Publikationen 2012
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid Beta formation.
Leuner K, Schütt T, Kurz C, Eckert SH, Schiller C, Occhipinti A, Mai S, Jendrach M, Eckert GP, Kruse SE, Palmiter RD, Brandt U, Dröse S, Wittig I, Willem M, Haass C, Reichert AS, Müller WE. Antioxid Redox Signal. 2012 Jun 15;16(12):1421-33. Epub 2012 Feb 28.
Methylmalonate impairs mitochondrial respiration supported by NADH-linked substrates: Involvement of mitochondrial glutamate metabolism.
Melo DR, Mirandola SR, Assunção NA, Castilho RF. J Neurosci Res. 2012 Jun;90(6):1190-9. doi: 10.1002/jnr.23020. Epub 2012 Feb 20.
Cellular prion protein mediates toxic signaling of amyloid Beta.
Resenberger UK, Winklhofer KF, Tatzelt J. Neurodegener Dis. 2012;10(1-4):298-300. Epub 2011 Dec 9.
Linking Amyloid-β and Tau: Amyloid-β Induced Synaptic Dysfunction via Local Wreckage of the Neuronal Cytoskeleton.
Zempel H, Mandelkow EM. Neurodegener Dis. 2012;10(1-4):64-72. Epub 2011 Dec 7.
People with dementia in acute hospitals : Literature review of prevalence and reasons for hospital admission.[Menschen mit Demenz im Akutkrankenhaus - Literaturübersicht zu Prävalenz und Einweisungsgründen.]
Pinkert C, Holle B. Z Gerontol Geriatr. 2012 Apr 28. [Epub ahead of print]
Associated factors of different nutrition indicators in German nursing home residents : Comparative results of a multicenter cross-sectional study.
Palm R, Reuther S, Bartholomeyczik S. Z Gerontol Geriatr. 2012 Apr 27. [Epub ahead of print]
Follow-Up Study of the First Genome-Wide Association Scan in Alopecia Areata: IL13 and KIAA0350 as Susceptibility Loci Supported with Genome-Wide Significance.
Jagielska D, Redler S, Brockschmidt FF, Herold C, Pasternack SM, Garcia Bartels N, Hanneken S, Eigelshoven S, Refke M, Barth S, Giehl KA, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Blume-Peytavi U, Becker T, Nöthen MM, Betz RC. J Invest Dermatol. 2012 Apr 26. doi: 10.1038/jid.2012.129. [Epub ahead of print]
Dietary intakes of berries and flavonoids in relation to cognitive decline.
Devore EE, Kang JH, Breteler MM, Grodstein F. Ann Neurol. 2012 Apr 26. doi: 10.1002/ana.23594. [Epub ahead of print]
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.
Van der Jeugd A, Hochgräfe K, Ahmed T, Decker JM, Sydow A, Hofmann A, Wu D, Messing L, Balschun D, D'Hooge R, Mandelkow EM. Acta Neuropathol. 2012 Apr 25. [Epub ahead of print]
ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice
Schumacher T, Krohn M, Hofrichter J, Lange C, Stenzel J, Steffen J, Dunkelmann T, Paarmann K, Fröhlich C, Uecker A, Plath AS, Sommer A, Brüning T, Heinze HJ, Pahnke J. PLoS One. 2012;7(4):e35613. Epub 2012 Apr 24.
DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder.
Håvik B, Degenhardt FA, Johansson S, Fernandes CP, Hinney A, Scherag A, Lybæk H, Djurovic S, Christoforou A, Ersland KM, Giddaluru S, O'Donovan MC, Owen MJ, Craddock N, Mühleisen TW, Mattheisen M, Schimmelmann BG, Renner T, Warnke A, Herpertz-Dahlmann B, Sinzig J, Albayrak O, Rietschel M, Nöthen MM, Bramham CR, Werge T, Hebebrand J, Haavik J, Andreassen OA, Cichon S, Steen VM, Le Hellard S. PLoS One. 2012;7(4):e35424. Epub 2012 Apr 23.
Community-dwelling persons with dementia: What do they need? What do they demand? What do they do? A systematic review on the subjective experiences of persons with dementia.
von Kutzleben M, Schmid W, Halek M, Holle B, Bartholomeyczik S. Aging Ment Health. 2012 Apr;16(3):378-90. Epub 2012 Jan 18.
Replication Study and Meta-Analysis in European Samples Supports Association of the 3p21.1 Locus with Bipolar Disorder.
Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Babadjanova G, Abramova LI, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, Clair DS, Gustafsson O, Melle I, Pietiläinen OP, Ruggeri M, Tosato S, Werge T, Ophoff RA; GROUP Consortium, Rujescu D, Børglum AD, Mors O, Mortensen PB, Demontis D, Hollegaard MV, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Rubino IA, Golimbet V, Kiemeney LA, van den Berg LH, Franke B, Jönsson EG, Farmer A, Stefansson H, Stefansson K, Collier DA. Biol Psychiatry. 2012 May 4. [Epub ahead of print]
D90A-SOD1 ALS mimicking monoclonal gammopathy-associated ALS.
Synofzik M, Hagen JM, Biskup S, Schöls L. Amyotroph Lateral Scler. 2012 May;13(3):326-7. Epub 2012 Mar 13.
Cytosolic Ca2+ regulates the energization of isolated brain mitochondria by formation of pyruvate through the malate-aspartate shuttle.
