Andreas Hermann
Translationale Neurodegeneration
Prof. Dr. Dr. Andreas Hermann
Gruppenleiter
Gehlsheimer Str. 20
18147  Rostock

andreas.hermann@dzne.de
 +49 381 494-9541

Publikationen

Die vollständige Publikationsübersicht findet man hier.

Naumann M, Peikert K, Günther K, van der Kooi AJ, Aronica E, Hübers A, Danel V, Corcia P, Pan-Montojo F, Cirak S, Haliloglu G, Ludolph AC, Goswami A, Andersen PM, Prudlo J, Wegner F, Van Damme P, Weishaupt JH, Hermann A. Phenotypes and malignancy risk of different FUS/TLS mutations in genetic ALS. Ann Clin Transl Neurol. 2019 Nov 04; doi: 10.1002/acn3.50930
Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H. Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C. Ludolph, Tobias M. Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony A. Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Nature Communications. 2018 Nov 30; 9 doi: 10.1038/s41467-017-02299-1
Arun Pal, Hannes Glaß, Marcel Naumann, Nicole Kreiter, Julia Japtok, Ronny Sczech, Andreas Hermann. High content organelle trafficking enables disease state profiling as powerful tool for disease modelling. Scientific data. 2017 Dec 31; 5 doi: 10.1038/sdata.2018.241
Kreiter, Pal, Lojewski, Corcia, Naujock, Reinhardt, Sterneckert, Petri, Wegner, Storch, Hermann. Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation. Neurobiology of Disease. 2018 Jun 30; 115:167-181. doi: 10.1016/j.nbd.2018.03.010
Linse K, Rüger W, Joos M, Schmitz-Peiffer H, Storch A, Hermann A. Eyetracking-based assessment suggests preserved wellbeing in locked-in patients. Ann Neurol. 2017 Jan 01; 81:310-315. doi: 10.1002/ana.24871
Julia Japtok, Xenia Lojewksi, Marcel Naumann, Moritz Klingenstein, Peter Reinhardt, Jared Sterneckert, Stefan Putz, Maria Demestre, Tobias M. Boeckers, Albert C. Ludolph, Stefan Liebau, Alexander Storch, Andreas Hermann. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging. Neurobiology of Disease. 2015 Sep 30; 82:420-429. doi: 10.1016/j.nbd.2015.07.017
Ludolph AC, Schuster J, Dorst J, Dupuis L, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Wollebæk Johannesen S, Göricke B; RAS-ALS Study Group. Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial. Lancet Neurol. 2018 Aug 01; 17:681-688. doi: 10.1016/S1474-4422(18)30176-5
Xenia Lojewski, John F. Staropoli, Sunita Biswas-legrand, Alexandra M. Simas, Larissa Haliw, Martin K. Selig, Scott H. Coppel, Kendrick A. Goss, Anton Petcherski, Uma Chandrachud, Steven D. Sheridan, Diane Lucente, Katherine B. Sims, James F. Gusella, Dolan Sondhi, Ronald G. Crystal, Peter Reinhardt, Jared Sterneckert, Hans Schöler, Stephen J. Haggarty, Alexander Storch, Andreas Hermann, Susan L. Cotman. Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway. Human Molecular Genetics. 2014 Mar 31; 23:2005-2022. doi: 10.1093/hmg/ddt596
Dong Wook Han, Natalia Tapia, Andreas Hermann, Kathrin Hemmer, Susanne Höing, Marcos J. Araúzo-Bravo, Holm Zaehres, Guangming Wu, Stefan Frank, Sören Moritz, Boris Greber, Ji Hun Yang, Hoon Taek Lee, Jens C. Schwamborn, Alexander Storch, Hans R. Schöler. Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell. 2012 Apr 05; 10:465-472. doi: 10.1016/j.stem.2012.02.021
Hermann A, Gastl R, Liebau S, Popa MO, Fiedler J, Boehm BO, et al. Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells. J Cell Sci. 2004 Sep 01; 117:4411-4422. doi: 10.1242/jcs.01307

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