Publications


Nicolai Franzmeier, Julia Hartmann, Alexander N. W. Taylor, Miguel Á. Araque-Caballero, Lee Simon-Vermot, Lana Kambeitz-Ilankovic, Katharina Bürger, Cihan Catak, Daniel Janowitz, Claudia Müller, Birgit Ertl-Wagner, Robert Stahl, Martin Dichgans, Marco Duering, Michael Ewers. The left frontal cortex supports reserve in aging by enhancing functional network efficiency Rik Ossenkoppele. Alzheimer's Research and Therapy. 2018 Mar 05; 10 doi: 10.1186/s13195-018-0358-y
Marrone L, Bus C, Schöndorf D, Fitzgerald F, Kübler M, Schmid B, Reinhardt P, Deleidi M, Levin T, Meixner A, Klink B, Glatza M, Gloeckner CJ, Gasser T, Sterneckert J. Generation of iPSCs stratified for a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS One. 2018 Mar 04; 13:e0192497. doi: 10.1371/journal.pone.0192497
Plescher M, Seifert G, Hansen JN, Bedner P, Steinhäuser C, Halle A. Plaque-dependent morphological and electrophysiological heterogeneity of microglia in an Alzheimer's disease mouse model. Glia. 2018 Mar 01; [Epub ahead of print] doi: 10.1002/glia.23318
Haupt, Jessen, Fangerau. Advance directive of probands in pharmaceutical research: A medical ethics discussion. Nervenarzt. 2018 Feb 28; 89:335-341. doi: 10.1007/s00115-017-0392-1
Fliessbach, Schneider. Biomarker-based diagnostics of Alzheimer’s disease: Concept of suspected non-Alzheimer pathology. Nervenarzt. 2018 Feb 28; 89:345-358. doi: 10.1007/s00115-018-0488-2
Gerd Wallukat, Harald Prüss, Johannes Müller, Ingolf Schimke. Functional autoantibodies in patients with different forms of dementia. PLoS ONE. 2018 Feb 28; 13 doi: 10.1371/journal.pone.0192778
Thomas Arzberger, Martin H. Schludi, Carina Lehmer, Bettina Schmid, Dieter Edbauer. RNA versus protein toxicity in C9orf72 ALS/FTLD. Acta Neuropathologica. 2018 Feb 28; 135:475-479. doi: 10.1007/s00401-018-1823-1
Esther Kuehn, Mario Borja Perez-Lopez, Nadine Diersch, Juliane Döhler, Thomas Wolbers, Martin Riemer. Embodiment in the aging mind. Neuroscience and Biobehavioral Reviews. 2018 Feb 28; 86:207-225. doi: 10.1016/j.neubiorev.2017.11.016
Lara Marrone, Christine Bus, David Schöndorf, Julia Catherine Fitzgerald, Manuela Kübler, Benjamin Schmid, Peter Reinhardt, Lydia Reinhardt, Michela Deleidi, Tanya Levin, Andrea Meixner, Barbara Klink, Michael Glatza, Christian Johannes Gloeckner, Thomas Gasser, Jared Sterneckert. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson’s disease. PLoS ONE. 2018 Feb 28; 13 doi: 10.1371/journal.pone.0192497
Wolfgang Hoffmann, Ina Zwingmann, Neeltje van den Berg, Josefin Biermann. German congress for healthcare research: Solutions and innovations for German health policy in the new legislative period. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 2018 Feb 28; 61:367-370. doi: 10.1007/s00103-018-2698-y
Nicolaas I. Bohnen, Michel J. Grothe, Nicola J. Ray, Martijn L. T. M. Müller, Stefan J. Teipel. Recent Advances in Cholinergic Imaging and Cognitive Decline—Revisiting the Cholinergic Hypothesis of Dementia. Current Geriatrics Reports. 2018 Feb 28; 7 doi: 10.1007/s13670-018-0234-4
Kiterie M E Faller, Dorothee Atzler, Debra J McAndrew, Sevasti Zervou, Hannah J Whittington, Jillian N Simon, Dunja Aksentijevic, Michiel Ten Hove, Chi-Un Choe, Dirk Isbrandt, Barbara Casadei, Jurgen E Schneider, Stefan Neubauer, Craig A Lygate. Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine. Cardiovascular Research. 2018 Feb 28; 114:417-430. doi: 10.1093/cvr/cvx242