Gellerich FN, Gizatullina Z, Trumbekaite S, Korzeniewski B, Gaynutdinov T, Seppet E, Vielhaber S, Heinze HJ, Striggow F. Biochem J. 2012 May 1;443(3):747-55.
Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified.
Redler S, Tazi-Ahnini R, Drichel D, Birch MP, Brockschmidt FF, Dobson K, Giehl KA, Refke M, Kluck N, Kruse R, Lutz G, Wolff H, Böhm M, Becker T, Nöthen MM, Betz RC, Messenger A. Exp Dermatol. 2012 May;21(5):390-393. doi: 10.1111/j.1600-0625.2012.01469.x.
Atrophy of the cholinergic basal forebrain over the adult age range and in early stages of Alzheimer's disease
M Grothe, H Heinsen, SJ Teipel; Biol Psychiatry. 2012 May 1;71(9):805-13. Epub 2011 Aug 4.
Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample.
Degenhardt F, Priebe L, Herms S, Mattheisen M, Mühleisen TW, Meier S, Moebus S, Strohmaier J, Groß M, Breuer R, Lange C, Hoffmann P, Meyer-Lindenberg A, Heinz A, Walter H, Lucae S, Wolf C, Müller-Myhsok B, Holsboer F, Maier W, Rietschel M, Nöthen MM, Cichon S. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr;159B(3):263-273. doi: 10.1002/ajmg.b.32034. Epub 2012 Feb 17.
The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.
Butler EK, Voigt A, Lutz AK, Toegel JP, Gerhardt E, Karsten P, Falkenburger B, Reinartz A, Winklhofer KF, Schulz JB. PLoS Genet. 2012 Feb;8(2):e1002488. Epub 2012 Feb 2.
N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation.
Schlenzig D, Rönicke R, Cynis H, Ludwig HH, Scheel E, Reymann K, Saido T, Hause G, Schilling S, Demuth HU. J Neurochem. 2012 Jun;121(5):774-84. doi: 10.1111/j.1471-4159.2012.07707.x. Epub 2012 Mar 28.
MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults.
Wefers B, Hitz C, Hölter SM, Trümbach D, Hansen J, Weber P, Pütz B, Deussing JM, de Angelis MH, Roenneberg T, Zheng F, Alzheimer C, Silva A, Wurst W, Kühn R. PLoS One. 2012;7(4):e35035. Epub 2012 Apr 18.
Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success.
Balbach ST, Esteves TC, Houghton FD, Siatkowski M, Pfeiffer MJ, Tsurumi C, Kanzler B, Fuellen G, Boiani M. PLoS One. 2012;7(4):e35322. Epub 2012 Apr 18.
For gut's sake: NLRC4 inflammasomes distinguish friend from foe.
Franklin BS, Latz E. Nat Immunol. 2012 Apr 18;13(5):429-31. doi: 10.1038/ni.2289.
Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis.
Scheffler K, Krohn M, Dunkelmann T, Stenzel J, Miroux B, Ibrahim S, von Bohlen und Halbach O, Heinze HJ, Walker LC und Gsponer JA, Pahnke J. Acta Neuropathologica. 2012 Apr 18. doi: 10.1007/s00401-012-0980-x [Epub ahead of print]
Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation.
Azimzadeh O, Scherthan H, Yentrapalli R, Barjaktarovic Z, Ueffing M, Conrad M, Neff F, Calzada-Wack J, Aubele M, Buske C, Atkinson MJ, Hauck SM, Tapio S. J Proteomics. 2012 Apr 18;75(8):2384-95. Epub 2012 Feb 23.
Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating.
Quednow BB, Brinkmeyer J, Mobascher A, Nothnagel M, Musso F, Gründer G, Savary N, Petrovsky N, Frommann I, Lennertz L, Spreckelmeyer KN, Wienker TF, Dahmen N, Thuerauf N, Clepce M, Kiefer F, Majic T, Mössner R, Maier W, Gallinat J, Diaz-Lacava A, Toliat MR, Thiele H, Nürnberg P, Wagner M, Winterer G. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6271-6. Epub 2012 Mar 26.
Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: A European multicenter study.
Hammer C, Cichon S, Mühleisen TW, Haenisch B, Degenhardt F, Mattheisen M, Breuer R, Witt SH, Strohmaier J, Oruc L, Rivas F, Babadjanova G, Grigoroiu-Serbanescu M, Hauser J, Röth R, Rappold G, Rietschel M, Nöthen MM, Niesler B. Translational Psychiatry (2012) 2, e103; doi:10.1038/tp.2012.30
Cognitive impairment in primary ambulatory health care: pharmacotherapy and the use of potentially inappropriate medicine.
Fiss T, Thyrian JR, Fendrich K, van den Berg N, Hoffmann W. Int J Geriatr Psychiatry. 2012 Apr 16. doi: 10.1002/gps.3806. [Epub ahead of print]
Epigenetic alteration of the dopamine transporter gene in alcohol-dependent patients is associated with age.
Nieratschker V, Grosshans M, Frank J, Strohmaier J, von der Goltz C, El-Maarri O, Witt SH, Cichon S, Nöthen MM, Kiefer F, Rietschel M. Addict Biol. 2012 Apr 16. doi: 10.1111/j.1369-1600.2012.00459.x. [Epub ahead of print]
Neuroimaging: Current role in detecting pre-motor Parkinson's disease.
