Publikationen


Gupta VK, Pech U, Bhukel A, Fulterer A, Ender A, Mauermann SF, Andlauer TF, Antwi-Adjei E, Beuschel C, Thriene K, Maglione M, Quentin C, Bushow R, Schwärzel M, Mielke T, Madeo F, Dengjel J, Fiala A, Sigrist SJ. Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release. PLoS Biol. 2016 Sep 29; 14:e1002563. doi: 10.1371/journal.pbio.1002563
Varvel NH, Neher JJ, Bosch A, Wang W, Ransohoff RM, Miller RJ, Dingledine R. Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus. Proc Natl Acad Sci U S A. 2016 Sep 20; 113:E5665-74. doi: 10.1073/pnas.1604263113
Schuette V, Embgenbroich M, Ulas T, Welz M, Schulte-Schrepping J, Draffehn AM, Quast T, Koch K, Nehring M, König J, Zweynert A, Harms FL, Steiner N, Limmer A, Förster I, Berberich-Siebelt F, Knolle PA, Wohlleber D, Kolanus W, Beyer M, Schultze JL, Burgdorf S. Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4. Proc Natl Acad Sci U S A. 2016 Sep 20; 113:10649-54. doi: 10.1073/pnas.1605885113
Rodolfo Briones, Conrad Weichbrodt, Licia Paltrinieri, Ingo Mey, Saskia Villinger, Karin Giller, Adam Lange, Markus Zweckstetter, Christian Griesinger, Stefan Becker, Claudia Steinem, Bert L. de Groot. Voltage Dependence of Conformational Dynamics and Subconducting States of VDAC-1. Biophysical Journal. 2016 Sep 19; 111:1223-1234. doi: 10.1016/j.bpj.2016.08.007
Benita Wolf, Kathrin Krieg, Christine Falk, Kai Breuhahn, Hildegard Keppeler, Tilo Biedermann, Evi Schmid, Steven Warmann, Joerg Fuchs, Silvia Vetter, Dennis Thiele, Maike Nieser, Meltem Avci-Adali, Yulia Skokowa, Ludger Schöls, Stefan Hauser, Marc Ringelhan, Tetyana Yevsa, Mathias Heikenwalder, Uta Kossatz-Boehlert. Inducing differentiation of premalignant hepatic cells as a novel therapeutic strategy in hepatocarcinoma. Cancer Research. 2016 Sep 14; 76:5550-5561. doi: 10.1158/0008-5472.CAN-15-3453
Stefanou, Komorowski, Kade, Bornemann, Ziemann, Synofzik. A case of late-onset, thymoma-associated myasthenia gravis with ryanodine receptor and titin antibodies and concomitant granulomatous myositis. BMC Neurology. 2016 Sep 12; 16 doi: 10.1186/s12883-016-0697-x
Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C*, Geissmann F. Differentiation and specification of tissue-resident macrophages. Science. 2016 Sep 09; 353:6304. doi: 10.1126/science.aaf4238
Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome‐Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez‐Perdiguero E, Schultze JL, Beyer M*, Bock C*, Geissmann F*. Specification of tissue‐resident macrophages during organogenesis. Science. 2016 Sep 09; 353:pii: aaf4238.
