CV: Anastasia Piyanova received a diploma in physiology from Moscow State University in 2008. She then joined the Institute of Molecular Psychiatry in Bonn (director: Professor A.Zimmer). In her studies, she focused on the role of endocannabinoid system in brain aging. She received a PhD degree (Dr. rer. nat.) from the University of Bonn in 2012. Since April 2012 she has been a postdoctoral researcher at the DZNE in Bonn, studying the role of microRNAs in synaptic plasticity.
MicroRNAs are small non-coding RNAs (20-22 nt long) that can bind to the 3’-UTR region of mRNAs, thereby inhibiting translation of proteins or inducing mRNA degradation by a mechanism similar to siRNA (silencing RNA). MiRNAs are crucial to many biological processes, such as cell differentiation and development. In the recent years, miRNAs have also been shown to play an important role in aging and neurodegenerative diseases. The aim of my study is to further understand the contribution of miRNAs in these pathological processes and elucidate the basic mechanisms by which miRNAs can control synaptic plasticity.