Godau J, Hussl A, Lolekha P, Stoessl AJ, Seppi K. Mov Disord. 2012 Apr 15;27(5):634-43. doi: 10.1002/mds.24976.
Can we define "pre-motor" Parkinson's disease?
Berg D, Poewe W. Mov Disord. 2012 Apr 15;27(5):595-6. doi: 10.1002/mds.24995.
Common variants at 6q22 and 17q21 are associated with intracranial volume.
the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT Jr, Niessen WJ, Destefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, Pourcain BS, Timpson NJ, Smith GD, Sovio U, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, Decarli C; Early Growth Genetics (EGG) Consortium, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Coin L, Davis OS, Elliott P, Flexeder C, Frayling T, Gaillard R, Groen-Blokhuis M, Goh LK, Haworth CM, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Jan Hottenga J, Horikoshi M, Huikari V, Hypponen E, Kilpeläinen TO, Kirin M, Kowgier M, Lakka HM, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, Panoutsopoulou K, Pararajasingham J, Rodriguez A, Salem RM, Sebert S, Siitonen N, Strachan DP, Teo YY, Valcárcel B, Willemsen G, Zeggini E, Boomsma DI, Cooper C, Gillman M, Hocher B, Lakka TA, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Price TS, Power C, Raitakari OT, Saw SM, Scherag A, Simell O, Sørensen TI, Wilson JF. Nat Genet. 2012 Apr 15;44(5):539-544. doi: 10.1038/ng.2245.
Common variants at 12q14 and 12q24 are associated with hippocampal volume.
Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, Bis JC, Decarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, Destefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Nat Genet. 2012 Apr 15;44(5):545-551. doi: 10.1038/ng.2237.
Common variants at 12q15 and 12q24 are associated with infant head circumference.
Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bønnelykke K, Buxton JL, Charoen P, Chawes BL, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Müller-Nurasyid M, O'Reilly PF, Prokopenko I, Rivadeneira F, Steegers EA, Sunyer J, Tiesler C, Yaghootkar H; The Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium, Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Coker LH, Longstreth WT Jr, Niessen WJ, Destefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, Decarli C, Breteler MM, Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley TH Jr, Seshadri S, Smith AV, Vernooij MW; Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Ang W, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Elliott P, Evans DM, Frayling T, Freathy RM, Gaillard R, Groen-Blokhuis M, Guxens M, Hadley D, Hottenga JJ, Huikari V, Hypponen E, Kaakinen M, Kowgier M, Lawlor DA, Lewin A, Lindgren C, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Nivard M, O'Reilly PF, Palmer LJ, Prokopenko I, Rodriguez A, Sebert S, Sovio U, St Pourcain B, Standl M, Strachan DP, Sunyer J, Taal HR, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Boomsma DI, Estivill X, Grant SF, Hakonarson H, Hattersley AT, Heinrich J, Jaddoe VW, Jarvelin MR, McCarthy MI, Pennell CE, Power C, Timpson NJ, Widen E, Blakemore AI, Chiavacci RM, Feenstra B, Fernandez-Banet J, Grant SF, Hartikainen AL, van der Heijden AJ, Iñiguez C, Lathrop M, McArdle WL, Mølgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann HE, Vissing NH, Decarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin MR, Jaddoe VW; Early Growth Genetics (EGG) Consortium, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Davis OS, Elliott P, Evans DM, Feenstra B, Flexeder C, Frayling T, Freathy RM, Gaillard R, Geller F, Groen-Blokhuis M, Goh LK, Guxens M, Haworth CM, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Hottenga JJ, Horikoshi M, Huikari V, Hypponen E, Iñiguez C, Kaakinen M, Kilpeläinen TO, Kirin M, Kowgier M, Lakka HM, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, O'Reilly PF, Palmer LJ, Panoutsopoulou K, Pararajasingham J, Prokopenko I, Rodriguez A, Salem RM, Sebert S, Siitonen N, Sovio U, St Pourcain B, Strachan DP, Sunyer J, Taal HR, Teo YY, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Zeggini E, Boomsma DI, Cooper C, Estivill X, Gillman M, Grant SF, Hakonarson H, Hattersley AT, Heinrich J, Hocher B, Jaddoe VW, Jarvelin MR, Lakka TA, McCarthy MI, Melbye M, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Pennell CE, Price TS, Power C, Raitakari OT, Saw SM, Scherag A, Simell O, Sørensen TI, Timpson NJ, Widen E, Wilson JF. Nat Genet. 2012 Apr 15;44(5):532-538. doi: 10.1038/ng.2238.
Identification of common variants associated with human hippocampal and intracranial volumes.
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann O, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; the Alzheimer's Disease Neuroimaging Initiative (ADNI); EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group (SYS), Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, Decarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM. Nat Genet. 2012 Apr 15;44(5):552-561. doi: 10.1038/ng.2250.
Tau's role in the developing brain: implications for intellectual disability.
Sapir T, Frotscher M, Levy T, Mandelkow EM, Reiner O. Hum Mol Genet. 2012 Apr 15;21(8):1681-92. Epub 2011 Dec 21.
Repeatable target localization for long-term in vivo imaging of mice with 2-photon microscopy.
Hefendehl JK, Milford D, Eicke D, Wegenast-Braun BM, Calhoun ME, Grathwohl SA, Jucker M, Liebig C. J Neurosci Methods. 2012 Apr 15;205(2):357-63. Epub 2011 Nov 6.
