Publikationen


Xiaochen Hu, Charlotte E. Teunissen, Annika Spottke, Michael T. Heneka, Emrah Düzel, Oliver Peters, Siyao Li, Josef Priller, Katharina Buerger, Stefan Teipel, Christoph Laske, Sander C.J. Verfaillie, Frederik Barkhof, Nina Coll-Padrós, Lorena Rami, Jose Luis Molinuevo, Wiesje M. van der Flier, Frank Jessen. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease—Data from three memory clinic studies. Alzheimer's and Dementia. 2019 Jan 31; 15:185-193. doi: 10.1016/j.jalz.2018.09.002
Tina Heiland, Ulrike Zeitschel, Maja A. Puchades, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Jan G. Bjaalie, Maike Hartlage-Rübsamen, Steffen Roßner, Corinna Höfling. Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain. GLIA. 2019 Jan 31; 67:393-403. doi: 10.1002/glia.23550
René Günther, Christoph Neuwirth, Jan Christoph Koch, Paul Lingor, Nathalie Braun, Robert Untucht, Daniel Petzold, Markus Weber, Andreas Hermann. Motor Unit Number Index (MUNIX) of hand muscles is a disease biomarker for adult spinal muscular atrophy. Clinical Neurophysiology. 2019 Jan 31; 130:315-319. doi: 10.1016/j.clinph.2018.11.009
Sonja Schönecker, Franz Hell, Kai Bötzel, Elisabeth Wlasich, Nibal Ackl, Christine Süßmair, Markus Otto, Sarah Anderl-Straub, Albert Ludolph, Jan Kassubek, Hans-Jürgen Huppertz, Janine Diehl-Schmid, Lina Riedl, Carola Roßmeier, Klaus Fassbender, Epameinondas Lyros, Johannes Kornhuber, Timo Jan Oberstein, Klaus Fliessbach, Anja Schneider, Matthias L. Schroeter, Johannes Prudlo, Martin Lauer, Holger Jahn, Johannes Levin, Adrian Danek. The applause sign in frontotemporal lobar degeneration and related conditions. Journal of Neurology. 2019 Jan 31; 266:330-338. doi: 10.1007/s00415-018-9134-y
Fatemah A. Sakr, Michel J. Grothe, Enrica Cavedo, Irina Jelistratova, Marie-Odile Habert, Martin Dyrba, Gabriel Gonzalez-Escamilla, Hugo Bertin, Maxime Locatelli, Stephane Lehericy, Stefan Teipel, Bruno Dubois, Harald Hampel. Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: The INSIGHT-preAD study. Alzheimer's Research and Therapy. 2019 Jan 30; 11 doi: 10.1186/s13195-019-0466-3
Scherr M, Utz L, Tahmasian M, Pasquini L, Grothe MJ, Rauschecker JP, Grimmer T, Drzezga A, Sorg C, Riedl V. Effective connectivity in the default mode network is distinctively disrupted in Alzheimer's disease-A simultaneous resting-state FDG-PET/fMRI study. Hum Brain Mapp. 2019 Jan 30; doi: 10.1002/hbm.24517
María-Jesús Sobrido, Peter Bauer, Tom De Koning, Thomas Klopstock, Yann Nadjar, Marc C Patterson, Matthis Synofzik, Chris J Hendriksz. Recommendations for patient screening in ultra-rare inherited metabolic diseases: What have we learned from Niemann-Pick disease type C?. Orphanet journal of rare diseases. 2019 Jan 20; 14 doi: 10.1186/s13023-018-0985-1
Toda T, Parylak SL, Linker SB, Gage FH. The role of adult hippocampal neurogenesis in brain health and disease. Mol Psychiatry. 2019 Jan 20; 24:67-87. doi: 10.1038/s41380-018-0036-2
Georgakis MK, Gill D, Rannikmäe K, Traylor M, Anderson CD, MEGASTROKE consortium of the International Stroke Genetics Consortium, Lee JM, Kamatani Y, Hopewell JC, Worrall BB, Bernhagen J, Sudlow CLM, Malik R, Dichgans M. Genetically Determined Levels of Circulating Cytokines and Risk of Stroke: Role of Monocyte Chemoattractant Protein-1. Circulation. 2019 Jan 18; 139:256-268. doi: 10.1161/CIRCULATIONAHA.118.035905
