Monoklonale Antikörper
Dr. Regina Feederle
Gruppenleiterin
c/o Helmholtz Zentrum München
Monoclonal Antibody Core Facility
Building 35.33
Ingolstädter Landstr. 1
85764 Neuherberg

regina.feederle@helmholtz-muenchen.de
 +49 89 3187-1360

Publications

Die vollständige Publikationsliste findet man hier.

Alkmini A Papadopoulou, Stephan A Müller, Torben Mentrup, Merav D Shmueli, Johannes Niemeyer, Martina Haug-Kröper, Julia von Blume, Artur Mayerhofer, Regina Feederle, Bernd Schröder, Stefan F Lichtenthaler, Regina Fluhrer. Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins. EMBO Reports. 2018 Dec 31; doi: 10.15252/embr.201846451
Petra Frick, Chantal Sellier, Ian R A Mackenzie, Chieh-Yu Cheng, Julie Tahraoui-Bories, Cecile Martinat, R Jeroen Pasterkamp, Johannes Prudlo, Dieter Edbauer, Mustapha Oulad-Abdelghani, Regina Feederle, Nicolas Charlet-Berguerand, Manuela Neumann. Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers. Acta neuropathologica communications. 2018 Aug 02; 6:72. doi: 10.1186/s40478-018-0579-0
Julia Herber, Jasenka Njavro, Regina Feederle, Ute Schepers, Ulrike C. Müller, Stefan Bräse, Stephan A. Müller, Stefan F. Lichtenthaler. Click chemistry-mediated biotinylation reveals a function for the protease BACE1 in modulating the neuronal surface glycoproteome. Molecular and Cellular Proteomics. 2018 Jul 31; 17:1487-1501. doi: 10.1074/mcp.RA118.000608
Alessio Colombo, Hung-En Hsia, Mengzhe Wang, Peer-Hendrik Kuhn, Monika S Brill, Paolo Canevazzi, Regina Feederle, Carla Taveggia, Thomas Misgeld, Stefan F Lichtenthaler. Non-cell-autonomous function of DR6 in Schwann cell proliferation. EMBO Journal. 2018 Apr 02; 37 doi: 10.15252/embj.201797390
Kai Schlepckow, Gernot Kleinberger, Akio Fukumori, Regina Feederle, Stefan F Lichtenthaler, Harald Steiner, Christian Haass. An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function. EMBO Molecular Medicine. 2017 Sep 30; 9:1356-1365. doi: 10.15252/emmm.201707672
Gernot Kleinberger, Matthias Brendel, Eva Mracsko, Benedikt Wefers, Linda Groeneweg, Xianyuan Xiang, Carola Focke, Maximilian Deußing, Marc Suárez-Calvet, Fargol Mazaheri, Samira Parhizkar, Nadine Pettkus, Wolfgang Wurst, Regina Feederle, Peter Bartenstein, Thomas Mueggler, Thomas Arzberger, Irene Knuesel, Axel Rominger, Christian Haass. The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism. EMBO Journal. 2017 Jul 02; 36:1837-1853. doi: 10.15252/embj.201796516
Carina Lehmer, Patrick Oeckl, Jochen H Weishaupt, Alexander E Volk, Janine Diehl-Schmid, Matthias L Schroeter, Martin Lauer, Johannes Kornhuber, Johannes Levin, Klaus Fassbender, Bernhard Landwehrmeyer, Martin H Schludi, Thomas Arzberger, Elisabeth Kremmer, Andrew Flatley, Regina Feederle, Petra Steinacker, Patrick Weydt, Albert C Ludolph, Dieter Edbauer, Markus Otto, Adrian Danek, Emily Feneberg, Sarah Anderl-Straub, Christine von Arnim, Holger Jahn, Anja Schneider, Manuel Maler, Maryna Polyakova, Lina Riedl, Jens Wiltfang, Georg Ziegler. Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD. EMBO Molecular Medicine. 2017 Jun 30; 9:859-868. doi: 10.15252/emmm.201607486
Qihui Zhou, Carina Lehmer, Meike Michaelsen, Kohji Mori, Dominik Alterauge, Dirk Baumjohann, Martin H. Schludi, Johanna Greiling, Daniel Farny, Andrew Flatley, Regina Feederle, Stephanie May, Franziska Schreiber, Thomas Arzberger, Christoph Kuhm, Thomas Klopstock, Andreas Hermann, Christian Haass, Dieter Edbauer. Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. EMBO Molecular Medicine. 2017 Apr 30; 9:687-702. doi: 10.15252/emmm.201607054
Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LDB, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, Müller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. eta-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015 Oct 15; 526:443-7. doi: 10.1038/nature14864

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