Characterizing POLG Ataxia: Clinics, Electrophysiology and Imaging.
Synofzik M, Srulijes K, Godau, J, Berg D, Schöls L. Cerebellum. 2012 Apr 12 [Epub ahead of print], DOI: 10.1007/s12311-012-0378-2
Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes.
Pedroso I, Lourdusamy A, Rietschel M, Nöthen MM, Cichon S, McGuffin P, Al-Chalabi A, Barnes MR, Breen G. Biol Psychiatry. 2012 Apr 12. [Epub ahead of print]
Calcium-Dependent Dephosphorylation of the Histone Chaperone DAXX Regulates H3.3 Loading and Transcription upon Neuronal Activation.
Michod D, Bartesaghi S, Khelifi A, Bellodi C, Berliocchi L, Nicotera P, Salomoni P. Neuron. 2012 Apr 12;74(1):122-35.
HDAC1 Regulates Fear Extinction in Mice.
Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle I, Kügler S, Fischer A, Sananbenesi F. J Neurosci. 2012 Apr 11;32(15):5062-5073.
Memantine effects measured with the Relevant Outcome Scale for Alzheimer's disease in an open-label, single-arm, multicenter clinical study.
Holthoff V, Ferris S, Gauthier S, Ihl R, Robert P, Winblad B, Sternberg K, Tennigkeit F; The ROSA Study Group. Int J Geriatr Psychiatry. 2012 Apr 11. doi: 10.1002/gps.3805. [Epub ahead of print]
6-Hydroxydopamine leads to T2 hyperintensity, decreased claudin-3 immunoreactivity and altered aquaporin 4 expression in the striatum.
Wachter B, Schürger S, Schmid A, Gröger A, Sadler R, Speidel A, Rolinger J, Pichler BJ, Berg D, Wagner HJ, von Ameln-Mayerhofer A, Küppers E. Behav Brain Res. 2012 Apr 10;232(1):148-158. [Epub ahead of print]
Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder.
Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, Breuer R, Meier S, Hoffmann P; GROUP Investigators, Rivandeneira F, Hofman A, Uitterlinden AG, Moebus S, Gieger C, Emeny R, Ladwig KH, Wichmann HE, Schwarz M, Kammerer-Ciernioch J, Schlösser RG, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Lange C, Ophoff RA, Schulze TG, Rietschel M, Nöthen MM, Cichon S. Schizophr Res. 2012 Apr 10. [Epub ahead of print]
Rat embryonic fibroblasts improve reprogramming of human keratinocytes into induced pluripotent stem cells.
Linta L, Stockmann M, Kleinhans KN, Böckers A, Storch A, Zaehres H, Lin Q, Barbi G, Böckers TM, Kleger A, Liebau S. Stem Cells Dev. 2012 Apr 10;21(6):965-76. Epub 2011 Aug 5.
Two Different Binding Modes of α-Synuclein to Lipid Vesicles Depending on its Aggregation State.
Högen T, Levin J, Schmidt F, Caruana M, Vassallo N, Kretzschmar H, Bötzel K, Kamp F, Giese A. Biophysical Journal, Volume 102, Issue 7, 1646-1655, 4 April 2012. doi:10.1016/j.bpj.2012.01.059
The nuclear form of Glutathione Peroxidase 4 is associated with sperm nuclear matrix and is required for proper paternal chromatin decondensation at fertilization.
Puglisi R, Maccari I, Pipolo S, Conrad M, Mangia F, Boitani C. (2011), J Cell Physiol. 2012 Apr;227(4):1420-7. doi: 10.1002/jcp.22857.
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.
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Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database.
Lill CM, Roehr JT, McQueen MB, Kavvoura FK, Bagade S, Schjeide BM, Schjeide LM, Meissner E, Zauft U, Allen NC, Liu T, Schilling M, Anderson KJ, Beecham G, Berg D, Biernacka JM, Brice A, Destefano AL, Do CB, Eriksson N, Factor SA, Farrer MJ, Foroud T, Gasser T, Hamza T, Hardy JA, Heutink P, Hill-Burns EM, Klein C, Latourelle JC, Maraganore DM, Martin ER, Martinez M, Myers RH, Nalls MA, Pankratz N, Payami H, Satake W, Scott WK, Sharma M, Singleton AB, Stefansson K, Toda T, Tung JY, Vance J, Wood NW, Zabetian CP; 23andMe, The Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium; The International Parkinson's Disease Genomics Consortium (IPDGC); The Parkinson's Disease GWAS Consortium; The Wellcome Trust Case Control Consortium 2 (WTCCC2), Young P, Tanzi RE, Khoury MJ, Zipp F, Lehrach H, Ioannidis JP, Bertram L. PLoS Genet. 2012 Mar;8(3):e1002548. Epub 2012 Mar 15.
Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings.
Jacobi H, Hauser TK, Giunti P, Globas C, Bauer P, Schmitz-Hübsch T, Baliko L, Filla A, Mariotti C, Rakowicz M, Charles P, Ribai P, Szymanski S, Infante J, van de Warrenburg BP, Dürr A, Timmann D, Boesch S, Fancellu R, Rola R, Depondt C, Schöls L, Zdzienicka E, Kang JS, Ratzka S, Kremer B, Stephenson DA, Melegh B, Pandolfo M, du Montcel ST, Borkert J, Schulz JB, Klockgether T. Cerebellum. 2012 Mar;11(1):155-66.
