Publikationen


Janine Diehl-Schmid, Abigail Licata, Oliver Goldhardt, Hans Förstl, Igor Yakushew, Markus Otto, Sarah Anderl-Straub, Ambros Beer, Albert Christian Ludolph, Georg Bernhard Landwehrmeyer, Johannes Levin, Adrian Danek, Klaus Fliessbach, Annika Spottke, Klaus Fassbender, Epameinondas Lyros, Johannes Prudlo, Bernd Joachim Krause, Alexander Volk, Dieter Edbauer, Matthias Leopold Schroeter, Alexander Drzezga, Johannes Kornhuber, Martin Lauer, Nibal Ackl, Christine v. Arnim, Joachim Brumberg, Florian Gärtner, Holger Jahn, Elisabeth Kasper, Jan Kassubek, Catharina Prix, Lina Riedl, Carola Roßmeier, Sonja Schönecker, Elisa Semler, Stefan Teipel, Christine Westerteicher, Elisabeth Wlasich, Timo Grimmer. FDG-PET underscores the key role of the thalamus in frontotemporal lobar degeneration caused by C9ORF72 mutations. Translational Psychiatry. 2019 Nov 30; 9 doi: 10.1038/s41398-019-0381-1
Maria Carolina Dalmasso, Luis Ignacio Brusco, Natividad Olivar, Carolina Muchnik, Claudia Hanses, Esther Milz, Julian Becker, Stefanie Heilmann-Heimbach, Per Hoffmann, Federico A. Prestia, Pablo Galeano, Mariana Soledad Sanchez Avalos, Luis Eduardo Martinez, Mariana Estela Carulla, Pablo Javier Azurmendi, Cynthia Liberczuk, Cristina Fezza, Marcelo Sampaño, Maria Fierens, Guillermo Jemar, Patricia Solis, Nancy Medel, Julieta Lisso, Zulma Sevillano, Paolo Bosco, Paola Bossù, Gianfranco Spalletta, Daniela Galimberti, Michelangelo Mancuso, Benedetta Nacmias, Sandro Sorbi, Patrizia Mecocci, Alberto Pilotto, Paolo Caffarra, Francesco Panza, Maria Bullido, Jordi Clarimon, Pascual Sánchez-Juan, Eliecer Coto, Florentino Sanchez-Garcia, Caroline Graff, Martin Ingelsson, Céline Bellenguez, Eduardo Miguel Castaño, Claudia Kairiyama, Daniel Gustavo Politis, Silvia Kochen, Horacio Scaro, Wolfgang Maier, Frank Jessen, Carlos Alberto Mangone, Jean-Charles Lambert, Laura Morelli, Alfredo Ramirez. Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease. Translational Psychiatry. 2019 Nov 30; 9 doi: 10.1038/s41398-019-0394-9
Jonathan Vöglein, Soheyl Noachtar, Eric McDade, Kimberly A. Quaid, Stephen Salloway, Bernardino Ghetti, James Noble, Sarah Berman, Jasmeer Chhatwal, Hiroshi Mori, Nick Fox, Ricardo Allegri, Colin L. Masters, Virginia Buckles, John M. Ringman, Martin Rossor, Peter R. Schofield, Reisa Sperling, Mathias Jucker, Christoph Laske, Katrina Paumier, John C. Morris, Randall J. Bateman, Johannes Levin, Adrian Danek. Seizures as an early symptom of autosomal dominant Alzheimer's disease. Neurobiology of Aging. 2019 Mar 31; 76:18-23. doi: 10.1016/j.neurobiolaging.2018.11.022
Marcus Pickhardt, Michele Tassoni, Philip Denner, Birgit Kurkowsky, Ana Kitanovic, Christoph Möhl, Eugenio Fava, Eckhard Mandelkow. Screening of a neuronal cell model of tau pathology for therapeutic compounds. Neurobiology of Aging. 2019 Mar 31; 76:24-34. doi: 10.1016/j.neurobiolaging.2018.11.026
Enrico Premi, Vince D. Calhoun, Matteo Diano, Stefano Gazzina, Maura Cosseddu, Antonella Alberici, Silvana Archetti, Donata Paternicò, Roberto Gasparotti, John van Swieten, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris Butler, Simon Ducharme, Alex Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Giovanni Frisoni, Stefano Cappa, Sandro Sorbi, Alessandro Padovani, Jonathan D. Rohrer, Barbara Borroni. The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint. NeuroImage. 2019 Mar 31; 189:645-654. doi: 10.1016/j.neuroimage.2019.01.080
Oliver Kaut, Klaus Kuchelmeister, Christoph Moehl, Ullrich Wüllner. 5-methylcytosine and 5-hydroxymethylcytosine in brains of patients with multiple system atrophy and patients with Parkinson's disease. Journal of Chemical Neuroanatomy. 2019 Feb 28; 96:41-48. doi: 10.1016/j.jchemneu.2018.12.005
