624.e5. doi: 10.1016/j.neuron.2018.12.023
Frank Arne Wollenweber, Christian Opherk, Marialuisa Zedde, Cihan Catak, Rainer Malik, Marco Duering, Marek Janusz Konieczny, Rosario Pascarella, Raquel Samões, Manuel Correia, Joan Martí-Fàbregas, Jennifer Linn, Martin Dichgans. Prognostic relevance of cortical superficial siderosis in cerebral amyloid angiopathy. Neurology. 2019 Feb 18; 92:e792-e801. doi: 10.1212/WNL.0000000000006956
Matthew Traylor, Daniel J. Tozer, Iain D. Croall, Danuta M. Lisiecka Ford, Abiodun Olubunmi Olorunda, Giorgio Boncoraglio, Martin Dichgans, Robin Lemmens, Jonathan Rosand, Natalia S. Rost, Peter M. Rothwell, Cathie L M Sudlow, Vincent Thijs, Loes Rutten-Jacobs, Hugh S. Markus. Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226). Neurology. 2019 Feb 18; 92:e749-e757. doi: 10.1212/WNL.0000000000006952
Judith Houtman, Kiara Freitag, Niclas Gimber, Jan Schmoranzer, Frank L Heppner, Marina Jendrach. Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. EMBO Journal. 2019 Feb 14; 38 doi: 10.15252/embj.201899430
Stefan F. Lichtenthaler, Gökhan Güner. Pathology-linked protease caught in action. Science. 2019 Feb 14; 363:690-691. doi: 10.1126/science.aaw5547

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