Wolfsgruber S., Molinuevo JL, Wagner M, van der Flier WM, Jessen F, Euro-SCD working group. Prevalence of abnormal Alzheimer’s disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimers Res Ther. 2019 Jan 17; 11:8. doi: 10.1186/s13195-018-0463-y
Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, et al. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: Cross-sectional comparison of three European memory clinic samples Jose Luis Molinuevo, Frank Jessen and Wiesje Van der Flier. Alzheimer's Research and Therapy. 2019 Jan 16; 11 doi: 10.1186/s13195-018-0463-y
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Schilling S, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Beekman M, Deelen J, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, et al. Genetic and Lifestyle Risk Factors for MRI-Defined Brain Infarcts in a Population-Based Setting. Neurology. 2019 Jan 16; 92:486–503. doi: 10.1212/WNL.0000000000006851
Gras V, Pracht E, Mauconduit F, Le Bihan D, Stöcker T, Boulant N. Robust non-adiabatic T2-preparation using universal parallel-transmit kT-point pulses for 3D FLAIR imaging at 7 Tesla. Magnetic Resonance in Medicine. 2019 Jan 16; 81:3202-3208. doi: 10.1002/mrm.27645
Daniela Holle, Rene Müller-Widmer, Sven Reuther, Ute Rosier-Segschneider, Rabea Graf, Martina Roes, Margareta Halek. Process evaluation of the context, reach and recruitment of participants and delivery of dementia-specific case conferences (WELCOME-IdA) in nursing homes (FallDem): A mixed-methods study. Trials. 2019 Jan 13; 20 doi: 10.1186/s13063-018-3147-9
Weishäupl D, Schneider J, Peixoto Pinheiro B, Ruess C, Dold SM, von Zweydorf F, Gloeckner CJ, Schmidt J, Riess O, Schmidt T. Physiological and pathophysiological characteristics of ataxin-3 isoforms. J Biol Chem. 2019 Jan 11; 294:644-661. doi: 10.1074/jbc.RA118.005801
Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Kai Schlepckow, Miguel Ángel Araque Caballero, Nicolai Franzmeier, Anja Capell, Katrin Fellerer, Brigitte Nuscher, Erden Eren, Johannes Levin, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Leslie M. Shaw, John Q. Trojanowski, Michael Weiner, Michael Ewers, Christian Haass. Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology. Molecular Neurodegeneration. 2019 Jan 09; 14 doi: 10.1186/s13024-018-0301-5
Philipp Gunz, Amanda K. Tilot, Katharina Wittfeld, Alexander Teumer, Chin Yang Shapland, Theo G.M. van Erp, Michael Dannemann, Benjamin Vernot, Simon Neubauer, Tulio Guadalupe, Guillén Fernández, Han G. Brunner, Wolfgang Enard, James Fallon, Norbert Hosten, Uwe Völker, Antonio Profico, Fabio Di Vincenzo, Giorgio Manzi, Janet Kelso, Beate St. Pourcain, Jean-Jacques Hublin, Barbara Franke, Svante Pääbo, Fabio Macciardi, Hans J. Grabe, Simon E. Fisher. Neandertal Introgression Sheds Light on Modern Human Endocranial Globularity. Current Biology. 2019 Jan 06; 29:120-127.e5. doi: 10.1016/j.cub.2018.10.065
Canan Beate Schüller, Jens Kuhn, Frank Jessen, Xiaochen Hu. Neuronal correlates of delay discounting in healthy subjects and its implication for addiction: an ALE meta-analysis study. American Journal of Drug and Alcohol Abuse. 2019 Jan 01; 45:51-66. doi: 10.1080/00952990.2018.1557675
Wirth M, Schwarz C, Benson G, Horn N, Buchert R, Lange C, Kobe T, Hetzer S, Maglione M, Michael E, Marschenz S, Mai K, Kopp U, Schmitz D, Grittner U, Sigrist SJ, Stekovic S, Madeo F, Floel A. Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial. Alzheimer's research & therapy. 2019 Jan 01; 11:36. doi: 10.1186/s13195-019-0484-1
