• About

    5th Venusberg Meeting on Neuroinflammation

    11 – 13 May 2017

     

    Joan Miro, Illustración para Miró Litógrafo I, 1972 © VG Bild-Kunst, Bonn 2017


    Hosted by the German Center for Neurodegenerative Diseases (DZNE)
    and the University of Bonn.

    Location

    Source: DZNE/foerger

    German Center for Neurodegenerative Diseases
    DZNE lecture hall (ground floor)
    c/o University Clinic Bonn
    Building #99
    Sigmund-Freud-Straße 27
    53127 Bonn, Germany

     

    Contact

    Anne Thieme
    DZNE event management
    events(at)dzne.de
    +49 (0) 228 43302-266
    +49 (0) 151 6565 8421

    Lilly Hendricks
    DZNE event management
    events(at)dzne.de
    +49 (0) 228 43302-265
    +49 (0) 175 5744 890

    Sponsors

     
  • Registration

    Registration for this event is closed.

     

    According to § 4 No. 22a UStG (German Value Addes Tax Act), the conference fee is tax-free for all participants.

  • Program

    Download

    Download program flyer here.

  • Speakers

    Robert Baloh, California
    Dr. Baloh is Associate Professor of Neurology at Cedars-Sinai Medical Center and the University of California at Los Angeles.  He directs the Neuromuscular Medicine division as well as the ALS program at Cedars-Sinai, maintaining both an active clinical practice and research laboratory.  His interests are in understanding molecular and cellular mechanisms of neurodegeneration, with particular focus on amyotrophic lateral sclerosis and frontotemporal dementia.

    Source: UNM HSC Arnold

    Kiran Bhaskar, Albuquerque
    Dr. Kiran Bhaskar, PhD is an Assistant Professor of Molecular Genetics Microbiology and Neurology at the University of New Mexico, Albuquerque, NM, USA. Dr. Bhaskar and his lab studies the relationship between microglia-specific neuroinflammation and tau pathology using various disease models Alzheimer’s disease. His previous studies have shown that interleukin-1 beta (IL-1beta) secreted from reactive microglia induces pathological modifications in tau, which then leads to cognitive impairment and neurodegeneration. Dr. Bhaskar’s lab is currently understanding the mechanisms of inflammasomes activation and IL-1beta maturation in mouse models of tauopathy.

    Ajay Chawla, California

    Source: University of Illinois at Urbana Champaign

    Robert Dantzer, Houston
    Robert Dantzer is Professor and Deputy Chairman in the Department of Symptom Research at The University of Texas MD Anderson Cancer Center, Houston, Texas. He has conducted research for many years on the psychobiology of stress, the influence of neuropeptides on behavior, and the interactions between the immune system and the brain. His current research aims at understanding the role of inflammation in the development of depression and fatigue. He has authored or co-authored more than 400 original research papers and 120 book chapters on stress, anxiety, neuropeptides, and psychoneuroimmunology (h-index = 82).

    Philipp de Jager, Cambridge

    Source: private

    Guillaume Dorothee, Paris
    Guillaume Dorothée is a group leader in neuroimmunology at the French National Institute of Health and Medical Research (INSERM) in Saint-Antoine Hospital in Paris, France. He obtained his PhD in Immunology from University Pierre and Marie Curie (Paris), and trained as a postdoctoral fellow at Memorial Sloan-Kettering Cancer Center in New York, and Curie Institute in Paris. His current main research interests focus on understanding the role of neuroimmune interactions in the pathophysiology of neurodegenerative diseases, and developing innovative immunotherapy approaches and immune-based biomarkers in such conditions. Based on a translational research approach, a particular focus addresses the interplay between cellular adaptive immunity and innate neuroinflammation in Alzheimer's disease and related disorders.

    Giovanni Frisoni, Geneva

    Soure: Goodfellow

    Li Gan, California
    Dr. Gan studies the molecular mechanisms underlying the loss of neurons in neurodegenerative diseases, such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Her lab explores the relationship between the aging of neural circuits, the accumulation of toxic proteins, and the subsequent activation of a chronic inflammatory response. Understanding how these processes become dysfunctional in neurodegeneration could lead to new therapeutic strategies to tackle AD and FTD.

