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Publikationen

Follow-Up Study of the First Genome-Wide Association Scan in Alopecia Areata: IL13 and KIAA0350 as Susceptibility Loci Supported with Genome-Wide Significance.

Jagielska D, Redler S, Brockschmidt FF, Herold C, Pasternack SM, Garcia Bartels N, Hanneken S, Eigelshoven S, Refke M, Barth S, Giehl KA, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Blume-Peytavi U, Becker T, Nöthen MM, Betz RC. J Invest Dermatol. 2012 Apr 26. doi: 10.1038/jid.2012.129. [Epub ahead of print]

Integrated Genome-Wide Pathway Association Analysis with INTERSNP.

Herold C, Mattheisen M, Lacour A, Vaitsiakhovich T, Angisch M, Drichel D, Becker T. Hum Hered. 2012 Mar 7;73(2):63-72. [Epub ahead of print]

Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata.

Forstbauer LM, Brockschmidt FF, Moskvina V, Herold C, Redler S, Herzog A, Hillmer AM, Meesters C, Heilmann S, Albert F, Alblas M, Hanneken S, Eigelshoven S, Giehl KA, Jagielska D, Blume-Peytavi U, Garcia Bartels N, Kuhn J, Hennies HC, Goebeler M, Jung A, Peitsch WK, Kortüm AK, Moll I, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Kirov G, Becker T, Nöthen MM, Betz RC. Eur J Hum Genet. 2012 Mar;20(3):326-32. doi: 10.1038/ejhg.2011.185. Epub 2011 Oct 26.

Methylation of L1Hs promoters is lower on the inactive X, has a tendency of being higher on autosomes in smaller genomes and shows inter-individual variability at some loci.

H Singer, M Walier, N Nüsgen, C Meesters, F Schreiner, J Woelfle, R Fimmers, T Wienker, VM Kalscheuer, T Becker, R Schwaab, J Oldenburg, O El-Maarri; Hum Mol Genet. 2012 Jan 1;21(1):219-35. Epub 2011 Oct 4.

Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness.

FF Brockschmidt, S Heilmann, JA Ellis, S Eigelshoven, S Hanneken, C Herold, S Moebus, MA Alblas, B Lippke, N Kluck, L Priebe, FA Degenhardt, RA Jamra, C Meesters, KH Jöckel, R Erbel, S Harrap, J Schumacher, H Fröhlich, R Kruse, AM Hillmer, T Becker, MM Nöthen; Br J Dermatol. 2011 Dec;165(6):1293-302. doi: 10.1111/j.1365-2133.2011.10708.x.

The modulation of Amyotrophic Lateral Sclerosis risk by Ataxin-2 intermediate polyglutamine expansions is a specific effect.

S Gispert, A Kurz, S Waibel, P Bauer, I Liepelt, C Geisen, AD Gitler, T Becker, M Weber, D Berg, PM Andersen, R Krüger, O Riess, AC Ludolph, G Auburger; Neurobiol Dis. 2011 Aug 25. [Epub ahead of print]

Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss

S Redler, MP Birch, D Drichel, K Dobson, FF Brockschmidt, R Tazi-Ahnini, KA Giehl, N Kluck, R Kruse, G Lutz, H Wolff, T Becker, MM Nöthen, AG Messenger, RC Betz; Br J Dermatol. 2011 Sep;165(3):703-705. doi: 10.1111/j.1365-2133.2011.10456.x. Epub 2011 Aug 4.

Significance Levels in Genome-Wide Interaction Analysis (GWIA).

Becker T, Herold C, Meesters C, Mattheisen M, Baur MP, Ann Hum Genet. 2011 Jan;75(1):29-35. doi: 10.1111/j.1469-1809.2010.00610.x. Epub 2010 Oct 18.

Feasible and Successful: Genome-Wide Interaction Analysis Involving All 1.9 × 1011 Pair-Wise Interaction Tests.