Marija Rankovic, Markus Zweckstetter. Upregulated levels and pathological aggregation of abnormally phosphorylated Tau-protein in children with neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews. 2019 Feb 28; 98:1-9. doi: 10.1016/j.neubiorev.2018.12.014
Johannes Weickenmeier, Mathias Jucker, Alain Goriely, Ellen Kuhl. A physics-based model explains the prion-like features of neurodegeneration in Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Journal of the Mechanics and Physics of Solids. 2019 Feb 28; 124:264-281. doi: 10.1016/j.jmps.2018.10.013
Marta Bovet-Carmona, Karla Krautwald, Aurélie Menigoz, Rudi Vennekens, Detlef Balschun, Frank Angenstein. Low frequency pulse stimulation of Schaffer collaterals in Trpm4−/− knockout rats differently affects baseline BOLD signals in target regions of the right hippocampus but not BOLD responses at the site of stimulation. NeuroImage. 2019 Feb 28; 188:347-356. doi: 10.1016/j.neuroimage.2018.12.020
Hans-Christian J. Fritz, Nicola Ray, Martin Dyrba, Christian Sorg, Stefan Teipel, Michel J. Grothe. The corticotopic organization of the human basal forebrain as revealed by regionally selective functional connectivity profiles. Human Brain Mapping. 2019 Feb 14; 40:868-878. doi: 10.1002/hbm.24417
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Carola Focke, Brigitte Nuscher, Monica Xiong, Alireza Ghasemigharagoz, Natalie Katzmarski, Susanne Krasemann, Stefan F. Lichtenthaler, Stephan A. Müller, Alessio Colombo, Laura Sebastian Monasor, Sabina Tahirovic, Jochen Herms, Michael Willem, Nadine Pettkus, Oleg Butovsky, Peter Bartenstein, Dieter Edbauer, Axel Rominger, Ali Ertürk, Stefan A. Grathwohl, Jonas J. Neher, David M. Holtzman, Melanie Meyer-Luehmann, Christian Haass. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. 2019 Jan 31; 22:191-204. doi: 10.1038/s41593-018-0296-9
Oliver Preische, Stephanie A. Schultz, Anja Apel, Jens Kuhle, Stephan A. Kaeser, Christian Barro, Susanne Gräber, Elke Kuder-Buletta, Christian LaFougere, Christoph Laske, Jonathan Vöglein, Johannes Levin, Colin L. Masters, Ralph Martins, Peter R. Schofield, Martin N. Rossor, Neill R. Graff-Radford, Stephen Salloway, Bernardino Ghetti, John M. Ringman, James M. Noble, Jasmeer Chhatwal, Alison M. Goate, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Guoqiao Wang, Anne M. Fagan, Eric M. McDade, Brian A. Gordon, Mathias Jucker, Ricardo Allegri, Fatima Amtashar, Randall Bateman, Tammie Benzinger, Sarah Berman, Courtney Bodge, Susan Brandon, William Brooks, Jill Buck, Virginia Buckles, Sochenda Chea, Jasmeer Chhatwal, Patricio Chrem, Helena Chui, Jake Cinco, Jack Clifford, Carlos Cruchaga, Mirelle D’Mello, Tamara Donahue, Jane Douglas, Noelia Edigo, Nilufer Erekin-Taner, Anne Fagan, Marty Farlow, Angela Farrar, Howard Feldman, Gigi Flynn, Nick Fox, Erin Franklin, Hisako Fujii, Cortaiga Gant, Samantha Gardener, Bernardino Ghetti, Alison Goate, Jill Goldman, Brian Gordon, Neill Graff-Radford, Julia Gray, Jenny Gurney, Jason Hassenstab, Mie Hirohara, David Holtzman, Russ Hornbeck, Siri Houeland DiBari, Takeshi Ikeuchi, Snezana Ikonomovic, Gina Jerome, Mathias Jucker, Celeste Karch, Kensaku Kasuga, Takeshi Kawarabayashi, William Klunk, Robert Koeppe, Elke Kuder-Buletta, Christoph Laske, Jae-Hong Lee, Johannes Levin, Daniel Marcus, Ralph Martins, Neal Scott Mason, Colin Masters, Denise Maue-Dreyfus, Eric McDade, Lucy Montoya, Hiroshi Mori, John Morris, Akem Nagamatsu, Katie Neimeyer, James Noble, Joanne Norton, Richard Perrin, Marc Raichle, John Ringman, Jee Hoon Roh, Stephen Salloway, Peter Schofield, Hiroyuki Shimada, Tomoyo Shiroto, Mikio Shoji, Wendy Sigurdson, Hamid Sohrabi, Paige Sparks, Kazushi Suzuki, Laura Swisher, Kevin Taddei, Jen Wang, Peter Wang, Mike Weiner, Mary Wolfsberger, Chengjie Xiong, Xiong Xu. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease. Nature Medicine. 2019 Jan 31; 25:277-283. doi: 10.1038/s41591-018-0304-3
