… to protect synapses in the striatum - the brain area first and most affected by Huntington’s and Parkinson’s disease, which relies on BDNF import from the cortex - from weakening and degeneration.
Memory…
… the analysis of proteins and functional protein networks associated with pathogenic gene variants causing Parkinson’s disease (PD). By systematically following the ‘guilt-by-association principle’ we aim at defining…
… / receptor systems, which typically show abnormalities in neurodegenerative diseases like e.g. Parkinson's disease. More recently, it has become possible to measure the cerebral distribution of…
… DZNE is a research center that addresses all aspects of neurodegenerative diseases (such as Alzheimer’s, Parkinson’s and Amyotrophic lateral sclerosis) in order to develop novel approaches of prevention, treatment,…
… focus of our research team has been on mechanisms of neurodegeneration and alpha-synuclein toxicity in Parkinson’s disease (PD). We have developed and characterized a variety of experimental models mimicking…
… are designated as neurodegenerative diseases. However, forms of dementia such as Alzheimer's and Parkinson's are better known among the general public, because with approximately 1.5 million people affected…
… nerve cells – is considered to be the main cause of neurodegenerative diseases like Alzheimer's, Parkinson's or prion diseases. As head of a new research group at the German Center for Neurodegenerative…
… sites across Germany. It is dedicated to diseases of the brain and nervous system, such as Alzheimer’s, Parkinson’s, and ALS, which are associated with dementia, movement disorders and other serious health…
… neurons, called synapses, are modulated and altered in neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. In addition to the study of neurodegenerative diseases, Al-Amoudi’s group closely…
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