M Steffens, T Becker, T Sander, R Fimmers, C Herold, DA Holler, C Leu, S Herms, S Cichon, B Bohn, T Gerstner, M Griebel, MM Nöthen, TF Wienker, MP Baur (2010), Hum Hered 69:268-284

Fine mapping of the human AR/EDA2R locus in androgenetic alopecia.

Brockschmidt FF, Hillmer AM, Eigelshoven S, Hanneken S, Heilmann S, Barth S, Herold C, Becker T, Kruse R, Nöthen MM (2010), Br J Dermatol. 2010 Mar 1

Association study of 20 genetic variants at the D-amino acid oxidase gene in schizophrenia.

Suliman H, Schumacher J, Becker T, Cichon S, Schulze TG, Propping P, Rietschel M, Nöthen MM, Jamra RA. (2010), Psychiatr Genet. 2010 Feb 6.

DNA sequence variants of the FKBP5 gene are associated with unipolar depression.

Zobel A, Schuhmacher A, Jessen F, Höfels S, von Widdern O, Metten M, Pfeiffer U, Hanses C, Becker T, Rietschel M, Scheef L, Block W, Schild HH, Maier W, Schwab SG (2010), Int J Neuropsychopharmacol

Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6.

Stanke F, Becker T, Hedtfeld S, Tamm S, Wienker TF, Tümmler B (2010), Hum Genet 127:383-394

The TRAF1/C5 locus confers risk for familial and severe alopecia areata.

Redler S, Brockschmidt FF, Forstbauer L, Giehl KA, Herold C, Eigelshoven S, Hanneken S, De Weert J, Lutz G, Wolff H, Kruse R, Blaumeiser B, Böhm M, Becker T, Nöthen MM, Betz RC (2010), Br J Dermatol 2009 Dec 17.

INTERSNP: genome-wide interaction analysis guided by a priori information.

C Herold, M Steffens, FF Brockschmidt, MP Baur, T Becker; Bioinformatics. 2009 Dec 15.

Replication of LCE3C-LCE3B CNV as a Risk Factor for Psoriasis and Analysis of Interaction with Other Genetic Risk Factors.

Hüffmeier U, Bergboer JG, Becker T, Armour JA, Traupe H, Estivill X, Riveira-Munoz E, Mössner R, Reich K, Kurrat W, Wienker TF, Schalkwijk J, Zeeuwen PL, Reis A (2010), J Invest Dermatol 130:979-984

A systematic association mapping on chromosome 6q in bipolar affective disorder-evidence for the melanin-concentrating-hormone-receptor-2 gene as a risk factor for bipolar affective disorder.

Abou Jamra R, Schulze TG, Becker T, Brockschmidt FF, Green E, Alblas MA, Wendland JR, Adli M, Grozeva D, Strohmeier J, Georgi A, Craddock N, Propping P, Rietschel M, Nöthen MM, Cichon S, Schumacher J (2009), Am J Med Genet B Neuropsychiatr Genet 2009 Nov 19.

INTERSNP: Genome-wide Interaction Analysis Guided by A Priori Information.

Herold C, Steffens M, Brockschmidt FF, Baur MP, Becker T (2009), Bioinformatics 25: 3275-3281

Characterization of Psoriasis Susceptibility Locus 6 (PSORS6) in Patients with Early Onset Psoriasis and Evidence for Interaction with PSORS1.

Hüffmeier U, Lascorz J, Becker T, Schürmeier-Horst F, Magener A, Ekici AB, Endele S, Thiel CT, Thoma-Uszynski S, Mössner R, Reich K, Kurrat W, Wienker TF, Traupe H, Reis A. (2009), J Med Genet 46:736-44

Genetic variation in the schizophrenia-risk gene neuregulin 1 correlates with brain activation and impaired speech production in a verbal fluency task in healthy individuals.

Kircher T, Krug A, Markov V, Whitney C, Krach S, Zerres K, Eggermann T, Stöcker T, Shah NJ, Treutlein J, Nöthen MM, Becker T, Rietschel M (2009), Hum Brain Mapp 30:3406-16

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD.

