Publications
Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success.
Balbach ST, Esteves TC, Houghton FD, Siatkowski M, Pfeiffer MJ, Tsurumi C, Kanzler B, Fuellen G, Boiani M. PLoS One. 2012;7(4):e35322. Epub 2012 Apr 18.
Atrophy of the cholinergic basal forebrain over the adult age range and in early stages of Alzheimer's disease
M Grothe, H Heinsen, SJ Teipel; Biol Psychiatry. 2012 May 1;71(9):805-13. Epub 2011 Aug 4.
Cognitive impairment in primary ambulatory health care: pharmacotherapy and the use of potentially inappropriate medicine.
Fiss T, Thyrian JR, Fendrich K, van den Berg N, Hoffmann W. Int J Geriatr Psychiatry. 2012 Apr 16. doi: 10.1002/gps.3806. [Epub ahead of print]
Identification of common variants associated with human hippocampal and intracranial volumes.
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann O, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; the Alzheimer's Disease Neuroimaging Initiative (ADNI); EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group (SYS), Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, Decarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM. Nat Genet. 2012 Apr 15;44(5):552-561. doi: 10.1038/ng.2250.
Medication review for dementia patients.[Medikationsreview in der psychiatrischen institutsambulanz.]
Jahns KP, Kilimann I, Ritter CA, Hoffmann W, Teipel SJ, Fiss T. Med Monatsschr Pharm. 2012 Mar;35(3):95-103.
Socio-economic risk factors for incident restless legs syndrome in the general population.
Szentkiralyi A, Fendrich K, Hoffmann W, Happe S, Berger K. J Sleep Res. 2012 Feb 27. doi: 10.1111/j.1365-2869.2012.01001.x. [Epub ahead of print]
White matter pathology in ALS and lower motor neuron ALS variants: a diffusion tensor imaging study using tract-based spatial statistics.
Prudlo J, Bißbort C, Glass A, Grossmann A, Hauenstein K, Benecke R, Teipel SJ. J Neurol. 2012 Feb 21. [Epub ahead of print]
The future of Alzheimer's disease: the next 10 years.
H Hampel, D Prvulovic, S Teipel, F Jessen, C Luckhaus, L Frölich, MW Riepe, R Dodel, T Leyhe, L Bertram, W Hoffmann, F Faltraco; German Task Force on Alzheimer's Disease (GTF-AD); Prog Neurobiol. 2011 Dec;95(4):718-28. Epub 2011 Nov 22.
Multicenter stability of diffusion tensor imaging measures: A European clinical and physical phantom study.
SJ Teipel, S Reuter, B Stieltjes, J Acosta-Cabronero, U Ernemann, A Fellgiebel, M Filippi, G Frisoni, F Hentschel, F Jessen, S Klöppel, T Meindl, PJ Pouwels, KH Hauenstein, H Hampel; Psychiatry Res. 2011 Dec 30;194(3):363-71. Epub 2011 Nov 9.
Intra- and inter-cortical motor excitability in Alzheimer's disease.
J Hoeppner, M Wegrzyn, J Thome, A Bauer, I Oltmann, J Buchmann, S Teipel; J Neural Transm. 2011 Nov 13. [Epub ahead of print]
Incidence of restless legs syndrome in two population-based cohort studies in Germany.
A Szentkiralyi, K Fendrich, W Hoffmann, S Happe, K Berger; Sleep Med. 2011 Oct;12(9):815-20.
Frequency and determinants of potential drug-drug interactions in an elderly population receiving regular home visits by GPs - results of the home medication review in the AGnES-studies
W Hoffmann, N Van Den Berg, JR Thyrian, T Fiss; Pharmacoepidemiol Drug Saf. 2011 Sep 15. doi: 10.1002/pds.2224. [Epub ahead of print]
Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: Effect of different processing and analysis approaches on sample sizes.
SJ Teipel, O Peters, I Heuser, F Jessen, W Maier, L Froelich, S Arlt, MHüll, HJ Gertz, J Kornhuber, J Wiltfang, J Thome, O Rienhoff, T Meindl, H Hampel, M Grothe; World J Biol Psychiatry. 2011 Sep;12 Suppl 1:109-13.
Quality features of German memory clinics - A cross-sectional study
S Lueke, N Kehrwieder, W Hoffmann, S Teipel, S Fleßa; Nervenarzt. 2011 Sep 2. [Epub ahead of print]
Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice
M Krohn, C Lange, J Hofrichter, K Scheffler, J Stenzel, J Steffen, T Schumacher, T Brüning, A-S Plath, F Alfen, A Schmidt, F Winter, K Rateitschak, A Wree, J Gsponer, LC Walker, J Pahnke; J Clin Invest. 2011 Oct 3;121(10):3924-31. doi: 10.1172/JCI57867. Epub 2011 Sep 1.
Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: Effect of different processing and analysis approaches on sample sizes.
SJ Teipel, O Peters, I Heuser, F Jessen, W Maier, L Froelich, S Arlt, MHüll, HJ Gertz, J Kornhuber, J Wiltfang, J Thome, O Rienhoff, T Meindl, H Hampel, M Grothe; World J Biol Psychiatry. 2011 Sep;12 Suppl 1:109-13.
Live longer, suffer more? Trends in life expectancy and health
G Doblhammer, D Kreft; Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Aug;54(8):907-14.
Longitudinal changes of fractial anisotropy in Alzheimer’s disease patients treated with galantamine: a 12-month randomized, placebo-controlled, double-blinded study.
Y Likitjaroen, T Meindl, U Friese,M Wagner, K Buerger, H Hampel, SJ Teipel, Eur Arch Psychiatry Clin Neurosci, 2011 Aug 5, Epub ahead of print.
A genome-wide association study of aging
S Walter, G Atzmon, EW Demerath, ME Garcia, RC Kaplan, M Kumari, KL Lunetta, Y Milaneschi, T Tanaka, GJ Tranah, U Völker, L Yu, A Arnold, EJ Benjamin, R Biffar, AS Buchman, E Boerwinkle, D Couper, PL De Jager, DA Evans, TB Harris, W Hoffmann, A Hofman, D Karasik, DP Kiel, T Kocher, M Kuningas, LJ Launer, KK Lohman, PL Lutsey, J Mackenbach, K Marciante, BM Psaty, EM Reiman, JI Rotter, S Seshadri, MD Shardell, AV Smith, C van Duijn, J Walston, MC Zillikens, S Bandinelli, SE Baumeister, DA Bennett, L Ferrucci, V Gudnason, M Kivimaki, Y Liu, JM Murabito, AB Newman, H Tiemeier, N Franceschini; Neurobiol Aging. 2011 Nov;32(11):2109.e15-28. Epub 2011 Jul 22.
Antihypertensive therapy is associated with reduced rate of conversion to Alzheimer's disease in midregional proatrial natriuretic Peptide stratified subjects with mild cognitive impairment.
P Schneider, K Buerger, S Teipel, O Uspenskaya, O Hartmann, O Hansson, L Minthon, D Rujescu, HJ Moeller, H Zetterberg, K Blennow, A Ernst, A Bergmann, H Hampel; Biol Psychiatry. 2011 Jul 15;70(2):145-51. Epub 2011 Mar 31.
Structural and functional neuronal connectivity in Alzheimer's disease : A combined DTI and fMRI study.
J Soldner, T Meindl, W Koch, AL Bokde, MF Reiser, HJ Möller, K Bürger, H Hampel, SJ Teipel; Nervenarzt. 2011 Jun 30. [Epub ahead of print]
Staging Alzheimer’s disease progression with multimodality neuroimaging.
M Ewers, GB Frisoni, SJ Teipel, LT Grinberg, E Jr. Amaro, H Heinsen, PM Thompson, H Hampel, Prog. Neurobiol, 2011 June 22, Epub ahead of print.
Isolated motor neglect following infarction of the posterior limb of the right internal capsule: a case study with diffusion tensor imaging-based tractography.
Y Likitjaroen, NC Suwanwela, AJ Mitchell, S Lerdlum, K Phanthumchinda, SJ Teipel; J Neurol. 2012 Jan;259(1):100-5. Epub 2011 Jun 22.
Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
M Ewers, S Schmitz, O Hansson, C Walsh, A Fitzpatrick, D Bennett, L Minthon, JQ Trojanowski, LM Shaw, YO Faluyi, B Vellas, B Dubois, K Blennow, K Buerger, SJ Teipel, M Weiner, H Hampel, Alzheimer's Disease Neuroimaging Initiative; Neurobiol Aging. 2011 Jun 16. [Epub ahead of print]
Long-Term Stability of Alzheimer's Disease Biomarker Proteins in Cerebrospinal Fluid.
CG Schipke, F Jessen, S Teipel, C Luckhaus, J Wiltfang, H Esselmann, L Frölich, W Maier, E Rüther, FL Heppner, S Prokop, I Heuser, O Peters; J Alzheimers Dis. 2011 May 23. [Epub ahead of print]
Left Anterior Temporal Lobe Sustains Naming in Alzheimer's Dementia and Mild Cognitive Impairment.