     

    Tony Wyss-Coray, Stanford

    Source: University of Florida

    Todd Golde, Florida
    Dr. Golde is a Professor of Neuroscience at the University of Florida, where he directs the McKnight Brain Institute and the 1Florida Alzheimer’s Disease Research Center. Formerly, he was director of the UF Center for Translational Research in Neurodegenerative Disease.  Dr. Golde has published over 225 peer-reviewed manuscripts which have been cited over 25,000 times. His scientific honors include Paul Beeson Faculty, Alzheimer’s Association Zenith, and MetLife Foundation Awards. He is also an active advocate for Alzheimer’s Disease and neurodegenerative disease research at the state, national, and international levels. He is an inventor on multiple patents relating to Alzheimer’s disease therapeutics.

    Source: University of Southampton

    Diego Gomez-Nicola, Southampton
    Diego Gomez-Nicola is a Lecturer in Neuroscience at Biological Sciences of the University of Southampton. Diego’s research interests range from the study of the dynamics and function of microglial cells in the healthy and ageing brain, to targeting neuroinflammation in the context of chronic neurodegenerative diseases like Alzheimer’s.

     

     

    Source: LMU

    Christian Haass, Munich
    Dr. Haass graduated in Molecular Biology at the University of Heidelberg, Germany.  He was a postdoc and assistant professor of Neurology at the Harvard Medical School in the institute of Dr. Dennis Selkoe.
    He was appointed as professor at the Central Institute of Mental Health in Mannheim in 1995. Since 1999 he is the head of the division of Biochemistry at the Ludwig-Maximilians-University and since 2009 he is also the speaker of the German Center for Neurodegenerative Diseases (DZNE) in Munich.
    His primary research areas are the molecular mechanisms of neurodegeneration with a focus on Alzheimer’s and Frontotemporal Dementia.
    He initiated the DFG-Forschungsschwerpunkt (National Priority Program) “Cellular Mechanisms of Alzheimer's Disease” and was speaker of the Collaborative Research Center (SFB 596) “Molecular Mechanisms of Neurodegeneration” from 2000 until 2012. Since 2012, he is speaker of the DFG Excellence Cluster "Systems Neurology" (SyNergy).
    Dr. Haass was member of the senate of the Deutsche Forschungsgemeinschaft (DFG) and he is elected member of the European Molecular Biology Organization (EMBO), the Leopoldina and the Bavarian Academy of Sciences and Humanities. He has received a number of prestigious awards, among them the Gottfried Wilhelm Leibniz-Award of the Deutsche Forschungsgemeinschaft, the Potamkin Award of the American Academy of Neurology, the Sheik Hamdan Award for Medical Sciences, the ERC advanced grant, a Honorary Degree of the University of Zurich, the Order of Merrit on Ribbon from the Federal Republic of Germany and the MetLife Foundation Award for Medical Research.

    John Hardy, London

    Eric J Huang, California

    Rudolf Jaenisch, Cambridge

    Mathew Blurton Jones, California

    Source: Ulf Sirborn

    Bertrand Joseph, Solna
    Bertrand Joseph is Professor in Molecular Cancer Biology at the Karolinska Institute, Stockholm Sweden. His group has particular interest in the signaling pathways controlling microglia activation in context of neurodegenerative disorders and brain tumors.

    Helmut Kettenmann, Berlin
    Helmut Kettenmann is  Research Group Leader at the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association and Professor for Cellular Neurobiology at the Humboldt University Berlin (Charité). His main research interest is the role of glial cells in health and disease. He has been Editor-in-Chief of the journal Glia since 1988.

    Julien Lagarde, Paris
    Julien Lagarde is a neurologist specialized in neurodegenerative diseases, especially Alzheimer's disease and related disorders in the Unit of Memory and Language Neurology at Saint-Anne Hospital in Paris, France (Head: Prof. Marie Sarazin). He obtained his MD in Neurology from University Paris Sud XI, and a Master 2 in cognitive neuroscience at University Pierre et Marie Curie (Paris VI). The current main research interests of the group of Prof. Marie Sarazin, to which he belongs, focus on understanding the interactions between amyloid and tau pathologies in AD, and the factors involved in modulating clinical presentation and symptoms evolution in neurodegenerative diseases, especially neuroinflammation, and developing new diagnostic and prognostic biomarkers. This work is based on a multimodal approach, combining clinical evaluation, blood and CSF biomarkers and morphological (MRI) and metabolic (PET) imaging data.