Nicole Reichenbach, Andrea Delekate, Monika Plescher, Franziska Schmitt, Sybille Krauss, Nelli Blank, Annett Halle, Gabor C Petzold. Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model. EMBO Molecular Medicine. 2019 Jan 31; 11 doi: 10.15252/emmm.201809665
Eirini Kanata, Ewa Golanska, Anna Villar-Piqué, Aikaterini Karsanidou, Dimitra Dafou, Konstantinos Xanthopoulos, Matthias Schmitz, Isidro Ferrer, André Karch, Beata Sikorska, Pawel P. Liberski, Theodoros Sklaviadis, Inga Zerr, Franc Llorens. Cerebrospinal fluid neurofilament light in suspected sporadic Creutzfeldt-Jakob disease. Journal of Clinical Neuroscience. 2019 Jan 31; 60:124-127. doi: 10.1016/j.jocn.2018.09.031
Jennifer Wojtala, Ines Ann Heber, Petra Neuser, Julia Heller, Elke Kalbe, Sarah P Rehberg, Alexander Storch, Katharina Linse, Christine Schneider, Susanne Gräber, Daniela Berg, Judith Dams, Monika Balzer-Geldsetzer, Rüdiger Hilker-Roggendorf, Carola Oberschmidt, Simon Baudrexel, Karsten Witt, Nele Schmidt, Günther Deuschl, Brit Mollenhauer, Claudia Trenkwalder, Inga Liepelt-Scarfone, Annika Spottke, Sandra Roeske, Ullrich Wüllner, Hans-Ulrich Wittchen, Oliver Riedel, Richard Dodel, Jörg B Schulz, Kathrin Reetz. Cognitive decline in Parkinson's disease: The impact of the motor phenotype on cognition. Journal of Neurology, Neurosurgery and Psychiatry. 2019 Jan 31; 90:171-179. doi: 10.1136/jnnp-2018-319008
Johannes M. Weller, Elke Hattingen, Gabor C. Petzold, Felix J Bode. Successful mechanical thrombectomy in stroke with thrombolysis-associated intracerebral hemorrhage—a case report. Journal of Stroke and Cerebrovascular Diseases. 2019 Jan 31; 28:285-287. doi: 10.1016/j.jstrokecerebrovasdis.2018.09.045
Kathy Y. Liu, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Clare Loane, Alex J. Berry, Matthew J. Betts, Rogier A. Kievit, Richard N. Henson, Emrah Düzel, Robert Howard, Dorothea Hämmerer. In vivo visualization of age-related differences in the locus coeruleus. Neurobiology of Aging. 2019 Jan 31; 74:101-111. doi: 10.1016/j.neurobiolaging.2018.10.014
Xiaochen Hu, Charlotte E. Teunissen, Annika Spottke, Michael T. Heneka, Emrah Düzel, Oliver Peters, Siyao Li, Josef Priller, Katharina Buerger, Stefan Teipel, Christoph Laske, Sander C.J. Verfaillie, Frederik Barkhof, Nina Coll-Padrós, Lorena Rami, Jose Luis Molinuevo, Wiesje M. van der Flier, Frank Jessen. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease—Data from three memory clinic studies. Alzheimer's and Dementia. 2019 Jan 31; 15:185-193. doi: 10.1016/j.jalz.2018.09.002
Tina Heiland, Ulrike Zeitschel, Maja A. Puchades, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Jan G. Bjaalie, Maike Hartlage-Rübsamen, Steffen Roßner, Corinna Höfling. Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain. GLIA. 2019 Jan 31; 67:393-403. doi: 10.1002/glia.23550
René Günther, Christoph Neuwirth, Jan Christoph Koch, Paul Lingor, Nathalie Braun, Robert Untucht, Daniel Petzold, Markus Weber, Andreas Hermann. Motor Unit Number Index (MUNIX) of hand muscles is a disease biomarker for adult spinal muscular atrophy. Clinical Neurophysiology. 2019 Jan 31; 130:315-319. doi: 10.1016/j.clinph.2018.11.009
Sonja Schönecker, Franz Hell, Kai Bötzel, Elisabeth Wlasich, Nibal Ackl, Christine Süßmair, Markus Otto, Sarah Anderl-Straub, Albert Ludolph, Jan Kassubek, Hans-Jürgen Huppertz, Janine Diehl-Schmid, Lina Riedl, Carola Roßmeier, Klaus Fassbender, Epameinondas Lyros, Johannes Kornhuber, Timo Jan Oberstein, Klaus Fliessbach, Anja Schneider, Matthias L. Schroeter, Johannes Prudlo, Martin Lauer, Holger Jahn, Johannes Levin, Adrian Danek. The applause sign in frontotemporal lobar degeneration and related conditions. Journal of Neurology. 2019 Jan 31; 266:330-338. doi: 10.1007/s00415-018-9134-y