IL-1, quo vadis?
Grebe A, Latz E. Atherosclerosis. 2012 Mar 29. [Epub ahead of print]
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Generation of a novel rodent model for DYT1 dystonia.
Grundmann K, Glöckle N, Martella G, Sciamanna G, Hauser TK, Yu L, Castaneda S, Pichler B, Fehrenbacher B, Schaller M, Nuscher B, Haass C, Hettich J, Yue Z, Nguyen HP, Pisani A, Riess O, Ott T. Neurobiol Dis. 2012 Mar 26. [Epub ahead of print]
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Motor signs in the prodromal phase of Parkinson's disease.
Maetzler W, Hausdorff JM. Mov Disord. 2012 Apr 15;27(5):627-33. doi: 10.1002/mds.24973. Epub 2012 Mar 21.
Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.
Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Bossù P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O'Donovan M, Valdivieso F, Caffara P, Scarpini E, Combarros O, Buée L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alpérovitch A, Lathrop M, Trégouët DA, Williams J, Amouyel P. Mol Psychiatry. 2012 Mar 20. doi: 10.1038/mp.2012.14. [Epub ahead of print]
Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells.
Thier M, Wörsdörfer P, Lakes YB, Gorris R, Herms S, Opitz T, Seiferling D, Quandel T, Hoffmann P, Nöthen MM, Brüstle O, Edenhofer F. Cell Stem Cell. 2012 Apr 6;10(4):473-9. Epub 2012 Mar 22.
Linkage-Disequilibrium-Based Binning Affects the Interpretation of GWASs.
Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nöthen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Jonassen I, Steen VM, Puntervoll P, Le Hellard S. Am J Hum Genet. 2012 Apr 6;90(4):727-33. Epub 2012 Mar 22.
Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors.
Han DW, Tapia N, Hermann A, Hemmer K, Höing S, Araúzo-Bravo MJ, Zaehres H, Wu G, Frank S, Moritz S, Greber B, Yang JH, Lee HT, Schwamborn JC, Storch A, Schöler HR. Cell Stem Cell. 2012 Apr 6;10(4):465-72. Epub 2012 Mar 22.
Ageing effects on path integration and landmark navigation.
Harris MA, Wolbers T. Hippocampus. 2012 Mar 19. doi: 10.1002/hipo.22011. [Epub ahead of print]
Medication review for dementia patients.[Medikationsreview in der psychiatrischen institutsambulanz.]
Jahns KP, Kilimann I, Ritter CA, Hoffmann W, Teipel SJ, Fiss T. Med Monatsschr Pharm. 2012 Mar;35(3):95-103.
NMDA-dependent mechanisms only affect the BOLD response in the rat dentate gyrus by modifying local signal processing.
Tiede R, Krautwald K, Fincke A, Angenstein F. J Cereb Blood Flow Metab. 2012 Mar;32(3):570-84. doi: 10.1038/jcbfm.2011.182. Epub 2011 Dec 14.
CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.
Poppensieker K, Otte DM, Schürmann B, Limmer A, Dresing P, Drews E, Schumak B, Klotz L, Raasch J, Mildner A, Waisman A, Scheu S, Knolle P, Förster I, Prinz M, Maier W, Zimmer A, Alferink J. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3897-902. Epub 2012 Feb 21.
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Pihlajamäki J, Lerin C, Kaminska D, Venesmaa S, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M, Patti ME. Cell Metab. 2012 Mar 7;15(3):267-9.
Integrated Genome-Wide Pathway Association Analysis with INTERSNP.
Herold C, Mattheisen M, Lacour A, Vaitsiakhovich T, Angisch M, Drichel D, Becker T. Hum Hered. 2012 Mar 7;73(2):63-72. [Epub ahead of print]
Neuroscience. Youth culture in the adult brain.
Kempermann G. Science. 2012 Mar 9;335(6073):1175-6.
Is pre-motor diagnosis possible?--The European experience.
Berg D. Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S195-8.
Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.
Glasl L, Kloos K, Giesert F, Roethig A, Di Benedetto B, Kühn R, Zhang J, Hafen U, Zerle J, Hofmann A, Hrabé de Angelis M, Winklhofer KF, Hölter SM, Vogt Weisenhorn DM, Wurst W. Exp Neurol. 2012 May;235(1):214-27. Epub 2012 Jan 11.
Microtubule Affinity-regulating Kinase 2 (MARK2) Turns on Phosphatase and Tensin Homolog (PTEN)-induced Kinase 1 (PINK1) at Thr-313, a Mutation Site in Parkinson Disease: EFFECTS ON MITOCHONDRIAL TRANSPORT.
Matenia D, Hempp C, Timm T, Eikhof A, Mandelkow EM. J Biol Chem. 2012 Mar 9;287(11):8174-86. Epub 2012 Jan 11.
Cooperative genome-wide analysis shows increased homozygosity in early onset Parkinson's disease.
Simón-Sánchez J, Kilarski LL, Nalls MA, Martinez M, Schulte C, Holmans P; International Parkinson's Disease Genomics Consortium; Wellcome Trust Case Control Consortium, Gasser T, Hardy J, Singleton AB, Wood NW, Brice A, Heutink P, Williams N, Morris HR. PLoS One. 2012;7(3):e28787. Epub 2012 Mar 12.