Scholl HP, Fleckenstein M, Fritsche LG, Schmitz-Valckenberg S, Göbel A, Adrion C, Herold C, Keilhauer CN, Mackensen F, Mössner A, Pauleikhoff D, Weinberger AW, Mansmann U, Holz FG, Becker T, Weber BH (2009), PLoS One. 2009 Oct 12;4(10):e7418.

Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power.

Becker T, Herold C (2009), Eur J Hum Genet 17: 1043-1049

Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter.

Treutlein J, Mühleisen TW, Frank J, Mattheisen M, Herms S, Ludwig KU, Treutlein T, Schmael C, Strohmaier J, Böβhenz KV, Breuer R, Paul T, Witt SH, Schulze TG, Schlösser RG, Nenadic I, Sauer H, Becker T, Maier W, Cichon S, Nöthen MM, Rietschel M (2009), Schizophr Res 111(1-3):123-30

The DISC locus and schizophrenia - Evidence from an association study in a central European sample and from a meta-analysis across different European populations.

Schumacher J, Laje G, Abou Jamra R, Becker T, Mühleisen TW, Vasilescu C, Mattheisen M, Herms S, Hoffmann P, Hillmer AM, Georgi A, Herold C, Schulze TG, Propping P, Rietschel M, McMahon FJ, Nöthen MM, Cichon S (2009), Hum Mol Genet 18:2719-27

A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation.

El-Maarri O, Kareta MS, Mikeska T, Becker T, Diaz-Lacava A, Junen J, Nüsgen N, Behne F, Wienker T, Waha A, Oldenburg J, Chédin F (2009), Hum Mol Genet 18(10):1755-68

Evaluation of Potential Power Gain with Imputed Genotypes in Genome-Wide Association Studies

Becker T, Flaquer A, Brockschmidt FF, Herold C, Steffens M (2009), Hum Hered 68:23-34

GENESTAT: an information portal for design and analysis of genetic association studies.

Ripatti S, Becker T, Bickeböller H, Dominicus A, Fischer C, Humphreys K, Jonasdottir G, Moreau Y, Olsson M, Ploner A, Sheehan N, Van Steen K, Baur M, van Duijn C, Palmgren J (2009), Eur J Hum Genet 17:533-536

Diabetes Genetics Consortium Three microsatellites from the T1DGC MHC data set show highly significant association with type 1 diabetes, independent of the HLA-DRB1, -DQA1 and -DQB1 genes.

Eike MC, Humphreys K, Becker T, Olsson M, Lie BA (2009), Diabetes Obes Metab. 2009 Feb;11 Suppl 1:17-24.

Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B.

Eike MC, Becker T, Humphreys K, Olsson M, Lie BA (2009), Genes Immun. 2009 Jan;10(1):56-67

Genetic association analysis with FAMHAP: a major program update.

Herold C, Becker T (2009), Bioinformatics 25: 134-136

Expression levels of FAS are regulated through an evolutionary conserved element in intron 2, which modulates cystic fibrosis disease severity.

Kumar V, Becker T, Jansen S, van Barneveld A, Boztug K, Wölfl S, Tümmler B, Stanke F (2008), Genes Immun 9:689-96

Susceptibility variants for male-pattern baldness on chromosome 20p11.

Hillmer AM, Brockschmidt FF, Hanneken S, Eigelshoven S, Steffens M, Flaquer A, Herms S, Becker T, Kortüm AK, Nyholt DR, Zhao ZZ, Montgomery GW, Martin NG, Mühleisen TW, Alblas MA, Moebus S, Jöckel KH, Bröcker-Preuss M, Erbel R, Reinartz R, Betz RC, Cichon S, Propping P, Baur MP, Wienker TF, Kruse R, Nöthen MM (2008), Nat Genet 40:1279-81

Unipolar depression and hippocampal volume: Impact of DNA sequence variants of the glucocorticoid receptor gene.

