Nuclear architecture in neural plasticity and aging

Dr. Tomohisa Toda


The complete list of publications can be found here.

Bedrosian TA, Houtman J, Eguiguren JS, Ghassemzadeh S, Rund N, Novaresi NM, Hu L, Parylak SL, Denli AM, Randolph-Moore L, Namba T, Gage FH, Toda T. Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis. EMBO J. 2020 Dec 10; e105819 doi: 10.15252/embj.2020105819
Schlachetzki JCM, Toda T*, Mertens J*. (*Co-corresponding). When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging neuron. Exp Gerontol. 2020 May 01; 133 doi: 10.1016/j.exger.2020.110876
Toda T, Parylak SL, Linker SB, Gage FH. The role of adult hippocampal neurogenesis in brain health and disease. Mol Psychiatry. 2019 Jan 20; 24:67-87. doi: 10.1038/s41380-018-0036-2
Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, Jacinto FV, Hetzer MW, Gage FH. Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells. Cell Stem Cell. 2017 Feb 02; 21:618-634. doi: 10.1016/j.stem.2017.08.012
Toda T, Shinmyo Y, Dinh Duong TA, Masuda K, Kawasaki H. An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals. Sci Rep. 2016 Jul 12; 6 doi: 10.1038/srep29578
Hoshiba Y, Toda T, Ebisu H, Wakimoto M, Yanagi S, Kawasaki H. Sox11 Balances Dendritic Morphogenesis with Neuronal Migration in the Developing Cerebral Cortex. J Neurosci. 2016 May 25; 36:5775-84. doi: 10.1523/JNEUROSCI.3250-15.2016
Masuda K*, Toda T*, Shinmyo Y*, Ebisu H, Hoshiba Y, Wakimoto M, Ichikawa Y, Kawasaki H. (*equal contributions. Pathophysiological analyses of cortical malformation using gyrencephalic mammals. Sci Rep. 2015 Oct 20; 5:15370. doi: 10.1038/srep15370
Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S,Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. Cell Stem Cell. 2015 Dec 03; 17:705-718. doi: 10.1038/srep15370
Toda T, Kawasaki H. The development of suckling behavior of neonatal mice is regulated by birth. Mol Brain. 2014 Feb 10; 7 doi: 10.1186/1756-6606-7-8
Toda T, Homma D, Tokuoka H, Hayakawa I, Sugimoto Y, Ichinose H, Kawasaki H. Birth regulates the initiation of sensory map formation through serotonin signaling. Dev Cell. 2013 Oct 14; 27:32-46. doi: 10.1016/j.devcel.2013.09.002
Sehara K*, Toda T*, Iwai L*, Wakimoto M, Tanno K, Matsubayashi Y, Kawasaki H.(*equal contributions). Whisker-related axonal patterns and plasticity of layer 2/3 neurons in the mouse barrel cortex. J Neurosci. 2010 Feb 24; 30:3082-92. doi: 10.1523/JNEUROSCI.6096-09.2010
Toda T, Hayakawa I, Matsubayashi Y, Tanaka K, Ikenaka K, Lu QR, Kawasaki H. Termination of lesion-induced plasticity in the mouse barrel cortex in the absence of oligodendrocytes. Mol Cell Neurosci. 2008 Sep 01; 39:40-9. doi: 10.1016/j.mcn.2008.05.014

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