Niklas Bode, Alena Grebe, Anja Kerksiek, Dieter Lütjohann, Nikos Werner, Georg Nickenig, Eicke Latz, Sebastian Zimmer. Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice. Biochemical and Biophysical Research Communications. 2016 Sep 08; 478:356-362. doi: 10.1016/j.bbrc.2016.07.047
Peter Engerer, Caroline Fecher, Thomas Misgeld. Super-resolution microscopy writ large. Nature Biotechnology. 2016 Sep 07; 34:928-930. doi: 10.1038/nbt.3669
Prudlo J, Konig J, Schuster C, Kasper E, Buttner A, Teipel S, Neumann M. TDP-43 pathology and cognition in ALS: A prospective clinicopathologic correlation study. Neurology. 2016 Sep 06; 87:1019-1023. doi: 10.1212/WNL.0000000000003062
Martin Klietz, Ursula Keber, Thomas Carlsson, Wei-Hua Chiu, Günter U. Höglinger, Eberhard Weihe, Martin K.-H. Schäfer, Candan Depboylu. L-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons. Neuroscience. 2016 Sep 06; 331:120-133. doi: 10.1016/j.neuroscience.2016.06.017
Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F. Specification of tissue-resident macrophages during organogenesis. Science. 2016 Sep 06; 353:pii: aaf4238. doi: 10.1126/science.aaf4238
Johannes Prudlo, Jochem König, Christina Schuster, Elisabeth Kasper, Andreas Büttner, Stefan Teipel, Manuela Neumann. TDP-43 pathology and cognition in ALS. Neurology. 2016 Sep 05; 87:1019-1023. doi: 10.1212/WNL.0000000000003062
Willy Gomm, Klaus Von Holt, Friederike Thomé, Karl Broich, Wolfgang Maier, Klaus Weckbecker, Anne Fink, Gabriele Doblhammer, Britta Haenisch. Regular Benzodiazepine and Z-Substance Use and Risk of Dementia: An Analysis of German Claims Data. Journal of Alzheimer's Disease. 2016 Sep 05; 54:801-808. doi: 10.3233/JAD-151006
Arons MH, Lee K, Thynne CJ, Kim SA, Schob C, Kindler S, Montgomery JM, Garner CC. Shank3 Is Part of a Zinc-Sensitive Signaling System That Regulates Excitatory Synaptic Strength. J Neurosci. 2016 Aug 31; 36:9124-34. doi: 10.1523/JNEUROSCI.0116-16.2016
Stefan Hauser, Stefanie Schuster, Yvonne Theurer, Matthis Synofzik, Ludger Schöls. Generation of optic atrophy 1 patient-derived induced pluripotent stem cells (iPS-OPA1-BEHR) for disease modeling of complex optic atrophy syndromes (Behr syndrome). Stem Cell Research. 2016 Aug 31; 17:426-429. doi: 10.1016/j.scr.2016.09.012
Philip Höflinger, Stefan Hauser, Yvonne Theurer, Stefanie Weißenberger, Carlo Wilke, Ludger Schöls. Induced pluripotent stem cells (iPSCs) derived from cerebrotendinous xanthomatosis (CTX) patient's fibroblasts carrying a R395S mutation. Stem Cell Research. 2016 Aug 31; 17:433-436. doi: 10.1016/j.scr.2016.09.010
Matthew J. Betts, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Peter J. Nestor, Emrah Düzel. High-resolution characterisation of the aging brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 T. NeuroImage. 2016 Aug 31; 138:43-63. doi: 10.1016/j.neuroimage.2016.05.024
Stefan Hauser, Philip Höflinger, Yvonne Theurer, Tim W Rattay, Ludger Schöls. Generation of induced pluripotent stem cells (iPSCs) from a hereditary spastic paraplegia patient carrying a homozygous Y275X mutation in CYP7B1 (SPG5). Stem Cell Research. 2016 Aug 31; 17:437-440. doi: 10.1016/j.scr.2016.09.011
Philip Höflinger, Yvonne Theurer, Rebecca Schüle, Ludger Schöls, Stefan Hauser. Generation of induced pluripotent stem cells (iPSCs) from a hereditary spastic paraplegia patient carrying a homozygous R486C mutation in CYP7B1 (SPG5). Stem Cell Research. 2016 Aug 31; 17:422-425. doi: 10.1016/j.scr.2016.09.013