Zobel A, Jessen F, von Widdern O, Schuhmacher A, Höfels S, Metten M, Rietschel M, Scheef L, Block W, Becker T, Schild HH, Maier W, Schwab SG (2008), Am J Med Genet B Neuropsychiatr Genet 5;147B(6):836-43

Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder.

Abou Jamra R, Gobina CM, Becker T, Georgi A, Schulze TG, Schmael C, Cichon S, Propping P, Rietschel M, Nöthen MM, Schumacher J (2008), Psychiatr Genet 18:199-203

Testing association in the presence of linkage using the GRE and multiple markers.

Jonasdottir G, Becker T, Humphreys K, Palmgren J (2008), Genet Epidemiol 32: 425-33

Genetic variation of the FAT gene at 4q35 is associated with bipolar affective disorder.

Abou Jamra R, Becker T, Georgi A, Feulner T, Schumacher J, Stromaier J, Schirmbeck F, Schulze TG, Propping P, Rietschel M, Nothen MM, Cichon S (2008), Mol Psychiatry 13: 277-84

Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males.

El-Maarri O, Becker T, Junen J, Manzoor SS, Diaz-Lacava A, Schwaab R, Wienker T, Oldenburg J (2007), Hum Genet 122:505-514

Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample.

Georgi A, Jamra RA, Klein K, Villela AW, Schumacher J, Becker T, Paul T, Schmael C, Hofels S, Klopp N, Illig T, Propping P, Cichon S, Nothen MM, Schulze TG, Rietschel M (2007), Psychiatr Genet 17:308-310.

Transmission ratio distortion and maternal effects confound the analysis of modulators of cystic fibrosis disease severity on 19q13.

Becker T, Jansen S, Tamm S, Wienker TF, Tummler B, Stanke F (2007), Eur J Hum Genet 15:774-778

No association between a common haplotype of the 6 and 10-repeat alleles in intron 8 and the 3'UTR of the DAT1 gene and adult attention deficit hyperactivity disorder.

Bruggemann D, Sobanski E, Alm B, Schubert T, Schmalzried H, Phillipsen A, Breen G, Becker T, Georgi A, Skowronek MH, Schulze TG, Treutlein J, Rietschel M  (2007), Psychiatr Genet17: 121

No association between the serine racemase gene (SRR) and bipolar disorder in a German case-control sample.

Schirmbeck F, Georgi A, Strohmaier J, Schmael C, Knorr C, Jamra RA, Schumacher J, Becker T, Klopp N, Illig T, Wulf M, Schwarz M, Maier W, Propping P, Cichon S, Nothen MM, Schulze TG, Rietschel M (2007), Psychiatr Genet 17:127

Mitochondrial translation initiation factor 3 gene polymorphism associated with Parkinson's disease.

Abahuni N, Gispert S, Bauer P, Riess O, Kruger R, Becker T, Auburger G (2007), Neurosci Lett 414:126-129

No evidence for an association between variants at the gamma-amino-n-butyric acid type A receptor beta2 locus and schizophrenia.

Jamra RA, Becker T, Klopp N, Dahdouh F, Schulze TG, Gross M, Deschner M, Schmal C, Illig T, Rietschel M, Propping P, Cichon S, Nothen MM, Schumacher J (2007), Psychiatr Genet 17:43-45.

Investigation of the functional variant c.-169T > C of the Fc receptor-like 3 (FCRL3) gene in alopecia areata.

Schafer N, Blaumeiser B, Becker T, Freudenberg-Hua Y, Hanneken S, Eigelshoven S, Schmael C, Lambert J, De Weert J, Kruse R, Nothen MM, Betz RC (2007), Int J Immunogenet 33:393-395

No association between genetic variants at the ASCT1 gene and schizophrenia or bipolar disorder in a German sample.

Skowronek MH, Georgi A, Abou Jamra R, Schumacher J, Becker T, Schmael C, Paul T, Deschner M, Hofels S, Wulff M, Schwarz M, Klopp N, Illig T, Propping P, Cichon S, Nothen MM, Schulze TG, Rietschel M (2006), Psychiatr Genet 16:233-234

Detection of Parent-of-Origin Effects Using Haplotype Analysis.

