Research at the DZNE

Researchers at DZNE are engaged in understanding commonalities and differences between various brain diseases with the aim of developing new preventive and therapeutic approaches. At DZNE, fundamental research is tightly interconnected with clinical, epidemiological and health sciences with the aim of finding new diagnostic markers and enabling rapid development of new cures.

Translation at DZNE

To foster translation, DZNE tightly links fundamental research to clinical and population studies and to health care research.

Fundamental Research. The molecular and cellular bases of neurodegenerative diseases are still poorly understood. In order to develop better therapies, scientists at DZNE investigate how nerve cells are damaged and which targets are most relevant for the development of new medicines.

Clinical Research. Translation of new research concepts into patient benefits has been problematic. Key aims at DZNE are to improve early diagnosis and to facilitate translation and delivery of new treatments to patients affected by neurodegeneration.

Population Studies. DZNE scientists study representative cross-sections of the population over decades to reveal risk factors for neurodegenerative diseases, including lifestyle and genetic predisposition. These studies are essential for defining early diagnostic markers.

Health Care Research. Better care for patients is essential to reduce the impact of neurodegenerative diseases in the short and medium term. The primary goal of current DZNE studies is to improve the quality of life of patients affected by cognitive impairment and to better support their relatives and caregivers.