Publications
A general framework for robust and efficient association analysis in family-based designs: quantitative and dichotomous phenotypes.
Won S, Lange C. Stat Med. 2013 Jun 6. doi: 10.1002/sim.5865. [Epub ahead of print]
Scalability and internal consistency of the German version of the dementia-specific quality of life instrument QUALIDEM in nursing homes -- a secondary data analysis.
Dichter MN, Dortmann O, Halek M, Meyer G, Holle D, Nordheim J, Bartholomeyczik S. Health Qual Life Outcomes. 2013 Jun 5;11(1):91. [Epub ahead of print]
Validation of the German version of the extended ALS functional rating scale as a patient-reported outcome measure.
Abdulla S, Vielhaber S, Körner S, Machts J, Heinze HJ, Dengler R, Petri S. J Neurol. 2013 Jun 5. [Epub ahead of print]
Drain of the brain: low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system.
Ovsepian SV, Herms J. Neurobiol Aging. 2013 Jun 5. pii: S0197-4580(13)00203-0. doi: 10.1016/j.neurobiolaging.2013.05.005. [Epub ahead of print]
Viral Delivery of Antioxidant Genes as a Therapeutic Strategy in Experimental Models of Amyotrophic Lateral Sclerosis.
Nanou A, Higginbottom A, Valori CF, Wyles M, Ning K, Shaw P, Azzouz M. Mol Ther. 2013 Jun 4. doi: 10.1038/mt.2013.115. [Epub ahead of print]
The CERAD Neuropsychological Assessment Battery Total Score Detects and Predicts Alzheimer Disease Dementia with High Diagnostic Accuracy.
Wolfsgruber S, Jessen F, Wiese B, Stein J, Bickel H, Mösch E, Weyerer S, Werle J, Pentzek M, Fuchs A, Köhler M, Bachmann C, Riedel-Heller SG, Scherer M, Maier W, Wagner M; AgeCoDe study group. Am J Geriatr Psychiatry. 2013 Jun 4. pii: S1064-7481(13)00115-2. doi: 10.1016/j.jagp.2012.08.021. [Epub ahead of print]
Progressive cognitive dysfunction in spinocerebellar ataxia type 3.
Roeske S, Filla I, Heim S, Amunts K, Helmstaedter C, Wüllner U, Wagner M, Klockgether T, Minnerop M. Mov Disord. 2013 Jun 4. doi: 10.1002/mds.25512. [Epub ahead of print]
Alteration of Ganglioside Biosynthesis Responsible for Complex Hereditary Spastic Paraplegia.
Boukhris A, Schule R, Loureiro JL, Lourenço CM, Mundwiller E, Gonzalez MA, Charles P, Gauthier J, Rekik I, Acosta Lebrigio RF, Gaussen M, Speziani F, Ferbert A, Feki I, Caballero-Oteyza A, Dionne-Laporte A, Amri M, Noreau A, Forlani S, Cruz VT, Mochel F, Coutinho P, Dion P, Mhiri C, Schols L, Pouget J, Darios F, Rouleau GA, Marques W Jr, Brice A, Durr A, Zuchner S, Stevanin G. Am J Hum Genet. 2013 Jun 4. pii: S0002-9297(13)00219-X. doi: 10.1016/j.ajhg.2013.05.006. [Epub ahead of print]
The effects of dementia care mapping on nursing home residents' quality of life and staff attitudes: design of the quasi-experimental study Leben-QD II.
Halek M, Dichter MN, Quasdorf T, Riesner C, Bartholomeyczik S. BMC Geriatr. 2013 Jun 1;13(1):53. [Epub ahead of print]
Cognitive aging-chance and challenge.
Teipel S. Geriatric Mental Health Care. Volume 1, Issue 2, June 2013, Pages 27-28. DOI: 10.1016/j.gmhc.2013.04.008
Activation and regulation of the inflammasomes.
Latz E, Xiao TS, Stutz A. Nat Rev Immunol. 2013 Jun;13(6):397-411. doi: 10.1038/nri3452.
Future outpatient health-care utilisation in an ageing population: Projections up to the year 2020 based on the Study of Health in Pomerania (SHIP).