    Jean-Charles Lambert, Lille

    Greg Lemke, California
    Greg Lemke is the Françoise Gilot-Salk Professor at the Salk Institute. He received S.B. and Ph.D. degrees in biology from MIT and Caltech, respectively. He is a leader in the molecular genetic analysis of receptor tyrosine kinase signaling. He and his colleagues discovered important roles for ErbB receptors in cardiac and neural development, for EphA receptors in the topographic mapping of neuronal connections in the developing brain, and, most notably, for TAM receptors in immune homeostasis.

     

    Source: UVA Health System

    Antoine Louveau, Virginia
    Antoine Louveau, Research Scientist in the laboratory of Jonathan Kipnis at the University of Virginia, USA. After obtaining a PhD in neuroscience at the University of Nantes (France), my current work focuses on understanding the role of the meningeal lymphatic vasculature in the maintenance of brain function and the regulation of CNS specific immune responses.

    Urs Meyer
    Dr. Meyer is Professor of Pharmacology at the University of Zurich. His main research interests are centered upon the question of how early-life environmental adversities such as prenatal infection, pubertal stress, and nutritional imbalances can influence brain development and shape the risk of long-term brain abnormalities. His work combines behavioral and cognitive tests, immunological assays and neuroanatomical techniques in rodent models, including models of gene-environment and environment-environment interactions relevant to multifactorial neurodevelopmental disorders such as schizophrenia and autism.

    Source: Akshay Markanda

    Jonas Neher, Tübingen
    Jonas Neher is a group leader for Experimental Neuroimmunology at the Hertie Institute for Clinical Brain Research and the German Center for Neurodegenerative Diseases (DZNE) in Tübingen (Germany). He is particularly interested in the capacity of microglia for long-term molecular reprogramming ('innate immune memory') and their contribution to Alzheimer's Disease.

    Agneta Nordberg, Solna

    Marco Prinz, Freiburg

    Richard Ransohoff, Cambridge
    Richard M. Ransohoff received AB in Literature and Languages from Bard College and MD with honors from Case Western Reserve University School of Medicine (CWRU-SOM). After residency training in Internal Medicine and Neurology he performed postdoctoral research in the Department of Molecular Biology and Microbiology at CWRU-SOM. A staff neurologist at the Cleveland Clinic’s Mellen Center for MS Treatment and Research (1984-2014), he was cited in the “Best Doctors” compendium continuously from 1996-2014. He directed the Cleveland Clinic’s Neuroinflammation Research Center (2005-2014) and his research in chemokine action in the CNS was recognized by the John Dystel Prize for MS Research (2012). As Vice President, for the Neuroimmunology and Acute Neurology Research Units at Biogen (2014-date), his research interests focus on neuroinflammation in neurodegenerative and neurodevelopmental disease.

    Laurent Roybon, Lund

    Source: Cure Alzheimer’s Fund

    Sangram Sisodia, Chicago
    Dr. Sisodia’s research has focused on understanding the cellular and molecular biology of the amyloid precursor protein (APP) and presenilins (PS1 and PS2), polypeptides that are mutated in pedigrees with familial Alzheimer's Disease (FAD). His most notable contributions include the generation and characterization of mouse models that exhibit amyloid plaques in the brain. These models have been invaluable for understanding the impact of environmental enrichment and exercise in modulating amyloid deposition and adult neurogenesis. More recent studies have focused on the impact of the microbiome on modulation of Ab amyloidosis in mouse models. He has published 178 peer-reviewed manuscripts.
    Dr. Sisodia has received several awards, including: the Potamkin Prize for Alzheimer's Disease Research from the American Academy of Neurology and the Metropolitan Life Foundation Award for Medical Research. He was inducted as a Fellow of AAAS, and Foreign Fellow of the National Academy of Sciences, India and the Spanish Royal Academy of Sciences.  In addition, he has served as: Member, NLS1 (NIH) Study Section; Member, NIA Board of Scientific Counselors; Scientific Advisory Boards of Autism Speaks; the Packard Center for ALS Research; Chair, Scientific Advisory Committee of the Brain Research Foundation; and Advisory Committee of the MetLife Foundation. He has also organized, or co-organized several Adler Symposia on Alzheimer’s Disease at the Salk Institute, two Keystone Symposia, and was the co-director of the Cold Spring Harbor Neurobiology of Disease course.   Dr.Sisodia has served on the Editorial Boards of eight journals, including Neuron and Cell (10 year term expired in 2009), and is a member of the Dana Alliance for Brain Initiatives.