Brian A Gordon, Tyler M Blazey, Yi Su, Amrita Hari-Raj, Aylin Dincer, Shaney Flores, Jon Christensen, Eric McDade, Guoqiao Wang, Chengjie Xiong, Nigel J Cairns, Jason Hassenstab, Daniel S Marcus, Anne M Fagan, Clifford R Jack, Russ C Hornbeck, Katrina L Paumier, Beau M Ances, Sarah B Berman, Adam M Brickman, David M Cash, Jasmeer P Chhatwal, Stephen Correia, Stefan Förster, Nick C Fox, Neill R Graff-Radford, Christian la Fougère, Johannes Levin, Colin L Masters, Martin N Rossor, Stephen Salloway, Andrew J Saykin, Peter R Schofield, Paul M Thompson, Michael M Weiner, David M Holtzman, Marcus E Raichle, John C Morris, Randall J Bateman, Tammie L S Benzinger. Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. The Lancet Neurology. 2018 Feb 28; 17:241-250. doi: 10.1016/S1474-4422(18)30028-0
David Brenner, Rüstem Yilmaz, Kathrin Müller, Torsten Grehl, Susanne Petri, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Wolfgang Ruf, Christoph Neuwirth, Markus Weber, Susana Pinto, Kristl G. Claeys, Berthold Schrank, Berit Jordan, Antje Knehr, Kornelia Günther, Annemarie Hübers, Daniel Zeller, Christian Kubisch, Sibylle Jablonka, Michael Sendtner, Thomas Klopstock, Mamede De Carvalho, Anne Sperfeld, Guntram Borck, Alexander E. Volk, Johannes Dorst, Joachim Weis, Markus Otto, Joachim Schuster, Kelly Del Tredici, Heiko Braak, Karin M. Danzer, Axel Freischmidt, Thomas Meitinger, Tim M. Strom, Albert C. Ludolph, Peter M. Andersen, Jochen H. Weishaupt, Ute Weyen, Andreas Hermann, Tim Hagenacker, Jan Christoph Koch, Paul Lingor, Bettina Göricke, Stephan Zierz, Petra Baum, Joachim Wolf, Andrea Winkler, Peter Young, Ulrich Bogdahn, Johannes Prudlo, Jan Kassubek. Hot-spot KIF5A mutations cause familial ALS. Brain. 2018 Feb 28; 141:688-697. doi: 10.1093/brain/awx370
Antonio F. Pardiñas, Peter Holmans, Andrew J. Pocklington, Valentina Escott-Price, Stephan Ripke, Noa Carrera, Sophie E. Legge, Sophie Bishop, Darren Cameron, Marian L. Hamshere, Jun Han, Leon Hubbard, Amy Lynham, Kiran Mantripragada, Elliott Rees, James H. MacCabe, Steven A. McCarroll, Bernhard T. Baune, Gerome Breen, Enda M. Byrne, Udo Dannlowski, Thalia C. Eley, Caroline Hayward, Nicholas G. Martin, Andrew M. McIntosh, Robert Plomin, David J. Porteous, Naomi R. Wray, Armando Caballero, Daniel H. Geschwind, Laura M. Huckins, Douglas M. Ruderfer, Enrique Santiago, Pamela Sklar, Eli A. Stahl, Hyejung Won, Esben Agerbo, Thomas D. Als, Ole A. Andreassen, Marie Bækvad-Hansen, Preben Bo Mortensen, Carsten Bøcker Pedersen, Anders D. Børglum, Jonas Bybjerg-Grauholm, Srdjan Djurovic, Naser Durmishi, Marianne Giørtz Pedersen, Vera Golimbet, Jakob Grove, David M. Hougaard, Manuel Mattheisen, Espen Molden, Ole Mors, Merete Nordentoft, Milica Pejovic-Milovancevic, Engilbert Sigurdsson, Teimuraz Silagadze, Christine Søholm Hansen, Kari Stefansson, Hreinn Stefansson, Stacy Steinberg, Sarah Tosato, Thomas Werge, Denise Harold, Rebecca Sims, Amy Gerrish, Jade Chapman, Richard Abraham, Paul Hollingworth, Jaspreet Pahwa, Nicola Denning, Charlene Thomas, Sarah Taylor, John Powell, Petroula Proitsi, Michelle Lupton, Simon