Becker T, Baur MP, Knapp M (2006), Hum Hered 62:64-76

Family-based association study of the MTHFR polymorphism C677T in the bladder-exstrophy-epispadias-complex.

Reutter H, Becker T, Ludwig M, Schafer N, Detlefsen B, Beaudoin S, Fisch M, Ebert AK, Rosch W, Nothen MM, Boemers TM, Betz RC (2006), Am J Med Genet A 140: 2506-2509

No association between genetic variants at the GRIN1 gene and bipolar disorder in a German sample.

Georgi A, Jamra RA, Schumacher J, Becker T, Schmael C, Deschner M, Hofels S, Wulff M, Schwarz M, Klopp N, Illig T, Propping P, Cichon S, Nothen MM, Rietschel M, Schulze TG (2006), Psychiatr Genet 16:183-184

Association study between genetic variants at the PIP5K2A gene locus and schizophrenia and bipolar affective disorder.

Jamra RA, Klein K, Villela AW, Becker T, Schulze TG, Schmael C, Deschner M, Klopp N, Illig T, Propping P, Cichon S, Rietschel M, Nothen MM, Schumacher J  (2006), Am J Med Genet B Neuropsychiatr Genet 141:663-665

Evidence for association of DNA sequence variants in the phosphatidylinositol-4-phosphate 5-kinase IIalpha gene (PIP5K2A) with schizophrenia.

Schwab SG, Knapp M, Sklar P, Eckstein GN, Sewekow C, Borrmann-Hassenbach M, Albus M, Becker T, Hallmayer JF, Lerer B, Maier W, Wildenauer DB  (2006), Mol Psychiatry 11:837-846

A common origin of the 4143insA ADAMTS13 mutation.

Schneppenheim R, Kremer Hovinga JA, Becker T, Budde U, Karpman D, Brockhaus W, Hrachovinova I, Korczowski B, Oyen F, Rittich S, von Rosen J, Tjonnfjord GE, Pimanda JE, Wienker TF, Lammle B (2006), Thromb Haemost 96:3-6

Investigation of the p.Ser278Arg polymorphism of the autoimmune regulator (AIRE) gene in alopecia areata.

Pforr J, Blaumeiser B, Becker T, Freudenberg-Hua Y, Hanneken S, Eigelshoven S, Cuyt I, De Weert J, Lambert J, Kruse R, Nothen MM, Betz RC (2006), Tissue Antigens 68:58-61

No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia.

Jamra RA, Villela AW, Klein K, Becker T, Schulze TG, Schmael C, Deschner M, Klopp N, Illig T, Propping P, Cichon S, Rietschel M, Nothen MM, Schumacher J  (2006), Psychiatr Genet 16

Association of BRD2 polymorphisms with photoparoxysmal response.

Lorenz S, Taylor KP, Gehrmann A, Becker T, Muhle H, Gresch M, Tauer U, Sander T, Stephani U (2006), Neurosci Lett 400:135-9

Haplotype-based systematic association studies of ATP1A2 in migraine with aura.

Netzer C, Todt U, Heinze A, Freudenberg J, Zumbroich V, Becker T, Goebel I, Ohlraun S, Goebel H, Kubisch C  (2006), Am J Med Genet B Neuropsychiatr Genet 141:257-60

The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis.

Stanke F, Becker T, Cuppens H, Kumar V, Cassiman JJ, Jansen S, Radojkovic D, Siebert B, Yarden J, Ussery DW, Wienker TF, Tummler B (2006), Hum Genet 19:331-43

Identification of probable genotyping errors by consideration of haplotypes.

Becker T, Valentonyte R, Croucher PJP, Strauch K, Schreiber S, Hampe J, Knapp M (2006), Eur J Hum Genet 14: 450-8.

Candidate gene analysis of the succinic semialdehyde gene (ALDH5A1) in patients with idiopathic generalized epilepsy and photosenistivity.