The amyloid state of proteins in human diseases.
Eisenberg D, Jucker M. Cell. 2012 Mar 16;148(6):1188-203.
Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis.
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Distinct patterns of cognitive impairment in multiple system atrophy patients of cerebellar and parkinsonian predominance
I. Frommanna, T. Schmitz-Hübsch, K. Hoenig, M. Minnerop, I. Daum, U. Wüllner, M. Wagner. Basal Ganglia 2012. doi: dx.doi.org/10.1016/j.baga.2012.02.001. Epub 2012 Mar 16.
Predictive value and reward in implicit classification learning.
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Hyperpolarization-activated cation current I(h) of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy.
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Weighting models and weighting factors.
G Vosgerau, M Synofzik; Conscious Cogn. 2012 Mar;21(1):55-8. Epub 2011 Oct 24.
The valence of action outcomes modulates the perception of one's actions.
C Wilke, M Synofzik, A Lindner; Conscious Cogn. 2012 Mar;21(1):18-29. Epub 2011 Jul 14.
Differentiation Efficiency of Induced Pluripotent Stem Cells Depends on the Number of Reprogramming Factors.
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Dopaminergic modulation of neural correlates of working memory in Parkinson’s Disease.
Kraft E, Binder E, Lulé D, Storch A, Gruber O. Article in Press. 2012 Mar. doi: 10.1016/j.baga.2012.01.003
Alpha-secretase cleavage of the amyloid precursor protein: proteolysis regulated by signaling pathways and protein trafficking.
Lichtenthaler SF. Curr Alzheimer Res. 2012 Feb 1;9(2):165-77.
The pain situation for residents of nursing homes : Results of a study in Münster.[Die Schmerzsituation von Bewohnern in der stationären Altenhilfe : Ergebnisse einer Studie in Münster.]
Osterbrink J, Hufnagel M, Kutschar P, Mitterlehner B, Krüger C, Bauer Z, Aschauer W, Weichbold M, Sirsch E, Drebenstedt C, Perrar KM, Ewers A. Schmerz. 2012 Feb;26(1):27-35.
Parkinson's disease. Perioperative management and anesthesia.[Morbus parkinson. Perioperatives management und anästhesie.]
Wüllner U, Standop J, Kaut O, Coenen V, Kalenka A, Wappler F. Anaesthesist. 2012 Feb;61(2):97-105.
Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease.
Wagner M, Wolf S, Reischies FM, Daerr M, Wolfsgruber S, Jessen F, Popp J, Maier W, Hüll M, Frölich L, Hampel H, Perneczky R, Peters O, Jahn H, Luckhaus C, Gertz HJ, Schröder J, Pantel J, Lewczuk P, Kornhuber J, Wiltfang J. Neurology. 2012 Feb 7;78(6):379-86. Epub 2012 Jan 11.
Movement-related theta rhythm in humans: coordinating self-directed hippocampal learning.
Kaplan R, Doeller CF, Barnes GR, Litvak V, Düzel E, Bandettini PA, Burgess N. PLoS Biol. 2012 Feb;10(2):e1001267. Epub 2012 Feb 28.
MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function.
Miller BH, Zeier Z, Xi L, Lanz TA, Deng S, Strathmann J, Willoughby D, Kenny PJ, Elsworth JD, Lawrence MS, Roth RH, Edbauer D, Kleiman RJ, Wahlestedt C. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3125-30. Epub 2012 Feb 6.
Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease.
Pilsl A, Winklhofer KF. Acta Neuropathol. 2012 Feb;123(2):173-88. Epub 2011 Nov 6.
Dopamine modulates memory consolidation of discrimination learning in the auditory cortex.
Schicknick H, Reichenbach N, Smalla KH, Scheich H, Gundelfinger ED, Tischmeyer W. Eur J Neurosci. 2012 Mar;35(5):763-74. doi: 10.1111/j.1460-9568.2012.07994.x. Epub 2012 Feb 17.
Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata.
Forstbauer LM, Brockschmidt FF, Moskvina V, Herold C, Redler S, Herzog A, Hillmer AM, Meesters C, Heilmann S, Albert F, Alblas M, Hanneken S, Eigelshoven S, Giehl KA, Jagielska D, Blume-Peytavi U, Garcia Bartels N, Kuhn J, Hennies HC, Goebeler M, Jung A, Peitsch WK, Kortüm AK, Moll I, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Kirov G, Becker T, Nöthen MM, Betz RC. Eur J Hum Genet. 2012 Mar;20(3):326-32. doi: 10.1038/ejhg.2011.185. Epub 2011 Oct 26.
Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats.
RF Rosen, JJ Fritz, J Dooyema, AF Cintron, T Hamaguchi, JJ Lah, H Levine 3rd, M Jucker, LC Walker; J Neurochem. 2012 Mar;120(5):660-666. doi: 10.1111/j.1471-4159.2011.07551.x. Epub 2011 Nov 18.
E-learning in family medicine in Germany - Update five years after founding the network [E-Learning in der Allgemeinmedizin (ELA) - Eine standortbestimmung in Deutschland fünf jahre nach der netzwerkgründung]
Schürer-Maly CC, Gummersbach E, Waldmann UM, Fischer MR, Abholz HH, Vollmar HC. Zeitschrift für Allgemeinmedizin Volume 88, Issue 2, February 2012, Pages 69-76. DOI: 10.3238/zfa.2012.0069-0076
Cerebrospinal fluid fatty acids in glucocerebrosidase-associated Parkinson's disease.