Lovestone, Peter Passmore, David Craig, Bernadette McGuinness, Janet Johnston, Stephen Todd, Wolfgang Maier, Frank Jessen, Reiner Heun, Britta Schurmann, Alfredo Ramirez, Tim Becker, Christine Herold, André Lacour, Dmitriy Drichel, Markus Nothen, Alison Goate, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, Michael O'Donovan, Michael Owen, Julie Williams, Evanthia Achilla, Cathy L. Barr, Theresa Wimberly Böttger, Dan Cohen, Sarah Curran, Emma Dempster, Danai Dima, Ramon Sabes-Figuera, Robert J. Flanagan, Sophia Frangou, Josef Frank, Christiane Gasse, Fiona Gaughran, Ina Giegling, Eilis Hannon, Annette M. Hartmann, Barbara Heißerer, Marinka Helthuis, Henriette Thisted Horsdal, Oddur Ingimarsson, Karel Jollie, James L. Kennedy, Ole Köhler, Bettina Konte, Maren Lang, Cathryn Lewis, James MacCaba, Anil K. Malhotra, Paul McCrone, Sandra M. Meier, Jonathan Mill, Markus M. Nöthen, Carsten B. Pedersen, Marcella Rietschel, Dan Rujescu, Ameli Schwalber, Holger J. Sørensen, Benjamin Spencer, Henrik Støvring, Jana Strohmaier, Patrick Sullivan, Evangelos Vassos, Moira Verbelen, David A. Collier, George Kirov, Michael J. Owen, Michael C. O'Donovan, James T. R. Walters. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics. 2018 Feb 28; 50:381-389. doi: 10.1038/s41588-018-0059-2
Niamh M.C. Connolly, Pierre Theurey, Vera Adam-Vizi, Nicolas G. Bazan, Paolo Bernardi, Juan P. Bolaños, Carsten Culmsee, Valina L. Dawson, Mohanish Deshmukh, Michael R. Duchen, Heiko Düssmann, Gary Fiskum, Maria F. Galindo, Giles E. Hardingham, J. Marie Hardwick, Mika B. Jekabsons, Elizabeth A. Jonas, Joaquin Jordán, Stuart A. Lipton, Giovanni Manfredi, Mark P. Mattson, BethAnn McLaughlin, Axel Methner, Anne N. Murphy, Michael P. Murphy, David G. Nicholls, Brian M. Polster, Tullio Pozzan, Rosario Rizzuto, Jorgina Satrústegui, Ruth S. Slack, Raymond A. Swanson, Russell H. Swerdlow, Yvonne Will, Zheng Ying, Alvin Joselin, Anna Gioran, Catarina Moreira Pinho, Orla Watters, Manuela Salvucci, Irene Llorente-Folch, David S. Park, Daniele Bano, Maria Ankarcrona, Paola Pizzo, Jochen H.M. Prehn. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. 2018 Feb 28; 25:542-572. doi: 10.1038/s41418-017-0020-4
Christoph Kessler, Burcu Atasu, Hasmet Hanagasi, Javier Simón-Sánchez, Ann-Kathrin Hauser, Meltem Pak, Basar Bilgic, Nihan Erginel-Unaltuna, Hakan Gurvit, Thomas Gasser, Ebba Lohmann. Role of LRRK2 and SNCA in autosomal dominant Parkinson's disease in Turkey. Parkinsonism and Related Disorders. 2018 Feb 28; 48:34-39. doi: 10.1016/j.parkreldis.2017.12.007
Franc Llorens, Niels Kruse, André Karch, Matthias Schmitz, Saima Zafar, Nadine Gotzmann, Ting Sun, Silja Köchy, Tobias Knipper, Maria Cramm, Ewa Golanska, Beata Sikorska, Pawel P. Liberski, Raquel Sánchez-Valle, Andre Fischer, Brit Mollenhauer, Inga Zerr. Validation of α-Synuclein as a CSF Biomarker for Sporadic Creutzfeldt-Jakob Disease. Molecular Neurobiology. 2018 Feb 28; 55:2249-2257. doi: 10.1007/s12035-017-0479-5
Maria Perez Carrion, Francesca Pischedda, Alice Biosa, Isabella Russo, Letizia Straniero, Laura Civiero, Marianna Guida, Christian J. Gloeckner, Nicola Ticozzi, Cinzia Tiloca, Claudio Mariani, Gianni Pezzoli, Stefano Duga, Irene Pichler, Lifeng Pan, John E. Landers, Elisa Greggio, Michael W. Hess, Stefano Goldwurm, Giovanni Piccoli. The LRRK2 variant E193K prevents mitochondrial fission upon MPP+ treatment by altering LRRK2 binding to DRP1. Frontiers in Molecular Neuroscience. 2018 Feb 27; 11 doi: 10.3389/fnmol.2018.00064