L Frings, S Klöppel, S Teipel, O Peters, L Frölich, J Pantel, J Schröder, HJ Gertz, S Arlt, I Heuser, J Kornhuber, J Wiltfang, W Maier, F Jessen, H Hampel, M Hüll; Curr Alzheimer Res. 2011 May 18. [Epub ahead of print]
Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression.
SJ Teipel, R Buchert, J Thome, H Hampel, J Pahnke; Prog Neurobiol. 2011 May 12. [Epub ahead of print]
Zeitbedarf und Kosten für die Umsetzung eines Medikamentenreviews und assoziierter pharmazeutischer und medizinischer Evaluation im ambulanten Versorgungssektor.
T Fiß, M Schaefer, N van den Berg, W Hoffmann; Gesundheitswesen. 2011 May 11. [Epub ahead of print]
Towards a neuroimaging biomarker in amyotrophic lateral sclerosis.
M. R Turner, J. Grosskreutz, J. Kassubek, S. Abrahams, F. Agosta, M. Benatar, M. Filippi, L. H. Goldstein, M. van den Heuvel, S. Kalra, D. Lulé, B. Mohammadi & other members of ‘The 1st NISALS’*
*Other contributors to The 1st Neuroimaging Symposium in ALS (NISALS): N. Atassi, P. Bede, H. Benali, Chr. Enzinger, Chr. Gaser, L. Jelsone-Swain, H.-P. Müller, R. W. Orrell, P.-F. Pradat, J. Prudlo, S. Ropele, R.Sharma, V. Silani, A. Simmons, S. Smith, S. Teipel, A. Toosy, S. Tsermentseli, P. Van Damme, E. Verstraete, R. Welsh, M. Wittstock; The Lancet Neurology, Volume 10, Issue 5, Pages 400 - 403, May 2011
Proteomic analysis of mouse oocytes reveals 28 candidate factors of the "reprogrammome".
MJ Pfeiffer, M Siatkowski, Y Paudel, ST Balbach, N Baeumer, N Crosetto, HC Drexler, G Fuellen, M Boiani; J Proteome Res. 2011 May 6;10(5):2140-53. Epub 2011 Mar 29.
Effects of a 6-Month Cognitive Intervention Program on Brain Metabolism in Amnestic Mild Cognitive Impairment and Mild Alzheimer's Disease.
S Förster, VC Buschert, HG Buchholz, SJ Teipel, U Friese, C Zach, C la Fougere, A Rominger, A Drzezga, H Hampel, P Bartenstein, K Buerger; J Alzheimers Dis. 2011 Apr 15. [Epub ahead of print]
Effects of a Newly Developed Cognitive Intervention in Amnestic Mild Cognitive Impairment and mild Alzheimer's disease: A Pilot Study.
VC Buschert, U Friese, SJ Teipel, P Schneider, W Merensky, D Rujescu, HJ Möller, H Hampel, K Buerger; J Alzheimers Dis. 2011 Apr 11. [Epub ahead of print]
Evaluation of systemic targeting of RET oncogene-based MTC with tumor-selective peptide-tagged Ad vectors in clinical mouse models.
A Schmidt, C Eipel, K Fürst, N Sommer, J Pahnke, BM Pützer; Gene Ther. 2011 Apr;18(4):418-23. Epub 2011 Jan 13.
Determination of Spatial and Temporal Distribution of Microglia by 230nm-High-Resolution, High-Throughput Automated Analysis Reveals Different Amyloid Plaque Populations in an APP/PS1 Mouse Model of Alzheimer's Disease.
K Scheffler, J Stenzel, M Krohn, C Lange, J Hofrichter, T Schumacher, T Brüning, AS Plath, L Walker, J Pahnke; Curr Alzheimer Res. 2011 Jan 19. [Epub ahead of print]
Increased CSF-BACE1 Activity Associated with Decreased Hippocampus Volume in Alzheimer's Disease.
M Ewers, X Cheng, Z Zhong, HF Nural, C Walsh, T Meindl, SJ Teipel, K Buerger, P He, Y Shen, H Hampel; J Alzheimers Dis. 2011 Jan 1;25(2):373-381.
The PluriNetWork: an electronic representation of the network underlying pluripotency in mouse, and its applications.
A Som, C Harder, B Greber, M Siatkowski, Y Paudel, G Warsow, C Cap, H Schöler, G Fuellen; PLoS One. 2010 Dec 10;5(12):e15165.
Correspondence (letter to the editor):Definition of age.
T Fiss, W Hoffmann; Dtsch Arztebl Int. 2010 Dec;107(50):899-900. Epub 2010 Dec 17.
ExprEssence--revealing the essence of differential experimental data in the context of an interaction/regulation net-work.
G Warsow, B Greber, SS Falk, C Harder, M Siatkowski, S Schordan, A Som, N Endlich, H Schöler, D Repsilber, K Endlich, G Fuellen; BMC Syst Biol. 2010 Nov 30;4:164.
Automated detection of amyloid-beta-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI.
SJ Teipel, E Kaza, S Hadlich, A Bauer, T Brüning, AS Plath, M Krohn, K Scheffler, LC Walker, M Lotze, J Pahnke; J Alzheimers Dis. 2010 Oct 20.
Longitudinal changes in fiber tract integrity in healthy aging and mild cognitive impairment: a DTI follow-up study.
SJ Teipel, T Meindl, M Wagner, B Stieltjes, S Reuter, KH Hauenstein, M Filippi, U Ernemann, MF Reiser, H Hampel; J alzheimers Dis. 2010; 22(2): 507-22.
Zu viele alte Patienten nehmen ungeeignete Medikamente ein.
T Fiss; Med Mo Pharm 33(11):441-43, 2010
Diagnostic utility of novel MRI-based biomarkers for Alzheimer's disease: diffusion tensor imaging and deformation-based morphometry.
U Friese, T Meindl, SC Herpertz, MF Reiser, H Hampel, SJ Teipel; J Alzheimers Dis. 2010; 20(2):477-90.
Changing maternity leave policy: Short-term effects on fertility rates and demographic variables in Germany.
JR Thyrian, K Fendrich, A Lange, JP Haas, M Zygmunt, W Hoffmann; Soc Sci Med. 2010 Aug.
The relation of regional cerebral perfusion and atrophy in mild cognitive imperment (MCI) and early Alzheimer's dementia.
C Luckhaus, M Cohnen, MO Fluss, M Janner, B Grass-Kapanke, SJ Teipel, M Grothe, H Hampel, O Peters, J Kornhuber, W Maier, T Supprian, W Gaebel, U Modder, HJ Wittsack; Psychiatry Res. 2010 Jul 30; 183(1): 44-51.
The cholinergic system in mild cognitive impairment and Alzheimer's disease: An in vivo MRI and DTI study.
SJ Teipel, T Meindl, L Grinberg, M Grothe, JL Cantero, MF Reiser, HJ Möller, H Heinsen, H Hampel; Hum Brain mapp. 2010 Jul 29.
Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.
H Hampel, R Frank, K Broich, SJ Teipel, RG Katz, J Hardy, K Herholz, AL Bokde, F Jessen, YC Hoessler, WR Sanhai, H Zetterberg, J Woodcock, K Blennow; Nat Rev Drug Discov. 2010 July; 9(7): 560-74
Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease.
SJ Teipel, M Ewers, S Wolf, F Jessen, H Kölsch, S Arlt, C Luckhaus, P Schönknecht, K Schmidtke, I Heuser, L Frölich, G Ende, J Pantel, J Wiltfang, F Rakebrandt, O Peters, C Born, J Kornhuber, H Hampel; Psychiatry Res. 2010 Jun 30; 182(3):244-50. Epub 2010 May 20.
Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's disease.
W Koch, S Teipel, S Mueller, J Benninghoff, M Wagner, AL Bokde, H Hampel, U Coates, M Reider, T Meindl; Neurobiol Aging. 2010 Jun 10.
Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease.
C Plant, SJ Teipel, A Oswald, C Bohm, T Meindl, J Mourao-Miranda, et al.; Neuroimage 2010 Mar; 50(1): 162-74. Epub 2009 Dec 2.
White matter microstructure underlying default mode network connectivity in the human brain
SJ Teipel, AL Bokde, T Meindl, E Amaro Jr, J Soldner, MF Reiser, SC Herpertz, HJ Moeller, H Hampel; Neuroimage 2010 Feb 1; 49(3): 2021-32. Epub 2009 Oct 28.
Age-related networks of regional covariance in MRI gray matter: Reproducible multivariate patterns in healthy aging
KL Bergfield, KD Hanson, K Chen, SJ Teipel, H Hampel, SI Rapoport, JR Moeller, GE Alexander; Neuroimage 2010 Jan 15; 49(2): 1750-9. Epub 2009 Sep 28.