Background and aims
Spinocerebellar Ataxies (SCA) are autosomal dominant inherited ataxia diseases. The SCA Registry builds on the EUROSCA and RISCA cohort studies funded by the EU since 2004. It includes high-risk individuals and patients with manifest ataxia of all SCA genotypes including the more common polyglutamine SCAs (SCA1, SCA2, SCA3, SCA6).
The objectives of the SCA Registry are to characterise the natural progression of the disease, identify prognostic factors and develop new imaging and biochemical biomarkers. By including risk persons, special emphasis is given to the investigation of the pre-clinical phase of the disease. The studies conducted under the SCA Registry are an immediate preparation of ongoing and future treatment studies.
Further information and contact data are available here.
Principle Investigator: Prof. Dr. Thomas Klockgether
Status: multi centric, ongoing, recruiting active