Siewert U, Fendrich K, Markus MRP, Baumeister SE, Doblhammer-Reiter G, Scholz RD, Hoffmann W. Journal of Public Health (Germany). Volume 21, Issue 3, June 2013, Pages 289-296. DOI: 10.1007/s10389-012-0550-7
The demography and epidemiology of dementia.
Doblhammer G, Fink A, Fritze T, Günster C. Geriatric Mental Health Care. Volume 1, Issue 2, June 2013, Pages 29-33. DOI: 10.1016/j.gmhc.2013.04.002
Cognitive assistance to support social integration in Alzheimer's disease.
Koldrack P, Luplow M, Kirste T, Teipel S. Geriatric Mental Health Care. Volume 1, Issue 2, June 2013, Pages 39-45. DOI: 10.1016/j.gmhc.2013.04.005.
Robust Automated Detection of Microstructural White Matter Degeneration in Alzheimer's Disease Using Machine Learning Classification of Multicenter DTI Data.
Dyrba M, Ewers M, Wegrzyn M, Kilimann I, Plant C, Oswald A, Meindl T, Pievani M, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Kirste T, Teipel SJ; EDSD study group. PLoS One. 2013 May 31;8(5):e64925. doi: 10.1371/journal.pone.0064925. Print 2013.
Induced neural stem cells (iNSCs) in neurodegenerative diseases.
Hermann A, Storch A. J Neural Transm. 2013 May 30. [Epub ahead of print]
Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons.
Ovsepian SV, Antyborzec I, O'Leary VB, Zaborszky L, Herms J, Oliver Dolly J. Brain Struct Funct. 2013 May 29. [Epub ahead of print]
The potential of stem cell research for the treatment of neuronal damage in glaucoma.
Karl MO. Cell Tissue Res. 2013 May 25. [Epub ahead of print]
COMT x DRD4 Epistasis Impacts Prefrontal Cortex Function Underlying Response Control.
Heinzel S, Dresler T, Baehne CG, Heine M, Boreatti-Hümmer A, Jacob CP, Renner TJ, Reif A, Lesch KP, Fallgatter AJ, Ehlis AC. Cereb Cortex. 2013 Jun;23(6):1453-62. doi: 10.1093/cercor/bhs132. Epub 2012 May 22.
The ε4 genotype of apolipoprotein E and white matter integrity in Alzheimer's disease.
Kljajevic V, Meyer P, Holzmann C, Dyrba M, Kasper E, Bokde AL, Fellgiebel A, Meindl T, Hampel H, Teipel S; EDSD study group. Alzheimers Dement. 2013 May 21. pii: S1552-5260(13)00084-8. doi: 10.1016/j.jalz.2013.02.008. [Epub ahead of print]
Biological and clinical characteristics of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 in the longitudinal RISCA study: analysis of baseline data.
Jacobi H, Reetz K, du Montcel ST, Bauer P, Mariotti C, Nanetti L, Rakowicz M, Sulek A, Durr A, Charles P, Filla A, Antenora A, Schöls L, Schicks J, Infante J, Kang JS, Timmann D, Fabio RD, Masciullo M, Baliko L, Bela M, Boesch S, Bürk K, Peltz A, Schulz JB, Dufaure-Garé I, Klockgether T. Lancet Neurol. 2013 May 21. pii: S1474-4422(13)70104-2. doi: 10.1016/S1474-4422(13)70104-2. [Epub ahead of print]
N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits.
Bouter Y, Dietrich K, Wittnam JL, Rezaei-Ghaleh N, Pillot T, Papot-Couturier S, Lefebvre T, Sprenger F, Wirths O, Zweckstetter M, Bayer TA. Acta Neuropathol. 2013 May 18. [Epub ahead of print]
The DLK signalling pathway-a double-edged sword in neural development and regeneration.
Tedeschi A, Bradke F. EMBO Rep. 2013 May 17. doi: 10.1038/embor.2013.64. [Epub ahead of print]
Between new genetic discoveries and large randomized trials-neurological research in the era of systems medicine.
Misgeld T, Lichtenthaler SF, Dichgans M. EMBO Rep. 2013 Jun 3;14(6):489-92. doi: 10.1038/embor.2013.70. Epub 2013 May 14.
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