Molekulare Immunologie & Neurodegeneration
Priv.-Doz. Dr. Marc Beyer
Gruppenleiter
Sigmund-Freud-Str. 27
53127 Bonn

marc.beyer@dzne.de
 +49 228 43302-565

Publikationen

Die vollständige Publikationsliste findet man hier.

See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017 Jun 09; 356:pii: eaag3009.
Beyer M, Huehn J. Epigenetic orchestration of thymic Treg cell development. Nat Immunol. 2017 Jan 19; 18:144-146.
Tedeschi A, Dupraz S, Laskowski CJ, Xue J, Ulas T, Beyer M, Schultze JL, Bradke F. The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS. Neuron. 2016 Oct 19; 92:419-434. doi: 10.1016/j.neuron.2016.09.026
Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome‐Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez‐Perdiguero E, Schultze JL, Beyer M*, Bock C*, Geissmann F*. Specification of tissue‐resident macrophages during organogenesis. Science. 2016 Sep 09; 353:pii: aaf4238.
Schultze JL, Beyer M. Myelopoiesis reloaded: Single cell transcriptomics leads the way. Immunity. 2016 Jan 19; 44:18-22.
Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Shinde PV, Lehmann C, Thabet Y, Hofmann A, Popov A, Lang KS, Fätkenheuer G, Lang PA, Hartmann P, Knolle PA, Schultze JL. TNF dependent induction of inhibitory pathways in CD4+ T cells in advanced human HIV and murine LCMV infection. Nat Immunol. 2016 Mar 07; doi: 10.1038/ni.3399
Schmidt SV, Krebs W, Ulas T, Xue J, Baßler K, Günther P, Hardt A-L, Schultze H, Sander J, Klee K, Theis H, Kraut M, Beyer M, Schultze JL. The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin. Cell Res. 2016 Feb 01; 26:151-70.
Böttcher JP*, Beyer M*, Meissner F, Abdullah Z, Sander J, Höchst B, Eickhoff S, Rieckmann J, Rousso C, Bauer T, Dolf A, Endl E, Engel D, Jung S, Busch D, Protzer U, Thimme R, Mann M, Kurts C, Schultze JL, Kastenmüller W, Knolle PA. * shared first authors. CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles. Nat Commun. 2015 Sep 25; 6:8306.
Wolfgang Krebs, Susanne V. Schmidt, Alon Goren, Dominic De Nardo, Larisa Labzin, Anton Bovier, Thomas Ulas, Heidi Theis, Michael Kraut, Eicke Latz, Marc Beyer, Joachim L. Schultze. Optimization of transcription factor binding map accuracy utilizing knockout-mouse models. Nucleic Acids Research. 2014 Nov 30; 42:13051-13060. doi: 10.1093/nar/gku1078
Jia Xue, Susanne V. Schmidt, Jil Sander, Astrid Draffehn, Wolfgang Krebs, Inga Quester, Dominic DeNardo, Trupti D. Gohel, Martina Emde, Lisa Schmidleithner, Hariharasudan Ganesan, Andrea Nino-Castro, Michael R. Mallmann, Larisa Labzin, Heidi Theis, Michael Kraut, Marc Beyer, Eicke Latz, Tom C. Freeman, Thomas Ulas, Joachim L. Schultze. Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation. Immunity. 2014 Feb 19; 40:274-288. doi: 10.1016/j.immuni.2014.01.006
Sommer D, Peters A, Wirtz T, Mai M, Ackermann J, Thabet Y, Schmidt J, Weighardt H, Wunderlich FT, Degen J, Schultze JL, Beyer M. Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nat Commun. 2014 Jan 13; 5:3045.
Beutner C, Linnartz-Gerlach B, Schmidt SV, Beyer M, Mallmann MR, Staratschek-Jox A, Schultze JL, Neumann H. Unique transcriptome signature of mouse microglia. Glia. 2013 Sep 01; 61:1429-42.
Beyer M, Mallmann MR, Xue J, Staratschek-Jox A, Vorholt D, Krebs W, Sommer D, Sander J, Mertens C, Nino-Castro A, Schmidt SV, Schultze JL. High-resolution transcriptome of human macrophages. PLoS One. 2012 Jan 01; 7:e45466.
Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol. 2011 Aug 14; 12:898-907.
Beyer M, Kochanek M, Darabi K, Popov A, Jensen M, Endl E, Knolle PA, Thomas RK, von Bergwelt-Baildon M, Debey S, Hallek M, Schultze JL. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine.. Blood. 2005 Sep 15; 106:2018-25.

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