Schmid SP, Schleicher ED, Cegan A, Deuschle C, Baur S, Hauser AK, Synofzik M, Srulijes K, Brockmann K, Berg D, Maetzler W. Mov Disord. 2012 Feb;27(2):288-93. doi: 10.1002/mds.23984. Epub 2011 Oct 21.
Phosphorylated α-Synuclein in Parkinson's Disease.
Wang Y, Shi M, Chung KA, Zabetian CP, Leverenz JB, Berg D, Srulijes K, Trojanowski JQ, Lee VM, Siderowf AD, Hurtig H, Litvan I, Schiess MC, Peskind ER, Masuda M, Hasegawa M, Lin X, Pan C, Galasko D, Goldstein DS, Jensen PH, Yang H, Cain KC, Zhang J. Sci Transl Med. 2012 Feb 15;4(121):121ra20.
Viral and inflammatory triggers of neurodegenerative diseases.
Deleidi M, Isacson O. Sci Transl Med. 2012 Feb 15;4(121):121ps3.
Beyond the comparator model.
Synofzik M, Vosgerau G. Conscious Cogn. 2012 Mar;21(1):1-3. Epub 2012 Feb 1.
Socio-economic risk factors for incident restless legs syndrome in the general population.
Szentkiralyi A, Fendrich K, Hoffmann W, Happe S, Berger K. J Sleep Res. 2012 Feb 27. doi: 10.1111/j.1365-2869.2012.01001.x. [Epub ahead of print]
Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders.
Ersland KM, Christoforou A, Stansberg C, Espeseth T, Mattheisen M, Mattingsdal M, Hardarson GA, Hansen T, Fernandes CP, Giddaluru S, Breuer R, Strohmaier J, Djurovic S, Nöthen MM, Rietschel M, Lundervold AJ, Werge T, Cichon S, Andreassen OA, Reinvang I, Steen VM, Le Hellard S. PLoS One. 2012;7(2):e31687. Epub 2012 Feb 22.
Amygdala Lesion Profoundly Alters Altruistic Punishment.
Scheele D, Mihov Y, Kendrick KM, Feinstein JS, Reich H, Maier W, Hurlemann R. Biol Psychiatry. 2012 Feb 24. [Epub ahead of print]
Neuron-specific Deletion of a Single Copy of the Insulin-like Growth Factor-1 Receptor Gene Reduces Fat Accumulation during Aging.
Freude S, Schilbach K, Hettich MM, Brönneke HS, Zemva J, Krone W, Schubert M. Horm Metab Res. 2012 Feb;44(2):99-104. Epub 2011 Dec 23.
Family History and APOE-4 Genetic Risk in Alzheimer's Disease.
Donix M, Small GW, Bookheimer SY. Neuropsychol Rev. 2012 Feb 23. [Epub ahead of print]
Intrathecal application of autologous bone marrow cell preparations in parkinsonian syndromes.
Storch A, Csoti I, Eggert K, Henriksen T, Plate A, Lorrain M, Oertel WH, Antonini A. Mov Disord. 2012 Feb 23. doi: 10.1002/mds.24920. [Epub ahead of print]
White matter pathology in ALS and lower motor neuron ALS variants: a diffusion tensor imaging study using tract-based spatial statistics.
Prudlo J, Bißbort C, Glass A, Grossmann A, Hauenstein K, Benecke R, Teipel SJ. J Neurol. 2012 Feb 21. [Epub ahead of print]
Neurocognitive impairments in non-deprived smokers-results from a population-based multi-center study on smoking-related behavior.
Wagner M, Schulze-Rauschenbach S, Petrovsky N, Brinkmeyer J, von der Goltz C, Gründer G, Spreckelmeyer KN, Wienker T, Diaz-Lacava A, Mobascher A, Dahmen N, Clepce M, Thuerauf N, Kiefer F, de Millas JW, Gallinat J, Winterer G. Addict Biol. 2012 Feb 17. doi: 10.1111/j.1369-1600.2011.00429.x. [Epub ahead of print]
Structural basis of β-amyloid-dependent synaptic dysfunctions.
Haupt C, Leppert J, Rönicke R, Meinhardt J, Yadav JK, Ramachandran R, Ohlenschläger O, Reymann KG, Görlach M, Fändrich M. Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1576-9. doi: 10.1002/anie.201105638. Epub 2012 Jan 10.
Genome-wide association study of vascular dementia.
Schrijvers EM, Schürmann B, Koudstaal PJ, van den Bussche H, Van Duijn CM, Hentschel F, Heun R, Hofman A, Jessen F, Kölsch H, Kornhuber J, Peters O, Rivadeneira F, Rüther E, Uitterlinden AG, Riedel-Heller S, Dichgans M, Wiltfang J, Maier W, Breteler MM, Ikram MA. Stroke. 2012 Feb;43(2):315-9. Epub 2011 Nov 23.
Automated brain structure segmentation based on atlas registration and appearance models.
van der Lijn F, de Bruijne M, Klein S, den Heijer T, Hoogendam YY, van der Lugt A, Breteler MM, Niessen WJ. IEEE Trans Med Imaging. 2012 Feb;31(2):276-86. Epub 2011 Sep 19.