Lorenz S, Heils A, Taylor KP, Gehrmann A, Muhle A, Gresch M, Becker T, Tauer U, Stephani U, Sander T (2006), Neurosci Lett 397:234-9

Genetic modifiers in cystic fibrosis.

Stanke F, Tuemmler B, Becker T (2006), N Engl J Med 354: 88-90

Multiple testing in the context of haplotype analysis revisited: application to case-control data.

Becker T, Cichon S, Jönson E, Knapp M (2005), Ann Hum Genet 69: 747-756

Genotype-Phenotype Studies in Bipolar Disorder Showing Association between DAOA/G30 Locus and Persecutory Delusions: A First Step Toward a Molecular Genetic Classification of Psychiatric Phenotypes.

Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidmann V, Kovalenko S, Jamra RA, Becker T, Leszczynska-Rodziewicz A, Hauser J, Illig T, Klopp N, Wellek S, Cichon S, Henn FA, McMahon FJ, Maier W, Propping P, Noethen MM, Rietschel M (2005), Am J Psychiatry 162:2101-2108

Haplotype Interaction Analysis of Unlinked Regions.

Becker T, Schumacher J, Cichon S, Baur MP, Knapp M (2005), Genet Epidemiol 29: 313-322

No evidence for an association between variants at the proline dehydrogenase locus and schizophrenia or bipolar affective disorder.

Jamra RA, Schumacher J, Becker T, Dahdouh F, Ohlraun S, Suliman H, Schulze TG, Tullius M, Kovalenko S, Maier W, Rietschel M, Propping P, Nothen MM, Cichon S (2005), Psychiatr Genet 15:195-198.

Impact of missing genotype data on Monte-carlo simulation based haplotype analysis.

Becker T, Knapp M (2005), Hum Hered 59:185-189

Evidence for a Relationship Between Genetic Variants at the Brain-Derived Neurotrophic Factor (BDNF) Locus and Major Depression.

Schumacher J, Jamra RA, Becker T, Ohlraun S, Klopp N, Binder EB, Schulze TG, Deschner M, Schmal C, Hofels S, Zobel A, Illig T, Propping P, Holsboer F, Rietschel M, Nothen MM, Cichon S  (2005), Biol Psychiatry 58:307-14

Association Between the Putative Functional ZDHHC8 Single Nucleotide Polymorphism rs175174 and Schizophrenia in Large European Samples.

Glaser B, Schumacher J, Williams HJ, Jamra RA, Ianakiev N, Milev R, Ohlraun S, Schulze TG, Czerski PM, Hauser J, Jonsson EG, Sedvall GC, Klopp N, Illig T, Becker T, Propping P, Williams NM, Cichon S, Kirov G, Rietschel M, Murphy KC, O'donovan MC, Nothen MM, Owen MJ (2005), Biol Psychiatry 58:78-80

Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia.

Hillmer AF, Hanneken S, Ritzmann S, Becker T, Freudenberg J, Brockschmidt FF, Flaquer A, Freudenberg-Hua Y, Abou Jamra R, Metzen C, Heyn U, Schweiger N, Betz RC, Blaumeiser B, Hampe J, Schreiber S, Schulze TG, Hennies HC, Schumacher J, Propping P, Ruzicka T, Cichon S, Wienker TF, Kruse R, Nöthen MM (2005), Am J Hum Genet 77:140-148

A family-based and case-control association study of trace amine receptor genes on chromosome 6q23 in bipolar affective disorder.

Abou Jamra R, Sircar I, Becker T, Freudenberg-Hua Y, Ohlraun S, Freudenberg J, Brockschmidt F, Schulze TG, Gross M, Spira F, Deschner M, Schmal C, Maier W, Propping P, Rietschel M, Cichon S, Nothen MM, Schumacher J (2005), Mol Psychiatry 10:618-620

Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: Preferential transmission of the MAO-A 941G allele to affected children.