Fatemah A. Sakr, Michel J. Grothe, Enrica Cavedo, Irina Jelistratova, Marie-Odile Habert, Martin Dyrba, Gabriel Gonzalez-Escamilla, Hugo Bertin, Maxime Locatelli, Stephane Lehericy, Stefan Teipel, Bruno Dubois, Harald Hampel. Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: The INSIGHT-preAD study. Alzheimer's Research and Therapy. 2019 Jan 30; 11 doi: 10.1186/s13195-019-0466-3
María-Jesús Sobrido, Peter Bauer, Tom de Koning, Thomas Klopstock, Yann Nadjar, Marc C. Patterson, Matthis Synofzik, Chris J. Hendriksz. Recommendations for patient screening in ultra-rare inherited metabolic diseases: what have we learned from Niemann-Pick disease type C?. Orphanet journal of rare diseases. 2019 Jan 20; 14:20. doi: 10.1186/s13023-018-0985-1
Toda T, Parylak SL, Linker SB, Gage FH. The role of adult hippocampal neurogenesis in brain health and disease. Mol Psychiatry. 2019 Jan 20; 24:67-87. doi: 10.1038/s41380-018-0036-2
Steffen Wolfsgruber, José Luis Molinuevo, Michael Wagner, Charlotte E. Teunissen, Lorena Rami, Nina Coll-Padrós, Femke H. Bouwman, Rosalinde E. R. Slot, Linda M. P. Wesselman, Oliver Peters, Katja Luther, Katharina Buerger, Josef Priller, Christoph Laske, Stefan Teipel, Annika Spottke, Michael T. Heneka, Emrah Düzel, Alexander Drzezga, Jens Wiltfang, Sietske A. M. Sikkes, Wiesje M. Van Der Flier, Frank Jessen. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: Cross-sectional comparison of three European memory clinic samples Jose Luis Molinuevo (jlmolinuevo@barcelonabeta.org); Frank Jessen (frank.jessen@uk-koeln.de); Wiesje Van der Flier (WM.vdFlier@vumc.nl). Alzheimer's Research and Therapy. 2019 Jan 16; 11 doi: 10.1186/s13195-018-0463-y
Daniela Holle, Rene Müller-Widmer, Sven Reuther, Ute Rosier-Segschneider, Rabea Graf, Martina Roes, Margareta Halek. Process evaluation of the context, reach and recruitment of participants and delivery of dementia-specific case conferences (WELCOME-IdA) in nursing homes (FallDem): A mixed-methods study. Trials. 2019 Jan 13; 20 doi: 10.1186/s13063-018-3147-9
Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Kai Schlepckow, Miguel Ángel Araque Caballero, Nicolai Franzmeier, Anja Capell, Katrin Fellerer, Brigitte Nuscher, Erden Eren, Johannes Levin, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Leslie M. Shaw, John Q. Trojanowski, Michael Weiner, Michael Ewers, Christian Haass. Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology. Molecular Neurodegeneration. 2019 Jan 09; 14 doi: 10.1186/s13024-018-0301-5
Philipp Gunz, Amanda K. Tilot, Katharina Wittfeld, Alexander Teumer, Chin Yang Shapland, Theo G.M. van Erp, Michael Dannemann, Benjamin Vernot, Simon Neubauer, Tulio Guadalupe, Guillén Fernández, Han G. Brunner, Wolfgang Enard, James Fallon, Norbert Hosten, Uwe Völker, Antonio Profico, Fabio Di Vincenzo, Giorgio Manzi, Janet Kelso, Beate St. Pourcain, Jean-Jacques Hublin, Barbara Franke, Svante Pääbo, Fabio Macciardi, Hans J. Grabe, Simon E. Fisher. Neandertal Introgression Sheds Light on Modern Human Endocranial Globularity. Current Biology. 2019 Jan 06; 29:120-127.e5. doi: 10.1016/j.cub.2018.10.065
Frank Dondelinger, Sach Mukherjee. Statistical Network Inference for Time-Varying Molecular Data with Dynamic Bayesian Networks. Methods in molecular biology (Clifton, N.J.). 2018 Dec 31; 1883:25-48. doi: 10.1007/978-1-4939-8882-2_2
Marc Aurel Busche, Susanne Wegmann, Simon Dujardin, Caitlin Commins, Julia Schiantarelli, Naomi Klickstein, Tarun V. Kamath, George A. Carlson, Israel Nelken, Bradley T. Hyman. Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo. Nature neuroscience. 2018 Dec 31; 22:57-64. doi: 10.1038/s41593-018-0289-8

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