Ewers M, Franzmeier N, Suarez-Calvet M, Morenas-Rodriguez E, Araque Caballero MA, Kleineberger G, Piccio L, Cruchaga C, Robles Y, Dichgans M, Trojanowski JQ, Shaw LM, Weiner MW, Haass C for the Alzheimers Disease Neuroimaging Initiative. Increased soluble TREM2 is associated with reduced cognitive and clinical decline in Alzheimer’s disease. Sci Transl Med. 2019 Jan 01; in press
Cosacak MI, Bhattarai P, Reinhardt S, Petzold A, Dahl A, Zhang Y, et al. Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity. Cell Rep. 2019 Jan 01; 27:1307-18 e3. doi: 10.1016/j.celrep.2019.03.090
Celikkaya H, Cosacak MI, Papadimitriou C, Popova S, Bhattarai P, Biswas SN, et al. GATA3 Promotes the Neural Progenitor State but Not Neurogenesis in 3D Traumatic Injury Model of Primary Human Cortical Astrocytes. Front Cell Neurosci. 2019 Jan 01; 13:23. doi: 10.3389/fncel.2019.00023
Verdugo CD, Myren-Svelstad S, Aydin E, van Hoeymissen E, Deneubourg C, Vanderhaeghe S, et al. Glia-neuron interactions underlie state transitions to generalized seizures. Nat Commun. 2019 Jan 01; in press
Varvel NH, Ransohoff RM, Neher JJ. Functional Analysis of Brain-engrafted Monocytes after Microglial Ablation in Mouse Models. Methods in Molecular Biology. 2019 Jan 01; 2034:293-301. doi: 10.1007/978-1-4939-9658-2_22
Skodras AA, Hefendehl J, Neher JJ. Long-term in vivo imaging of individual microglia cells. Methods in Molecular Biology. 2019 Jan 01; 2034:177-189. doi: 10.1007/978-1-4939-9658-2_13
Krabbe S*, Paradiso E*, d’Aquin S, Bitterman Y, Courtin J, Xu C et al. (*co-first authors). Adaptive disinhibitory gating by VIP interneurons permits associative learning. Nature Neuroscience. 2019 Jan 01; 22:1834-1843. doi: 10.1038/s41593-019-0508-y
Gründemann J*, Bitterman Y*, Lu T, Krabbe S, Grewe BF, Schnitzer M et al. (*co-first authors). Amygdala ensembles encode behavioral states. Science. 2019 Jan 01; 364:pii:eaav8736. doi: 10.1126/science.aav8736
Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, et al. Dual Inhibition of GSK3beta and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo. Stem cell reports. 2019 Jan 01; doi: 10.1016/j.stemcr.2019.01.015
Sun W, Suzuki K, Toptunov D, Stoyanov S, Yuzaki M, Khiroug L, Dityatev A. In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed Motility in Mouse Cortex. Front Neurosci. 2019 Jan 01; 13:421. doi: 10.3389/fnins.2019.00421
Gaurav J*, Stuendl A*, Rao P, Berulava T, Centeno TP, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A#, Fischer A#. # equal contribution. A combined miRNA-piRNA signature to detect Alzheimer’s Disease. Transl. Psychiatry. 2019 Jan 01; 9:250. doi: 10.1038/s41398-019-0579-2

Info-Hotline

Donnerstags 13.30-16.30 Uhr

Für Patienten 0800-7799001

(kostenlos)

Für Ärzte 01803-779900

(9 Cent/Min. dt. Festnetz, mobil evtl. teurer)

Willkommen auf unserer Webseite, informieren Sie sich hier grundsätzlich cookie-frei.

Wir würden uns freuen, wenn Sie für die Optimierung unseres Informationsangebots ein Cookie zu Analysezwecken zulassen. Alle Daten sind pseudonym und werden nur durch das DZNE verwendet. Wir verzichten bewusst auf Drittanbieter-Cookies. Diese Einstellung können Sie jederzeit hier ändern.

Ihr Browser erlaubt das Setzen von Cookies: