Publications

Immunochip-based analysis: High-density genotyping of immune-related loci sheds further light on the autoimmune genetic architecture of alopecia areata

Redler S, Angisch M, Heilmann S, Wolf S, Barth S, Basmanav BF, Giehl KA, Hanneken S, Eigelshoven S, Mangold E, Kruse R, Blaumeiser B, Böhm M, Knapp M, Garcia Bartels N, Lutz G, Wolff H, Blume-Peytavi U, Nöthen MM, Becker T, Betz RC.

J Invest Dermatol. 2015 Mar;135(3):919-21. doi: 10.1038/jid.2014.459. Epub 2014 Oct 22. No abstract available.

 


Gamma Power Reductions Accompany Stimulus-Specific Representations of Dynamic Events

Zhang H, Fell J, Staresina BP, Weber B, Elger CE, Axmacher N.

Curr Biol. 2015 Feb 12. pii: S0960-9822(15)00013-5. doi: 10.1016/j.cub.2015.01.011. [Epub ahead of print]

 


open Pubmed Abstract

Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments

Ovespian SV, Bodeker M, O'Leary VB, Lawrence GW, Oliver Dolly J.

Brain Struct Funct. 2015 Feb 11. [Epub ahead of print]

 


open Pubmed Abstract

Requirements for mutant and wild-type prion protein misfolding in vitro

Noble GP, Walsh DJ, Miller MB, Jackson WS, Supattapone S.

Biochemistry. 2015 Feb 10;54(5):1180-7. doi: 10.1021/bi501495j. Epub 2015 Jan 22.

 


open Pubmed Abstract

Multimodal analysis of functional and structural disconnection in Alzheimer's disease using multiple kernel SVM

Dyrba M, Grothe M, Kirste T, Teipel SJ.

Hum Brain Mapp. 2015 Feb 9. doi: 10.1002/hbm.22759. [Epub ahead of print]

 


open Pubmed Abstract

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type

Popp J, Wolfsgruber S, Heuser I, Peters O, Hüll M, Schröder J, Möller HJ, Lewczuk P, Schneider A, Jahn H, Luckhaus C, Perneczky R, Frölich L, Wagner M, Maier W, Wiltfang J, Kornhuber J, Jessen F.

Neurobiol Aging. 2015 Feb;36(2):601-7. doi: 10.1016/j.neurobiolaging.2014.10.031. Epub 2014 Oct 31.

 


open Pubmed Abstract

Selective processing of buildings and faces during working memory: The role of the ventral striatum

Haeger A, Lee H, Fell J, Axmacher N.

Eur J Neurosci. 2015 Feb;41(4):505-13. doi: 10.1111/ejn.12808. Epub 2014 Dec 22.

 


open Pubmed Abstract

Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model.

Schmöle AC, Lundt R, Ternes S, Albayram Ö, Ulas T, Schultze JL, Bano D, Nicotera P, Alferink J, Zimmer A.

Neurobiol Aging. 2015 Feb;36(2):710-9. doi: 10.1016/j.neurobiolaging.2014.09.019. Epub 2014 Sep 28.

 


open Pubmed Abstract

Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity

Keeney JG, O'Bleness MS, Anderson N, Davis JM, Arevalo N, Busquet N, Chick W, Rozman J, Hölter SM, Garrett L, Horsch M; German Mouse Clinic Consortium, Beckers J, Wurst W, Klingenspor M, Restrepo D, de Angelis MH, Sikela JM.

Mamm Genome. 2015 Feb;26(1-2):33-42. doi: 10.1007/s00335-014-9545-8. Epub 2014 Oct 12.

 


open Pubmed Abstract

Reasons for mild parkinsonian signs - Which constellation may indicate neurodegeneration?

Lerche S, Brockmann K, Wurster I, Gaenslen A, Roeben B, Holz D, Eschweiler GW, Maetzler W, Berg D.

Parkinsonism Relat Disord. 2015 Feb;21(2):126-30. doi: 10.1016/j.parkreldis.2014.11.018. Epub 2014 Nov 28.

 


open Pubmed Abstract

Vestibular compensation in cerebellar stroke patients

Baier B, Müller N, Rhode F, Dieterich M.

Eur J Neurol. 2015 Feb;22(2):416-8. doi: 10.1111/ene.12475. Epub 2014 Jun 19.

 


open Pubmed Abstract

Predictors of hippocampal atrophy in critically ill patients

Lindlau A, Widmann CN, Putensen C, Jessen F, Semmler A, Heneka MT.

Eur J Neurol. 2015 Feb;22(2):410-5. doi: 10.1111/ene.12443. Epub 2014 Apr 12.

 


open Pubmed Abstract

Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors

Sarvestani ST, Stunden HJ, Behlke MA, Forster SC, McCoy CE, Tate MD, Ferrand J, Lennox KA, Latz E, Williams BR, Gantier MP.

Nucleic Acids Res. 2015 Jan 30;43(2):1177-88. doi: 10.1093/nar/gku1343. Epub 2014 Dec 24.

 


open Pubmed Abstract

Predicting Prodromal Alzheimer's Disease in Subjects with Mild Cognitive Impairment Using Machine Learning Classification of Multimodal Multicenter Diffusion-Tensor and Magnetic Resonance Imaging Data

Dyrba M, Barkhof F, Fellgiebel A, Filippi M, Hausner L, Hauenstein K, Kirste T, Teipel SJ; the EDSD study group.

J Neuroimaging. 2015 Jan 28. doi: 10.1111/jon.12214. [Epub ahead of print]

 


open Pubmed Abstract

Bax regulates neuronal Ca2+Homeostasis

D'Orsi B, Kilbride SM, Chen G, Perez Alvarez S, Bonner HP, Pfeiffer S, Plesnila N, Engel T, Henshall DC, Düssmann H, Prehn JH.

J Neurosci. 2015 Jan 28;35(4):1706-22. doi: 10.1523/JNEUROSCI.2453-14.2015.

 


open Pubmed Abstract

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells

Bartesaghi S, Graziano V, Galavotti S, Henriquez NV, Betts J, Saxena J, A D, Karlsson A, Martins LM, Capasso M, Nicotera P, Brandner S, De Laurenzi V, Salomoni P.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1059-64. doi: 10.1073/pnas.1413165112. Epub 2015 Jan 12.

 


open Pubmed Abstract

The inflammasomes and autoinflammatory syndromes

Broderick L, De Nardo D, Franklin BS, Hoffman HM, Latz E.

Annu Rev Pathol. 2015 Jan 24;10:395-424. doi: 10.1146/annurev-pathol-012414-040431. Epub 2014 Nov 19.

 


open Pubmed Abstract

Clinical and Neuropathological Features of Spastic Ataxia in a Spanish Family with Novel Compound Heterozygous Mutations in STUB1

Bruno D, Grothe MJ, Nierenberg J, Zetterberg H, Blennow K, Teipel SJ, Pomara N.

Neuropsychologia. 2015 Jan 19;69C:1-8. doi: 10.1016/j.neuropsychologia.2015.01.025. [Epub ahead of print]

 


open Pubmed Abstract

A study on the specificity of the association between hippocampal volume and delayed primacy performance in cognitively intact elderly individuals

Bruno D, Grothe MJ, Nierenberg J, Zetterberg H, Blennow K, Teipel SJ, Pomara N.

Neuropsychologia. 2015 Jan 19;69C:1-8. doi: 10.1016/j.neuropsychologia.2015.01.025. [Epub ahead of print]

 


open Pubmed Abstract

Danger signaling in atherosclerosis

Zimmer S, Grebe A, Latz E.

Circ Res. 2015 Jan 16;116(2):323-340. Review.

 


open Pubmed Abstract

The immunoregulator soluble TACI Is released by ADAM10 and reflects B cell activation in autoimmunity

Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E.

J Immunol. 2015 Jan 15;194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10.

 


open Pubmed Abstract

Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8

Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T.

J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10.

 


open Pubmed Abstract

Cholinergic basal forebrain structure influences the reconfiguration of white matter connections to support residual memory in mild cognitive impairment

Ray NJ, Metzler-Baddeley C, Khondoker MR, Grothe MJ, Teipel S, Wright P, Heinsen H, Jones DK, Aggleton JP, O'Sullivan MJ.

J Neurosci. 2015 Jan 14;35(2):739-47. doi: 10.1523/JNEUROSCI.3617-14.2015.

 


open Pubmed Abstract

Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease

Depboylu C, Rösler TW, de Andrade A, Oertel WH, Höglinger GU.

J Neurochem. 2015 Jan 10. doi: 10.1111/jnc.13026. [Epub ahead of print]

 


open Pubmed Abstract

Postsynaptic and spiking activity of pyramidal cells, the principal neurons in the rat hippocampal CA1 region, does not control the resultant BOLD response: a combined electrophysiologic and fMRI approach

Scherf T, Angenstein F.

J Cereb Blood Flow Metab. 2015 Jan 7. doi: 10.1038/jcbfm.2014.252. [Epub ahead of print]

 


open Pubmed Abstract

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