Boya P, Codogno P, Rodriguez-Muela N. Autophagy in stem cells: repair, remodeling, and metabolic reprogramming. Development. 2018 Feb 26; 145 doi: 10.1242/dev.146506
René Günther, Wiebke Schrempf, Antje Hähner, Thomas Hummel, Martin Wolz, Alexander Storch, Andreas Hermann. Impairment in respiratory function contributes to olfactory impairment in amyotrophic lateral sclerosis. Frontiers in Neurology. 2018 Feb 25; 9 doi: 10.3389/fneur.2018.00079
Frederic Brosseron, Andreas Traschütz, Catherine N. Widmann, Markus P. Kummer, Pawel Tacik, Francesco Santarelli, Frank Jessen, Michael T. Heneka. Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease. Alzheimer's Research and Therapy. 2018 Feb 25; 10 doi: 10.1186/s13195-018-0353-3
Kan Xie, Devon P. Ryan, Brandon L. Pearson, Kristin S. Henzel, Frauke Neff, Ramon O. Vidal, Magali Hennion, Isabelle Lehmann, Melvin Schleif, Susanne Schröder, Thure Adler, Birgit Rathkolb, Jan Rozman, Anna-Lena Schütz, Cornelia Prehn, Michel E. Mickael, Marco Weiergräber, Jerzy Adamski, Dirk H. Busch, Gerhard Ehninger, Anna Matynia, Walker S. Jackson, Eckhard Wolf, Helmut Fuchs, Valerie Gailus-Durner, Stefan Bonn, Martin Hrabě de Angelis, Dan Ehninger. Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice. Proc Natl Acad Sci USA. 2018 Feb 21; doi: 10.1073/pnas.1707337115
Colombo A, Hsia HE, Wang M, Kuhn PH, Brill MS, Canevazzi P, Feederle R, Taveggia C, Misgeld T, Lichtenthaler SF. Non‐cell‐autonomous function of DR6 in Schwann cell proliferation. EMBO J. 2018 Feb 19; 37:e97390. doi: 10.15252/embj.201797390
Nàdia Villacampa, Michael T. Heneka. Microglia: You'll Never Walk Alone!. Immunity. 2018 Feb 19; 48:195-197. doi: 10.1016/j.immuni.2018.02.009
Martin Riemer, Thomas Wolbers. Negative errors in time reproduction tasks. Psychological Research. 2018 Feb 18; :1-9. doi: 10.1007/s00426-018-0994-7
Ilaria Bellantuono, Rafael de Cabo, Dan Ehninger, Adelaide Fernandez, Susan E. Howlett, Ralph Müller, Paul K. Potter, Anne-Ulrike Trendelenburg, Jose L. Trejo, Roosmarijn E. Vandenbroucke, Ronald van Os, Natal A. W. van Riel. Find drugs that delay many diseases of old age. Nature. 2018 Feb 15; 554:293-295. doi: 10.1038/d41586-018-01668-0
Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain. 2018 Feb 15; doi: 10.1093/brain/awy008
Lara Marrone, Ina Poser, Ian Casci, Julia Japtok, Peter Reinhardt, Antje Janosch, Cordula Andree, Hyun O. Lee, Claudia Moebius, Ellen Koerner, Lydia Reinhardt, Maria Elena Cicardi, Karl Hackmann, Barbara Klink, Angelo Poletti, Simon Alberti, Marc Bickle, Andreas Hermann, Udai Bhan Pandey, Anthony A. Hyman, Jared L. Sterneckert. Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy. Stem Cell Reports. 2018 Feb 12; 10:375-389. doi: 10.1016/j.stemcr.2017.12.018
Mehmet Ilyas Cosacak, Hatice Yiğit, Caghan Kizil, Bünyamin Akgül. Re-arrangements in the cytoplasmic distribution of small RNAs following the maternal-to-zygotic transition in Drosophila embryos. Genes. 2018 Feb 09; 9 doi: 10.3390/genes9020082

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