Domschke K, Sheehan K, Lowe N, Kirley A, Mullins C, O'Sullivan R, Freitag C, Becker T, Conroy J, Fitzgerald M, Gill M, Hawi Z  (2005), Am J Med Genet B Neuropsychiatr Genet 134:110-114.

The power of sample size and homogenous sampling: Association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder.

Hoefgen B, Schulze TG, Ohlraun S, von Widdern O, Hofels S, Gross M, Heidmann V, Kovalenko S, Eckermann A, Kolsch H, Metten M, Zobel A, Becker T, Nothen MM, Propping P, Heun R, Maier W, Rietschel M. (2005), Biol Psychiatry 57:247-51.

Investigation of the DAOA/G30 locus in panic disorder.

Schumacher J, Abou Jamra R, Becker T, Klopp N, Franke P, Jacob C, Sand P, Fritze J, Ohlraun S, Schulze TG, Rietschel M, Illig T, Propping P, Cichon S, Deckert J, Nöthen MM (2005), Mol Psychiatry 10:428-429

A powerful strategy to account for multiple testing in the context of haplotype analysis.

Becker T, Knapp M (2004), Am J Hum Genet 75:561-70

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.

Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG, Tullius M, Gross MM, Jones L, Krastev S, Nikolov I, Hamshere M, Jones I, Czerski PM, Leszczynska-Rodziewicz A, Kapelski P, Bogaert AV, Illig T, Hauser J, Maier W, Berrettini W, Byerley W, Coryell W, Gershon ES, Kelsoe JR, McInnis MG, Murphy DL, Nurnberger JI, Reich T, Scheftner W, O'Donovan MC, Propping P, Owen MJ, Rietschel M, Nöthen MM, McMahon FJ, Craddock N (2004), Nat Genet 36:783-4; author reply 784-5. (Letter to the Editor)

Maximum-Likelihood Estimation of Haplotype Frequencies in Nuclear Families.

Becker T, Knapp M (2004), Genet Epidemiol 27: 21-32.

Impact of Genotyping Errors on Type I Error Rate of the Haplotype-Sharing Transmission/Disequilibrium Test (HS-TDT).

Knapp M, Becker T (2004), Am J Hum Genet 74:589-591. (Letter to the Editor)

Examination of G72 and D-amino acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder.

Schumacher J, Jamra RA, Freudenberg J, Becker T, Ohlraun S, Otte AC, Tullius M, Kovalenko S, Bogaert AV, Maier W, Rietschel M, Propping P, Nöthen MM, Cichon S (2004), Mol Psychiatry 9:203-207.

Genotypic association of exonic LGI4 polymorphisms and childhood absence epilepsy.

Gu W, Sander T, Becker T, Steinlein OK (2004), Neurogenetics 5:41-44

The DTNBP1 (Dysbindin) Gene Contributes to Schizophrenia, Depending on Family History of the Disease.

Van Den Bogaert A, Schumacher J, Schulze TG, Otte AC, Ohlraun S, Kovalenko S, Becker T, Freudenberg J, Jönsson EG, Mattila-Evenden M, Sedvall GC, Czerski PM, Kapelski P, Hauser J, Maier W, Rietschel M, Propping P, Nöthen MM, Cichon S (2003), Am J Hum Genet 73:1438-1443.

No evidence for DUP25 in patients with panic disorder using a quantitative real-time PCR approach.

Schumacher J, Otte AC, Becker T, Sun Y, Wienker TF, Wirth B, Franke P, Abou Jamra R, Propping P, Deckert J, Nöthen MM, Cichon S (2003), Hum Genet 114:115-117.

Family-Based Association Analysis with Tightly Linked Markers.

Knapp M, Becker T (2003), Hum Hered 56:2-9.

Comment on "The Impact of genotyping error on haplotype reconstruction and frequency estimation".

Becker T, Knapp M (2003), Eur J Hum Genet 11:637. (Letter to the Editor)

Efficiency of haplotype frequency estimation when nuclear family information is included.

Becker T, Knapp M (2002), Hum Hered 54:45-53.