Mechanisms of induced plasticity of the vertebrate brain
Dr. Caghan Kizil
Group Leader
Tatzberg 41
01307 Dresden
 +49 351 210 463-610


The complete list of publications is found here.

Mehmet I. Cosacak, Prabesh Bhattarai, Ledio Bocova, Tim Dzewas, Violeta Mashkaryan, Christos Papadimitriou, Kerstin Brandt, Heike Hollak, Christopher L. Antos, Caghan Kizil. Human TAUP301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain. Scientific Reports. 2017 Nov 30; 7 doi: 10.1038/s41598-017-13311-5
Prabesh Bhattarai, Alvin Kuriakose Thomas, Mehmet Ilyas Cosacak, Christos Papadimitriou, Violeta Mashkaryan, Yixin Zhang, Caghan Kizil. Modeling amyloid-β42 toxicity and neurodegeneration in adult zebrafish brain. Journal of Visualized Experiments. 2017 Oct 24; 2017 doi: 10.3791/56014
Bhattarai P, Thomas AK, Zhang Y, Kizil C. The effects of ageing on Amyloid-42-induced neurodegeneration and regeneration in adult zebrafish brain. Neurogenesis. 2017 Jan 01; 4:e1322666.
Prabesh Bhattarai, Alvin Kuriakose Thomas, Mehmet Ilyas Cosacak, Christos Papadimitriou, Violeta Mashkaryan, Cynthia Froc, Susanne Reinhardt, Thomas Kurth, Andreas Dahl, Yixin Zhang, Caghan Kizil. IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. Cell Reports. 2016 Oct 17; 17:941-948. doi: 10.1016/j.celrep.2016.09.075
Gizem Tincer, Violeta Mashkaryan, Prabesh Bhattarai, Caghan Kizil. Neural stem/progenitor cells in Alzheimer’s disease. Yale Journal of Biology and Medicine. 2016 Feb 29; 89:23-35.
Caghan Kizil, Nikos Kyritsis, Michael Brand. Effects of inflammation on stem cells: Together they strive?. EMBO Reports. 2015 Mar 31; 16:416-426. doi: 10.15252/embr.201439702
Mehmet Ilyas Cosacak, Christos Papadimitriou, Caghan Kizil. Regeneration, Plasticity, and Induced Molecular Programs in Adult Zebrafish Brain. BioMed Research International. 2014 Dec 31; 2015 doi: 10.1155/2015/769763
Caghan Kizil, Anne Iltzsche, Alvin Kuriakose Thomas, Prabesh Bhattarai, Yixin Zhang, Michael Brand. Efficient cargo delivery into adult brain tissue using short cell-penetrating peptides. PLoS ONE. 2015 Apr 19; 10 doi: 10.1371/journal.pone.0124073
Caghan Kizil, Beate Küchler, Jia-Jiun Yan, Günes Özhan, Enrico Moro, Francesco Argenton, Michael Brand, Gilbert Weidinger, Christopher L. Antos. Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development (Cambridge). 2013 Dec 31; 141:3529-3539. doi: 10.1242/dev.108415
Kyritsis N*, Kizil C*, Brand M. (* equal contribution). The role of neuroinflammation in central nervous system regeneration. Trends in Cell Biology. 2014 Jan 01; 24:128-35.
Kizil C, Kyritsis N, Dudczig S, Kroehne V, Freudenreich F, Kaslin J, Brand M. Regenerative neurogenesis from neural progenitor cells requires injury-induced expression of Gata3. Developmental Cell. 2012 Jan 01; 23:1230-1237.
Kyritsis N, Kizil C, Kroehne V, Zocher S, Kaslin J, Freudenreich D, Iltzsche A, Brand M. Acute inflammation initiates the regenerative response in the adult zebrafish brain. Science. 2012 Jan 01; 338:1353-1356.
Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M. The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain. Neural Development. 2012 Jan 01; 7:27.
Kizil C, Kaslin J, Kroehne V, Brand M. Adult neurogenesis and brain regeneration in zebrafish. Developmental Neurobiology. 2012 Jan 01; 72:429-461.
Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL. Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Developmental Biology. 2009 Jan 01; 352:329-40.


Thursdays 1:30-4:30 pm

Patients +49 800-7799001

(free of charge)

Professionals +49 180-779900

(9 Cent/Min. German landline, mobile and out of Germany possibly more expensive)