Joel A. Schick, Claudia Seisenberger, Joachim Beig, Antje Bürger, Vivek Iyer, Viola Maier, Sajith Perera, Barry Rosen, William C. Skarnes, Wolfgang Wurst. CRISPR-Cas9 enables conditional mutagenesis of challenging loci. Scientific Reports. 2016 Aug 31; 6 doi: 10.1038/srep32326
Jochen Klenk, Karin Srulijes, Cornelia Schatton, Lars Schwickert, Walter Maetzler, Clemens Becker, Matthis Synofzik. Ambulatory activity components deteriorate differently across neurodegenerative diseases: A cross-sectional sensor-based study. Neurodegenerative Diseases. 2016 Aug 31; 16:317-323. doi: 10.1159/000444802
Kohji Mori, Yoshihiro Nihei, Thomas Arzberger, Qihui Zhou, Ian R Mackenzie, Andreas Hermann, Frank Hanisch, Frits Kamp, Brigitte Nuscher, Denise Orozco, Dieter Edbauer, Christian Haass. Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition. EMBO Reports. 2016 Aug 31; 17:1314-1325. doi: 10.15252/embr.201541724
Xianyuan Xiang, Georg Werner, Bernd Bohrmann, Arthur Liesz, Fargol Mazaheri, Anja Capell, Regina Feederle, Irene Knuesel, Gernot Kleinberger, Christian Haass. TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance. EMBO Molecular Medicine. 2016 Aug 31; 8:992-1004. doi: 10.15252/emmm.201606370
Gamze Guven, Ebba Lohmann, Jose Bras, J. Raphael Gibbs, Hakan Gurvit, Basar Bilgic, Hasmet Hanagasi, Patrizia Rizzu, Peter Heutink, Murat Emre, Nihan Erginel-Unaltuna, Walter Just, John Hardy, Andrew Singleton, Rita Guerreiro. Mutation frequency of the major frontotemporal dementia genes, MAPT, GRN and C9ORF72 in a Turkish cohort of dementia patients. PLoS ONE. 2016 Aug 31; 11 doi: 10.1371/journal.pone.0162592
Tobias B. Haack, Arcangela Iuso, Laura S. Kremer, Monika Hartig, Tim M. Strom, Thomas Meitinger, Holger Prokisch, Tobias B. Haack, Arcangela Iuso, Matteo Gorza, Laura S. Kremer, Elisabeth Graf, Riccardo Berutti, Tim M. Strom, Thomas Meitinger, Holger Prokisch, Erika Ignatius, Pirjo Isohanni, Anu Suomalainen, Christopher J. Carroll, Erika Ignatius, Pirjo Isohanni, Tuula Lönnqvist, Javier Calvo-Garrido, Henrik Stranneheim, Anna Wedell, Camilla Maffezzini, Christoph Freyer, Anna Wredenberg, Martin Paucar, Per Svenningsson, Henrik Stranneheim, Anna Wedell, Christoph Freyer, Anna Wredenberg, Göran Brandberg, Manju A. Kurian, Manju A. Kurian, Susan A. Hayflick, Susan A. Hayflick, Susan A. Hayflick, Paola Venco, Valeria Tiranti, Martin Dichgans, Martin Dichgans, Thomas Meitinger, Thomas Klopstock, Martin Dichgans, Thomas Klopstock, Rita Horvath, Elke Holinski-Feder, Jan Senderek, Thomas Klopstock. Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy. American Journal of Human Genetics. 2016 Aug 31; 99:735-743. doi: 10.1016/j.ajhg.2016.06.026
Patrick Müller, Kathrin Rehfeld, Angie Lüders, Marlen Schmicker, Anita Hökelmann, Jörn Kaufman, Notger G. Müller. Effect of dancing and exercise training on the grey matter in the brain of healthy seniors. Sportwissenschaft. 2016 Aug 31; 46:213-222. doi: 10.1007/s12662-016-0411-6
Kariminejad, Schöls, Schüle, Tonekaboni, Abolhassani, Fadaee, Rosti, Gleeson. CYP2U1 mutations in two Iranian patients with activity induced dystonia, motor regression and spastic paraplegia. European Journal of Paediatric Neurology. 2016 Aug 31; 20:782-787. doi: 10.1016/j.ejpn.2016.05.013
Stefan J. Teipel, Enrica Cavedo, Michel J. Grothe, Simone Lista, Samantha Galluzzi, Olivier Colliot, Marie Chupin, Hovagim Bakardjian, Didier Dormont, Bruno Dubois, Harald Hampel. Predictors of cognitive decline and treatment response in a clinical trial on suspected prodromal Alzheimer's disease. Neuropharmacology. 2016 Aug 31; 108:128-135. doi: 10.1016/j.neuropharm.2016.02.005

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