    Source: private

    Thor Stein, Boston
    Thor D. Stein, MD, PhD, is Associate Director of the Neuropathology Core, Boston University Alzheimer Disease Center, Assistant Professor of Pathology and Laboratory Medicine at Boston University School of Medicine and staff neuropathologist at the VA Boston Healthcare System. His research involves the role of genetics and environmental factors such as sports-related trauma in the development of quantitative pathologies in Alzheimer disease (AD) and chronic traumatic encephalopathy (CTE).

    Christoph Thaiss
    Christoph Thaiss received his BSc in Molecular Biomedicine from the University of Bonn, Germany, and his MSc in Microbiology and Immunology from Yale University, USA, and ETH Zurich, Switzerland. Following a visiting fellowship at the Broad Institute of MIT and Harvard, he has been performing his graduate studies in the lab of Eran Elinav at the Immunology Department of the Weizmann Institute of Science in Israel.
    His research interest is focused on the interactions of mammalian hosts with their commensal microbiota, as well as the consequences of the host-microbiome cross-talk on the development of human disease.

    Source: CNDD

    Federico Turkheimer, London
    Federico Turkheimer is Professor of Neuroimaging at King’s College London. An engineer by training, he has trained at NIMH (Bethesda) then worked at the University of Cambridge and Imperial College London in the UK. His main interest is the development of functional biomarkers using MRI and PET with application to neurological, neurodegenerative and psychiatric disorders.

    Source: CNIO

    Manuel Valiente, Madrid
    Manuel Valiente is the Head of the Brain Metastasis Group at CNIO (Madrid). His main goal is to discover critical aspects of the biology of brain secondary tumors in order to develop new therapeutic opportunities for this unmet clinical need.

  • Posters

    All poster abstracts are available for download here.


    All posters will be set-up during all three conference days and will be presented by the respective authors during each lunch break as follows:

    Poster Session 1: Thursday, 11th May, 13:00 - 14:30
    Poster #1 - #20 will be presented.

    Poster Session 2: Friday, 12th May, 12:15 - 14:00
    Poster #21 - #40 will be presented.

    Poster Session 3: Saturday, 13th May, 12:45 - 14:15
    Poster #40 - #65 will be presented.


    Please note: Poster size may not exceed DIN A0.

     

     

  • Directions

    Directions to the conference venue DZNE...

    Arriving via Cologne/Bonn airport

    Take bus SB60, direction "Bonn Hbf" (Bonn Hauptbahnhof = Bonn main station) and get off at "Bonn Hauptbahnhof". The busses usually run every 30 minutes. The bus ride takes about 30 - 40 minutes, depending on the traffic.

    Arriving via Frankfurt airport

    There are several train connections to arrive in Bonn (main station). The fastest connection is taking an ICE train from Frankfurt aiport to "Siegburg Hbf" (Siegburg main station). The train ride takes about 25 - 30 minutes. In Siegburg, take the tram 66, direction "Bad Honnef" and get off at "Bonn Hbf" (Bonn main station). The tram ride takes about 25 - 30 minutes.

    Arriving via Bonn main station ("Hauptbahnhof")

    Take bus 601, direction "Uniklinikum Süd" and get off at the last stop "Uniklinikum Süd". You can already see the DZNE from the bus stop. The busses usually run every 10 minutes. The bus ride takes about 20 - 30 minutes, depending on the traffic.

    National railway system

    The German railway system is operated by the company Deutsche Bahn (DB).
    Book a train connection via bahn.de.

    Public Transportation in Bonn

    Bonn and Cologne are connected through one public transportation system, operated by the company vrs.
    To research a bus, tram or regional train connection, please go to vrsinfo.de.

    Taxi Bonn

    The biggest taxi company in Bonn is Taxi Bonn.
    Call a taxi by dialing +49 (0) 228 555 555.

    Hotel Recommendations

    Any hotels in the area of "Bonn-Venusberg", "Bonn-Poppelsdorf" and "Bonn-center" are conveniently located and within short distance to the conference venue.

    Possible options include:

    InterCity Hotel Bonn Center

    Youth Hostel Bonn Venusberg

    Hotel MyPoppelsdorf

    President Hotel

    Maps

    University Clinic
    DZNE on the premises of the University Clinic