Automated measurement of local white matter lesion volume.
van der Lijn F, Verhaaren BF, Ikram MA, Klein S, de Bruijne M, Vrooman HA, Vernooij MW, Hammers A, Rueckert D, van der Lugt A, Breteler MM, Niessen WJ. Neuroimage. 2012 Feb 15;59(4):3901-8. Epub 2011 Nov 11.
Peripheral and central inputs shape network dynamics in the developing visual cortex in vivo.
Siegel F, Heimel JA, Peters J, Lohmann C. Curr Biol. 2012 Feb 7;22(3):253-8. Epub 2012 Jan 19.
Pusher syndrome: its cortical correlate.
Baier B, Janzen J, Müller-Forell W, Fechir M, Müller N, Dieterich M. J Neurol. 2012 Feb;259(2):277-83. Epub 2011 Aug 10.
The α-Helical Content of the Transmembrane Domain of the British Dementia Protein-2 (Bri2) Determines Its Processing by Signal Peptide Peptidase-like 2b (SPPL2b).
Fluhrer R, Martin L, Klier B, Haug-Kröper M, Grammer G, Nuscher B, Haass C. J Biol Chem. 2012 Feb 10;287(7):5156-63. Epub 2011 Dec 22.
BACE1 Dependent Neuregulin Processing: Review.
Fleck D, Garratt AN, Haass C, Willem M. Curr Alzheimer Res. 2012 Feb 1;9(2):178-83.
Lack of Pur-alpha alters postnatal brain development and causes megalencephaly.
Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Müller I, Schüller U, Kretzschmar H, Wolf E, Herms J. Hum Mol Genet. 2012 Feb 1;21(3):473-84. Epub 2011 Oct 18.
Assembly of a new growth cone after axotomy: the precursor to axon regeneration.
Bradke F, Fawcett JW, Spira ME. Nat Rev Neurosci. 2012 Feb 15;13(3):183-93. doi: 10.1038/nrn3176.
Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures.
HG Jahnke, A Braesigk, TG Mack, S Pönick, F Striggow, AA Robitzki; Biosens Bioelectron. 2012 Feb 15;32(1):250-8. Epub 2011 Dec 23.
Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.
V Velanac, T Unterbarnscheidt, W Hinrichs, MN Gummert, TM Fischer, MJ Rossner, A Trimarco, V Brivio, C Taveggia, M Willem, C Haass, W Möbius, KA Nave, MH Schwab; Glia. 2012 Feb;60(2):203-17. doi: 10.1002/glia.21255. Epub 2011 Nov 2.
Glial cells in adult neurogenesis.
J Morrens, W Van Den Broeck, G Kempermann; Glia. 2012 Feb;60(2):159-74. doi: 10.1002/glia.21247. Epub 2011 Nov 10.
Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics.
Gerlach M, Maetzler W, Broich K, Hampel H, Rems L, Reum T, Riederer P, Stöffler A, Streffer J, Berg D. J Neural Transm. 2012 Jan;119(1):39-52. Epub 2011 Jul 14.
Co-occurrence of parkinsonism and dementia in clinical practice: relevant differential diagnoses.
Liepelt-Scarfone I, Jamour M, Maetzler W. Z Gerontol Geriatr. 2012 Jan;45(1):23-33.
Salivary prions in sheep and deer.
G Tamgüney, JR Richt, AN Hamir, JJ Greenlee, MW Miller, LL Wolfe, TM Sirochman, AJ Young, DV Glidden, NL Johnson, K Giles, SJ DeArmond, SB Prusiner SB (2011), Prion, in press. DOI: 10.4161/pri.6.1.16984
Head injury, alpha-synuclein Rep1, and Parkinson's disease.
Goldman SM, Kamel F, Ross GW, Jewell SA, Bhudhikanok GS, Umbach D, Marras C, Hauser RA, Jankovic J, Factor SA, Bressman S, Lyons KE, Meng C, Korell M, Roucoux DF, Hoppin JA, Sandler DP, Langston JW, Tanner CM. Ann Neurol. 2012 Jan;71(1):40-8. doi: 10.1002/ana.22499.
Fluorodeoxyglucose positron emission tomography in Richardson’s syndrome and progressive supranuclear palsy-parkinsonism.
Srulijes K, Reimold M, Liscic RM, Bauer S, Dietzel E, Liepelt-Scarfone I, Berg D, Maetzler W. Mov Disord. 2012 Jan;27(1):151-5.
Creutzfeldt-Jakob disease and mad cows: lessons learnt from yeast cells.
Hofmann J, Wolf H, Grassmann A, Arndt V, Graham J, Vorberg I. Swiss Med Wkly. 2012 Jan 24;142:0. doi: 10.4414/smw.2012.13505.
Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.
Fava E, Dehghany J, Ouwendijk J, Müller A, Niederlein A, Verkade P, Meyer-Hermann M, Solimena M. Diabetologia. 2012 Jan 18. [Epub ahead of print]
Cerebrospinal fluid soluble amyloid-β protein precursor as a potential novel biomarkers of Alzheimer's disease.
Lewczuk P, Popp J, Lelental N, Kölsch H, Maier W, Kornhuber J, Jessen F. J Alzheimers Dis. 2012 Jan;28(1):119-25.
Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1.
Kaut O, Schmitt I, Wüllner U. Neurogenetics. 2012 Jan 12. [Epub ahead of print]
Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice.
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Fear Processing and Social Networking in the Absence of a Functional Amygdala.
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